Skip to main content

Notch inhibitors (compound E)

ADVERTISEMENT
Identification
Molecular formula
C25H21N3O4
CAS number
911417-87-3
IUPAC name
8-benzyl-2-hydroxy-6-(4-hydroxyphenyl)-2-[(4-hydroxyphenyl)methyl]imidazo[1,2-a]pyrazin-3-one
State
State
The compound is typically a solid at room temperature.
Melting point (Celsius)
310.00
Melting point (Kelvin)
583.15
Boiling point (Celsius)
520.00
Boiling point (Kelvin)
793.15
General information
Molecular weight
407.46g/mol
Molar mass
407.4170g/mol
Density
1.3000g/cm3
Appearence

The compound generally appears as a white to off-white solid.

Comment on solubility

Solubility of 8-benzyl-2-hydroxy-6-(4-hydroxyphenyl)-2-[(4-hydroxyphenyl)methyl]imidazo[1,2-a]pyrazin-3-one

The solubility of the compound 8-benzyl-2-hydroxy-6-(4-hydroxyphenyl)-2-[(4-hydroxyphenyl)methyl]imidazo[1,2-a]pyrazin-3-one (C25H21N3O4) is influenced by various factors reflecting its complex structure. This compound contains multiple hydroxyl groups and a pyrazinone moiety that can interact with polar solvents, potentially enhancing its solubility in certain conditions.

Key Factors Affecting Solubility:

  • Polarity: The presence of hydroxyl (-OH) groups suggests increased polarity, which typically allows soluble interactions with polar solvents such as water.
  • Hydrogen Bonding: Hydroxyl groups can form hydrogen bonds, contributing to solubility in alcohols and other hydrogen-bonding solvents.
  • Structural Complexity: The bulky benzyl and phenyl substitutions may hinder solubility in highly polar solvents, suggesting a preference for less polar environments.
  • pH Dependence: The ionization state can shift with pH changes, potentially affecting solubility in aqueous solutions.

Overall, while the compound may exhibit moderate solubility in some polar solvents, it is essential to consider its structural characteristics and environmental conditions when assessing solubility. As with many complex organic compounds, predicting solubility metrics can be challenging but rewarding in understanding its behavior in various media.

Interesting facts

Interesting Facts about 8-benzyl-2-hydroxy-6-(4-hydroxyphenyl)-2-[(4-hydroxyphenyl)methyl]imidazo[1,2-a]pyrazin-3-one

This compound, known for its complex structure, belongs to the imidazopyrazine family which is often investigated for its diverse biological activities. Below are some interesting insights:

  • Pharmacological Potential: The presence of the imidazo and pyrazine rings in this compound suggests potential as a pharmaceutical agent, especially in fields like anticancer research, where molecular complexity often correlates with multi-target activity.
  • Hydroxyl Functional Groups: The multiple hydroxyl (-OH) groups not only enhance solubility in biological systems but also play crucial roles in hydrogen bonding, potentially influencing the compound's reactivity and stabilization of molecular interactions.
  • Benzyl Variability: With benzyl units integrated into its structure, this compound may exhibit interesting behavior in varying solvent environments, leading to unique outcomes in molecular recognition processes.
  • Structurally Unique: This compound features notable features: an imidazo[1,2-a]pyrazine core that lies at the intersection of various fields such as medicinal chemistry and material science.

As a chemist or student, it is fascinating to explore such compounds that embody both intricate chemistry and potential applications. The nature of molecular interactions within this compound could yield significant insights for developing novel therapies or investigative tools in chemical biology.

In the words of famous chemist Linus Pauling: "The best way to have a good idea is to have lots of ideas." Exploring compounds like this often leads to the serendipitous discovery of groundbreaking solutions!

Synonyms
SCHEMBL4323507
PD042741