Interesting facts
              Interesting Facts about 8-Chloro-6-(2-fluorophenyl)-1-methyl-4H-imidazo[1,5-a][1,4]benzodiazepine
8-Chloro-6-(2-fluorophenyl)-1-methyl-4H-imidazo[1,5-a][1,4]benzodiazepine, often abbreviated as a complex name, is a fascinating compound in the realm of medicinal chemistry and pharmacology. Below are some engaging insights into this compound:
- Pharmacological Relevance: This compound belongs to the benzodiazepine family, which is renowned for its sedative, anxiolytic, and muscle relaxant properties. Its structure suggests potential for significant therapeutic effects.
 - Chlorine's Role: The presence of chlorine in the structure often enhances biological activity. It can alter lipophilicity and influence how the drug interacts with biological membranes and targets in the body.
 - Fluorine Substitution: The incorporation of fluorine into organic compounds typically modifies reactivity and pharmacokinetics. This specific substitution can enhance the binding affinity of the compound to certain receptors, potentially increasing its efficacy.
 - Imidazole Integration: The imidazo ring system in this compound is integral to its activity. Imidazole derivatives are of great interest due to their role in various biological processes, often acting as signaling molecules in the body.
 - Research Potential: Scientists are interested in compounds like this one for their ability to modulate neurotransmitter systems, particularly in the context of disorders such as anxiety and depression. The ongoing research could lead to the development of novel therapeutic agents.
 
To summarize, the unique structural features and potential applications of 8-chloro-6-(2-fluorophenyl)-1-methyl-4H-imidazo[1,5-a][1,4]benzodiazepine make it a compound of significant interest. Its ongoing study could unveil new pathways in drug development, inspiring a new generation of treatments.
Synonyms
          midazolam
          Dormicum
          59467-70-8
          Buccolam
          Midazolamum
          Versed
          8-Chloro-6-(2-fluorophenyl)-1-methyl-4H-imidazo[1,5-a][1,4]benzodiazepine
          mezolam
          Midazolamum [INN-Latin]
          Midazolam Base
          Nayzilam
          Midazolam civ
          USL261
          Ro 21-3981
          DEA No. 2884
          UNII-R60L0SM5BC
          EINECS 261-774-5
          R60L0SM5BC
          BRN 0625572
          CHEBI:6931
          USL-261
          CHEMBL655
          8-Chlor-6-(2-fluorphenyl)-1-methyl-4H-imidazo(1,5-a)(1,4)benzodiazepin
          8-Chloro-6-(o-fluorophenyl)-1-methyl-4H-imidazo(1,5-a)(1,4)benzodiazepine
          DTXSID5023320
          HSDB 6751
          Midazolam [USP:INN:BAN:JAN]
          USL261 (nasal spray formulation)
          4H-Imidazo(1,5-a)(1,4)benzodiazepine, 8-chloro-6-(2-fluorophenyl)-1-methyl-
          Midazolamum (INN-Latin)
          MIDAZOLAM (MART.)
          MIDAZOLAM [MART.]
          4H-Imidazo[1,5-a][1,4]benzodiazepine, 8-chloro-6-(2-fluorophenyl)-1-methyl-
          8-Chloro-6-(O-fluorophenyl)-1-methyl-4H-imidazo[1,5-a][1,4]-benzodiazepine
          MIDAZOLAM CIV (USP-RS)
          MIDAZOLAM CIV [USP-RS]
          MIDAZOLAM (EP MONOGRAPH)
          MIDAZOLAM [EP MONOGRAPH]
          MIDAZOLAM (USP MONOGRAPH)
          Midazolam (USP:INN:BAN:JAN)
          MIDAZOLAM [USP MONOGRAPH]
          Midazolam (1.0 mg/mL in methanol)
          8-chloro-6-(2-fluorophenyl)-1-methyl-4h-imidazo(1,5-a)(1,4)benzodiazepine
          4H-IMIDAZO(1,5-A)(1,4)BENZODIAZEPINE, 8-CHLORO-6-(2-FLUOROPHENYL)-1-METHYL
          Dormicum (TN)
          12-chloro-9-(2-fluorophenyl)-3-methyl-2,4,8-triazatricyclo[8.4.0.0^{2,6}]tetradeca-1(10),3,5,8,11,13-hexaene
          NCGC00168254-01
          Medazolam
          Buccolam (TN)
          Nayzilam (TN)
          08J
          Midazolamum (Latin)
          Versed (Salt/Mix)
          Dormonid (Salt/Mix)
          Hypnovel (Salt/Mix)
          Flormidal (Salt/Mix)
          MIDAZOLAM [INN]
          MIDAZOLAM [JAN]
          MIDAZOLAM [MI]
          MIDAZOLAM [VANDF]
          MIDAZOLAM [WHO-DD]
          Midazolam (JAN/USP/INN)
          Midazolam Injection, 10 mg
          SCHEMBL35061
          BIDD:GT0647
          Midazolam hydrochloride, solid
          Midazolam, 1mg/ml in Methanol
          DTXCID503320
          GTPL3342
          MIDAZOLAM [ORANGE BOOK]
          BDBM21363
          N05CD08
          Midazolam 0.1 mg/ml in Methanol
          Midazolam 1.0 mg/ml in Methanol
          BCP21296
          HY-B0676
          59467-70-8 (free)
          AKOS015842580
          DB00683
          FM25999
          4H-Imidazo[1,5-a][1,4]benzodiazepine, 8-chloro-6-(2-fluoro-phenyl)-1-methyl-, (Z)-2-butenedioate
          MIDAZOLAM IN 0.8% SODIUM CHLORIDE
          MIDAZOLAM IN 0.9% SODIUM CHLORIDE
          DB-015270
          NS00000476
          C07524
          D00550
          A832332
          Q423071
          Midazolam hydrochloride, United States Pharmacopeia (USP) Reference Standard
          12-chloro-9-(2-fluorophenyl)-3-methyl-2,4,8-triazatricyclo[8.4.0.0^{2,6}]tetradeca-1(14),3,5,8,10,12-hexaene
          261-774-5
          8-Chloro-6-(2-fluorophenyl)-1-methyl-4H-imidazo[1,5-a][1,4]benzodiazepine;Dazolam;Dormicum
              
Solubility of 8-chloro-6-(2-fluorophenyl)-1-methyl-4H-imidazo[1,5-a][1,4]benzodiazepine
The solubility of 8-chloro-6-(2-fluorophenyl)-1-methyl-4H-imidazo[1,5-a][1,4]benzodiazepine (C18H13ClFN3) can be influenced by a variety of factors, including its chemical structure and the nature of solvents used. Here are some key considerations regarding its solubility:
In many cases, compounds like this may exhibit limited solubility in water, which is a common characteristic of benzodiazepine derivatives due to their complex aromatic structures. For practical applications, understanding the solubility profile is essential, as it determines the compound's bioavailability, efficacy, and formulation characteristics in pharmaceutical contexts.
In summary, the solubility of C18H13ClFN3 can be summarized with the following points:
Emphasizing these aspects aids in understanding the behavior of this compound in various environments.