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8-chlorotheophylline

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Identification
Molecular formula
C7H7ClN4O2
CAS number
85-18-7
IUPAC name
8-chloro-3,7-dihydropurine-2,6-dione
State
State

At room temperature, 8-chlorotheophylline is a solid. It maintains its crystalline structure unless subjected to temperatures near its melting point.

Melting point (Celsius)
277.00
Melting point (Kelvin)
550.15
Boiling point (Celsius)
607.00
Boiling point (Kelvin)
880.15
General information
Molecular weight
226.58g/mol
Molar mass
226.5810g/mol
Density
1.5410g/cm3
Appearence

8-Chlorotheophylline is a yellow crystalline compound. It is known for its distinct crystalline structure and often details on its crystalline formation are studied closely under laboratory conditions.

Comment on solubility

Solubility of 8-Chloro-3,7-dihydropurine-2,6-dione

When examining the solubility of 8-chloro-3,7-dihydropurine-2,6-dione, several key points arise that highlight its behavior in different solvents:

  • Solvent Compatibility: This compound is known to exhibit variable solubility depending on the solvent used. For instance, it readily dissolves in polar solvents such as water and methanol due to its polar functional groups.
  • Inorganic Solvents: Its solubility in non-polar solvents like benzene or hexane is quite limited. The presence of chlorine and nitrogen functionalities impacts the overall hydrophilicity of the molecule.
  • Temperature Effects: Increasing the temperature often enhances the solubility of this compound, a common phenomenon in many organic compounds, which could be attributed to increased molecular motion.
  • pH Sensitivity: The solubility may also vary with pH; under certain conditions, the presence of acidic or basic environments can influence the ionization state of the compound, thereby affecting its solubility.

In summary, while 8-chloro-3,7-dihydropurine-2,6-dione is primarily soluble in polar solvents, its solubility characteristics are impacted by various factors including solvent choice, temperature, and pH levels. This makes it essential for researchers to consider these factors when preparing solutions for experimental purposes.

Interesting facts

Interesting Facts about 8-Chloro-3,7-Dihydropurine-2,6-Dione

8-Chloro-3,7-dihydropurine-2,6-dione is an intriguing compound that belongs to the class of purine derivatives, which are vital for many biological processes. Below are some fascinating aspects of this molecular structure and its significance:

Biological Importance

  • Antiviral Properties: This compound has been studied for its potential antiviral activities, particularly in the context of treating infections caused by certain viruses.
  • Metabolic Influence: Being a purine derivative, it can influence purine metabolism, which is crucial for DNA and RNA synthesis, as well as energy transfer within cells.
  • Pharmaceutical Applications: Due to its structural similarity to natural nucleobases, researchers have explored this compound for its possible applications in drug design and development.

Chemical Structure and Properties

  • Chlorination: The presence of a chlorine atom contributes unique reactivity, often enhancing the compound's biological activity.
  • Hydropurine Base: As a hydropurine, it contains a bicyclic structure that is characteristic of purines, aiding in various biochemical reactions.

Research and Discoveries

This compound serves as an essential building block in molecular research and serves as a model for synthetic chemistry experimentation, providing insights into modifying nucleobases for specific therapeutic targets.

In conclusion, 8-chloro-3,7-dihydropurine-2,6-dione is more than just a chemical formula; it is a bridge between organic chemistry and the world of biological functions, opening doors to innovative treatments in health and medicine.

Synonyms
8-CHLOROXANTHINE
13548-68-0
Xanthine, 8-chloro-
8-chloro-3,9-dihydro-1H-purine-2,6-dione
8-chloro-3,7-dihydropurine-2,6-dione
8-Chloro-1H-purine-2,6(3H,7H)-dione
8-Chloro-9H-purine-2,6-diol
8-Chloro-3,7-dihydro-1H-purine-2,6-dione
NSC45762
1H-Purine-2,6-dione, 8-chloro-3,7-dihydro-
8-chloro-2,3,6,7-tetrahydro-1H-purine-2,6-dione
NSC-45762
1H-purine-2,6-dione, 8-chloro-3,9-dihydro-
C5H3ClN4O2
8-Chloroxanthin
8-chloro-Xanthine
8-ChloroT
NSC 45762
AI3-52416
2.6-Dioxy-8-chlorpurin
8-chlor-9H-purin-2,6-diol
R4A285B7AC
SCHEMBL2837685
SCHEMBL9465801
SCHEMBL9465804
BDBM82523
DTXSID00929020
CHEBI:178141
ALBB-023323
MFCD00213672
AKOS003368040
AKOS006273538
AKOS015904972
FC09024
8-chloro-1,3-dihydropurine-2,6-dione
1H-Purine-2, 8-chloro-3,7-dihydro-
6-hydroxy-7,9-dihydro-8H-purin-8-one
CAS_13548-68-0
DB-042291
ST45024133
8-chloro-3, 7-dihydro-1H-Purine-2,6-dione
8-Chloro-3,7-dihydro-1H-purine-2,6-dione #
1H-Purine-2,6-dione, 8-chloro-3, 7-dihydro-
1H-Purine-2,6-dione,8-chloro-3,7-dihydro-(9ci)
8-Chloroxanthine;8-chloro-3,9-dihydro-1H-purine-2,6-dione