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Brimonidine Tartrate

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Identification
Molecular formula
C15H10BrN5O2
CAS number
70144-77-5
IUPAC name
8-bromo-1,3-dimethyl-7H-purine-2,6-dione;N'-[(4-methoxyphenyl)methyl]-N,N-dimethyl-N'-(2-pyridyl)ethane-1,2-diamine
State
State

At room temperature, Brimonidine Tartrate is typically found in a solid state. It is stable under normal temperatures and pressures.

Melting point (Celsius)
250.00
Melting point (Kelvin)
523.15
Boiling point (Celsius)
393.10
Boiling point (Kelvin)
666.25
General information
Molecular weight
442.24g/mol
Molar mass
442.2430g/mol
Density
1.6930g/cm3
Appearence

Brimonidine Tartrate appears as an off-white to pale yellow crystalline powder. It's generally observed to be hygroscopic, meaning it can absorb moisture from the environment.

Comment on solubility

Solubility of 8-bromo-1,3-dimethyl-7H-purine-2,6-dione; N'-[(4-methoxyphenyl)methyl]-N,N-dimethyl-N'-(2-pyridyl)ethane-1,2-diamine

The solubility of this compound is influenced by its complex structure and functional groups. Several factors contribute to its solubility behavior:

  • Polarity: With multiple polar functional groups (including amines and methoxy groups), the compound exhibits increased interactions with polar solvents, which often enhances solubility in water and alcohols.
  • Hydrogen Bonding: The presence of nitrogen and oxygen atoms allows for significant hydrogen bonding with solvent molecules, facilitating solvation.
  • Size and Shape: The bulky and branched structure may hinder solubility in non-polar solvents, suggesting limited solubility in hydrocarbons.
  • pH Dependence: Variations in pH can affect the ionization of the amine groups, further influencing solubility in aqueous environments.

In summary, the solubility of this compound can be described as variable:

  1. More soluble in polar solvents like methanol and ethanol
  2. Possibly less soluble in non-polar solvents such as hexane

As a general observation, the intricate balance of polarity, size, and the ability to form hydrogen bonds plays a crucial role in predicting the solubility of this complex organic compound.

Interesting facts

Interesting Facts about the Compound

8-bromo-1,3-dimethyl-7H-purine-2,6-dione; N'[(4-methoxyphenyl)methyl]-N,N-dimethyl-N'-(2-pyridyl)ethane-1,2-diamine is a fascinating compound with significant implications in the field of medicinal chemistry. Here are some noteworthy points:

  • Pharmacological Potential: This compound is part of a class of substances that show promise as potential therapeutic agents. Compounds with purine structures are often explored for their roles in antivirus and anticancer research.
  • Complex Design: The synthesis of this compound involves sophisticated organic chemistry techniques, including the functionalization of purine derivatives, which are known for their biological importance as components of nucleotides.
  • Versatile Applications: The presence of both purine and aromatic amine groups suggests that this compound could be evaluated for its activity as an enzyme inhibitor, particularly in processes involving nucleic acids.

This compound exemplifies the intricate relationship between structure and function in the realm of drug discovery. As researchers unravel its properties, it may pave the way for innovative treatments in various medical fields. The exploration of such compounds not only enhances our understanding of biochemical systems but also emphasizes the importance of interdisciplinary collaboration in achieving breakthroughs in medicine.

Synonyms
PYRABROM
Pyrabrom [USAN]
606-05-3
SMP 68-40
UNII-360MH2GO0I
Pyrabrom (USAN)
360MH2GO0I
NSC14279
NSC 14279
NSC-14279
DTXSID40209398
SMP-68-40
8-Bromotheophylline compound with 2-((2-(dimethylamino)ethyl)(p-methoxybenzyl)amino)pyridine (1:1)
DTXCID60131889
Donasil
Glybrom
Mensalin
Parbrom
Sanbromal
Bromth
Pyrilamine 8-bromotheophyllinate
Pyranisamine 8-bromotheophyllinate
8-Bromotheophylline compound with 2-[[2-dimethylamino)ethyl](p-methoxybenzyl)amino]pyridine (1:1)
Pyrabrom(USAN)
SCHEMBL637132
CHEMBL1965464
NCI60_000935
D05656
Q27256498
{2-[[2-(Dimethylamino)ethyl](p-methoxybenzyl)amino]pyridine} 8-bromotheophyllinate
2-[[2-(Dimethylamino)ethyl](p-methoxybenzyl)amino]pyridine 8-bromotheophyllinate
8-Bromo-1,3-dimethyl-3,9-dihydro-1H-purine-2,6-dione compound with N~1~-(4-methoxybenzyl)-N~2~,N~2~-dimethyl-N~1~-(2-pyridinyl)-1,2-ethanediamine (1:1)
8-bromo-1,3-dimethyl-9H-purine-2,6-dione; N'-[(4-methoxyphenyl)methyl]-N,N-dimethyl-N'-(2-pyridyl)ethane-1,2-diamine
8-Bromotheophylline compound with {2-[[2-dimethylamino)ethyl](p-methoxybenzyl)amino]pyridine} (1:1)