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8-Bromotheophylline

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Identification
Molecular formula
C7H7BrN4O2
CAS number
10381-26-3
IUPAC name
8-bromo-3,7-dihydropurine-2,6-dione
State
State

At room temperature, 8-Bromotheophylline exists as a solid. It remains stable and retains its form under standard laboratory conditions.

Melting point (Celsius)
285.00
Melting point (Kelvin)
558.15
Boiling point (Celsius)
631.30
Boiling point (Kelvin)
904.45
General information
Molecular weight
269.06g/mol
Molar mass
269.0800g/mol
Density
2.1265g/cm3
Appearence

8-Bromotheophylline is typically found as a white crystalline powder. The crystals are highly pure and can exhibit slight variations in color depending on the preparation method used.

Comment on solubility

Solubility of 8-bromo-3,7-dihydropurine-2,6-dione

8-bromo-3,7-dihydropurine-2,6-dione (C7H7BrN4O2) is a fascinating chemical compound with unique solubility characteristics. Understanding its solubility can provide insights into its applications and behavior in different environments. Here are some key points regarding its solubility:

  • Solvent Compatibility: This compound is known to be soluble in polar organic solvents such as dimethyl sulfoxide (DMSO) and ethanol. However, its solubility in water is relatively low due to the presence of the bromine atom, which can influence the overall polarity of the molecule.
  • Temperature Influence: Generally, the solubility of organic compounds, including 8-bromo-3,7-dihydropurine-2,6-dione, can be affected by temperature. Increased temperatures often enhance solubility, making the compound more favorable for applications requiring higher concentrations.
  • pH Sensitivity: The compound may exhibit different solubility profiles at varying pH levels. For instance, under acidic conditions, it might be more soluble due to protonation phenomena which can help stabilize the compound in solution.
  • Applications in Pharmaceuticals: Understanding the solubility of this compound is critical in pharmaceuticals, particularly for formulation development where solubility directly impacts bioavailability.

In essence, the solubility of 8-bromo-3,7-dihydropurine-2,6-dione is an essential property that influences its potential applications in various fields, particularly medicinal chemistry. Knowledge about how it interacts with different solvents can drive innovation in drug formulation and therapeutic use.

Interesting facts

Interesting Facts About 8-Bromo-3,7-Dihydropurine-2,6-Dione

8-Bromo-3,7-dihydropurine-2,6-dione is a fascinating compound that has drawn attention in various fields of research, particularly in medicinal chemistry and biochemistry. Here are some compelling points to consider:

  • Structural Insights: This compound belongs to the purine family, which is essential in the construction of nucleotides—components of DNA and RNA. The inclusion of bromine at the 8 position suggests unique reactivity, influencing its biological behavior.
  • Biological Relevance: Due to its structural similarity to adenine and guanine, it has been explored for its potential as an antagonist or modulator of purinergic receptors, which are pivotal in numerous physiological processes.
  • Research Applications: The compound is often utilized in the synthesis of compounds intended for pharmacological studies, especially in exploring therapeutic avenues for conditions such as cancer or viral infections.
  • Reactivity and Synthesis: The presence of the bromine atom can facilitate reactions such as nucleophilic substitution, making it a valuable intermediate in organic synthesis.
  • Potential Therapeutic Uses: Compounds of this nature have shown promise in the development of antivirals and nucleoside analogs, potentially paving the way for innovative treatments in the pharmaceutical industry.

As a chemistry student, exploring the intricacies of 8-bromo-3,7-dihydropurine-2,6-dione can invoke a deeper understanding of how modifications at specific sites can dramatically alter the properties and functionalities of biologically relevant molecules. Its ability to simulate natural substrates is a testament to the delicate balance in molecular design.

In summary, 8-bromo-3,7-dihydropurine-2,6-dione showcases the impressive capabilities of synthetic modifications in the realm of biochemistry, making it an intriguing subject for further investigation.

Synonyms
8-BROMOXANTHINE
10357-68-3
8-Bromo-1H-purine-2,6(3H,7H)-dione
Xanthine, 8-bromo-
8-bromo-3,7-dihydropurine-2,6-dione
8-Bromopurine-2,6-diol
1H-Purine-2,6-dione, 8-bromo-3,7-dihydro-
8-bromo-3,9-dihydro-1H-purine-2,6-dione
NSC-24131
1JQ13K1223
C5H3BrN4O2
UNII-1JQ13K1223
1H-Purine-2,6-dione, 8-bromo-3,9-dihydro-
8-Bromo-3,7-dihydro-1H-purine-2,6-dione; 8-Bromo-xanthine; 8-Bromopurine-2,6-diol; NSC 24131
NSC 24131
8-Bromoxanthine, 3
SCHEMBL932949
SCHEMBL4514252
SCHEMBL14793521
BDBM85772
DTXSID80145903
ZFQWSCZYQLPFFZ-UHFFFAOYSA-N
NSC24131
MFCD22123145
AKOS005198770
FS-5607
1H-Purine-2, 8-bromo-3,7-dihydro-
DB-081557
CS-0102954
NS00023248
C71150
8-bromo-2,3,6,7-tetrahydro-1H-purine-2,6-dione
Q27252506