Interesting facts
Interesting Facts about 8-Chloro-6-(4-methylpiperazin-1-yl)-11H-benzo[b][1,4]benzodiazepine
8-Chloro-6-(4-methylpiperazin-1-yl)-11H-benzo[b][1,4]benzodiazepine is an intriguing compound that belongs to the class of benzodiazepines, known for their significant pharmacological properties. Here are some captivating insights about this compound:
- Pharmacological Importance: This compound exhibits remarkable activity as a central nervous system (CNS) depressant. It is believed to have anxiolytic, sedative, and anticonvulsant effects, making it a potential candidate for various therapeutic applications.
- Structural Features: The incorporation of both chlorine and piperazine groups into its structure contributes to its unique binding affinity to GABAA receptors. The presence of the piperazinyl moiety enhances the compound's effectiveness compared to other benzodiazepines.
- Research Potential: Researchers are exploring this compound for its possible role in treating anxiety disorders and other related conditions. Its structural resemblance to existing benzodiazepines leads scientists to predict a variety of pharmacological effects.
- Mechanism of Action: Like many benzodiazepines, it is believed to enhance the effects of the neurotransmitter gamma-aminobutyric acid (GABA), leading to increased inhibitory transmission in the CNS. This mechanism is crucial for its therapeutic effects.
- Chemistry and Synthesis: The synthesis of this compound involves intricate organic reactions, highlighting the importance of synthetic organic chemistry in drug development. Understanding its synthesis can lead to innovations in creating novel compounds with enhanced properties.
As the study of benzodiazepines continues to expand, 8-chloro-6-(4-methylpiperazin-1-yl)-11H-benzo[b][1,4]benzodiazepine stands out as a compound worth investigating due to its potential implications in therapeutic applications and the remarkable chemistry behind its formation.
Synonyms
ISOCLOZAPINE
2-Chloro-11-(4-methyl-1-piperazinyl)-5H-dibenzo(b,e)(1,4)diazepine
1977-08-8
4Q6V732VRT
CHEMBL415300
8-chloro-6-(4-methylpiperazin-1-yl)-11H-benzo[b][1,4]benzodiazepine
2-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine
5H-DIBENZO(b,e)(1,4)DIAZEPINE, 2-CHLORO-11-(4-METHYL-1-PIPERAZINYL)-
BRN 0763655
UNII-4Q6V732VRT
SCHEMBL140207
DTXSID40173464
BAA97708
2-Chloro-11-(4-methyl-1-piperazinyl)-5H-benzo(b,e)(1,4)diazepine
BDBM50010594
NCGC00386501-01
DB-217114
E98703
2-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine(isoclozapine)
8-CHLORANYL-6-(4-METHYLPIPERAZIN-1-YL)-11H-BENZO(B)(1,4)BENZODIAZEPINE
Solubility of 8-chloro-6-(4-methylpiperazin-1-yl)-11H-benzo[1,4]benzodiazepine
The solubility of 8-chloro-6-(4-methylpiperazin-1-yl)-11H-benzo[1,4]benzodiazepine is a critical aspect for its practical applications, particularly in pharmaceutical formulations. Generally speaking, the solubility of organic compounds, especially those containing complex structures such as this benzodiazepine derivative, can be influenced by several factors:
For this specific compound, it's important to note that its solubility profile may vary greatly depending on the solvent used. As a guideline:
Overall, understanding the solubility of 8-chloro-6-(4-methylpiperazin-1-yl)-11H-benzo[1,4]benzodiazepine is crucial for its utilization in biological systems and its effective incorporation into drug formulations. Each characteristic must be explored through empirical methods to draw accurate conclusions regarding its solubility behavior.