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Kynurenic acid

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Identification
Molecular formula
C10H7NO3
CAS number
118-79-6
IUPAC name
8-amino-8-oxo-oct-2-en-4,6-diynoic acid
State
State

At room temperature, kynurenic acid is found in a solid state. It is typically stable and is commonly used in its salt form due to its insolubility in water.

Melting point (Celsius)
205.00
Melting point (Kelvin)
478.15
Boiling point (Celsius)
338.00
Boiling point (Kelvin)
611.15
General information
Molecular weight
189.17g/mol
Molar mass
189.1660g/mol
Density
2.1864g/cm3
Appearence

Kynurenic acid typically appears as an off-white to yellowish crystalline solid. It is often encountered in its crystalline form which can have a slightly acetone-like odor.

Comment on solubility

Solubility of 8-amino-8-oxo-oct-2-en-4,6-diynoic acid

The solubility of 8-amino-8-oxo-oct-2-en-4,6-diynoic acid can be characterized by several key aspects:

  • Polarity: This compound contains functional groups that contribute to its overall polarity, influencing its solubility in polar solvents such as water.
  • Hydrogen Bonding: The presence of amino (-NH2) and carboxylic acid (-COOH) groups enables the formation of hydrogen bonds, further enhancing solubility in aqueous solutions.
  • Organic Solvent Compatibility: Depending on the chain length and the structure of the compound, it may exhibit varying solubility in organic solvents such as ethanol and dimethyl sulfoxide (DMSO).
  • Temperature Dependence: Solubility can also be influenced by temperature; typically, increasing the temperature of the solvent may enhance the solubility of organic compounds.

In summary, the solubility of 8-amino-8-oxo-oct-2-en-4,6-diynoic acid is expected to be moderate in water due to the presence of polar functional groups, while its behavior in organic solvents may vary considerably based on chain interactions and solvent properties. Understanding these characteristics is crucial for practical applications in synthesis and formulation.

Interesting facts

Interesting Facts about 8-amino-8-oxo-oct-2-en-4,6-diynoic acid

8-amino-8-oxo-oct-2-en-4,6-diynoic acid, often abbreviated as AOAA, is a fascinating compound that lies at the intersection of organic chemistry and biochemistry. This compound is known for its unique structure and potential applications in various fields, particularly in medicinal chemistry.

Structural Highlights

  • Amino and Ketone Functionalities: The presence of both amino and keto groups in the structure makes it an intriguing subject for reaction mechanisms.
  • Diynes: The compound features a di-yne moiety, which can contribute to the compound's reactivity and potentially to its biological activity.

Due to its structural properties, 8-amino-8-oxo-oct-2-en-4,6-diynoic acid serves as an essential building block in the synthesis of various pharmaceuticals.
For instance, it is involved in the production of amino acid derivatives and other complex organic molecules.

Potential Applications

  • Drug Discovery: There is ongoing research focused on its potential role in developing new therapeutics.
  • Biochemical Studies: This compound is used in studies aimed at understanding enzyme mechanisms and biological pathways.

As a testament to its significance, scientists often quote the importance of such compounds: "Understanding the nuances of complex organic molecules is crucial for advancing modern medicine." Overall, 8-amino-8-oxo-oct-2-en-4,6-diynoic acid exemplifies the rich interplay between chemistry and biology, showcasing how intricate the world of chemical compounds can be.

Synonyms
8-Amino-8-oxo-2-octene-4,6-diynoic acid
544-04-7
8-amino-8-oxooct-2-en-4,6-diynoic acid
DTXSID501280539