Interesting facts
Interesting Facts about 8-Chloro-6-(4-Methylpiperazin-1-yl)benzo[b][1,4]benzothiazepine
The compound 8-chloro-6-(4-methylpiperazin-1-yl)benzo[b][1,4]benzothiazepine belongs to a unique class of chemical compounds known for their diverse applications in medicinal chemistry. Here are some fascinating insights:
- Structural Complexity: This compound features a complex polycyclic structure that includes a benzothiazepine framework, which contributes to its interesting chemical properties and biological activities.
- Pharmacological Potential: Compounds of this nature are often researched for their potential therapeutic effects. They may exhibit properties such as antipsychotic or antidepressant activities, making them of interest in mental health research.
- Chlorine Substitution: The presence of chlorine in its structure can influence the compound's reactivity and its interaction with biological targets, leading to enhanced efficacy in comparison with its non-chlorinated analogs.
- Piperazine Moiety: The 4-methylpiperazine group attached to the benzothiazepine plays a crucial role in modulating biological activity. This moiety often acts as a bridge, connecting the pharmacophore to specific receptors.
- Research Applications: Scientists are continually exploring compounds like this for drug development, especially in the areas of neuropharmacology and psychopharmacology, aiming for breakthroughs in treatments.
As we delve deeper into the study of such compounds, it's essential to consider not only their structures but also their biological implications. As one researcher aptly stated, "Understanding the nuances of molecular interactions can unlock new avenues in therapy." This underscores the importance of compounds like 8-chloro-6-(4-methylpiperazin-1-yl)benzo[b][1,4]benzothiazepine in advancing our knowledge of medicinal chemistry.
Synonyms
Clothiapine
Clotiapine
Entumin
Entumine
Etumine
Clothiapine [USAN]
Dibenzo[b,f][1,4]thiazepine, 2-chloro-11-(4-methyl-1-piperazinyl)-
Clotiapinum [INN-Latin]
Clotiapina [INN-Spanish]
Clotiapine [INN]
HF 2159
S-805C
DIBENZO(b,f)(1,4)THIAZEPINE, 2-CHLORO-11-(4-METHYL-1-PIPERAZINYL)-
UNII-Z05HCY0X1T
EINECS 218-162-8
Z05HCY0X1T
Entumin (TN)
HF-2159
LW 2159
BRN 0568276
Clothiapine (USAN)
DTXSID5022851
2-Chloro-11-(4-methyl-1-piperazinyl)dibenzo(b,f)(1,4)thiazepine
Clotiapine (JAN/INN)
CLOTHIAPINE [MI]
CLOTIAPINE [JAN]
2-Chloro-11-(4-methylpiperazino)dibenzo(b,f)(1,4)thiazepine
CLOTIAPINE [MART.]
CLOTIAPINE [WHO-DD]
DTXCID702851
W 130
2-chloro-11-(4-methyl-1-piperazinyl)dibenzo[b,f][1,4]thiazepine
Clotiapinum (INN-Latin)
Clotiapina (INN-Spanish)
CLOTIAPINE (MART.)
13-chloro-10-(4-methylpiperazin-1-yl)-2-thia-9-azatricyclo(9.4.0.03,?)pentadeca-1(11),3,5,7,9,12,14-heptaene
13-chloro-10-(4-methylpiperazin-1-yl)-2-thia-9-azatricyclo[9.4.0.03,?]pentadeca-1(11),3,5,7,9,12,14-heptaene
N05AH06
kaazgxdpunnefn-uhfffaoysa-n
2058-52-8
Clotiapina
8-chloro-6-(4-methylpiperazin-1-yl)benzo[b][1,4]benzothiazepine
CHEMBL304902
NCGC00160387-01
2-chloro-11-(4-methylpiperazin-1-yl)dibenzo[b,f][1,4]thiazepine
Clotiapinum
CAS-2058-52-8
Biomol-NT_000008
SCHEMBL122941
BPBio1_001137
CHEBI:31424
CHEBI:108591
HMS2089L15
BCP06511
Tox21_111779
BDBM50040237
PDSP1_000469
PDSP2_000467
AKOS005065858
Tox21_111779_1
DB13256
MRF-0000024
NCGC00160387-02
NCGC00160387-03
NCGC00160387-04
FC178187
DB-045296
HY-117083
CS-0063673
NS00004358
D01597
H20646
SBI-0654076.0001
AB01275460-01
EN300-26485788
SR-05000001467
Q3661095
SR-05000001467-1
BRD-K10990317-001-01-1
BRD-K10990317-001-02-9
BRD-K10990317-001-04-5
8-chloro-6-(4-methyl-1-piperazinyl)benzo[b][1,4]benzothiazepine
2-Chloro-11-(4-methyl-piperazin-1-yl)-dibenzo[b,f][1,4]thiazepine
2-Chloro-11-(4-methyl-piperazin-1-yl)-dibenzo[b,f][1,4]thiazepine(clothiapine)
13-chloro-10-(4-methylpiperazin-1-yl)-2-thia-9-azatricyclo[9.4.0.0,3,8]pentadeca-1(11),3(8),4,6,9,12,14-heptaene
Solubility of 8-chloro-6-(4-methylpiperazin-1-yl)benzo[b][1,4]benzothiazepine
The solubility of 8-chloro-6-(4-methylpiperazin-1-yl)benzo[b][1,4]benzothiazepine can be influenced by various factors, including its molecular structure and interaction with solvents. Here are some key points regarding its solubility:
In summary, while 8-chloro-6-(4-methylpiperazin-1-yl)benzo[b][1,4]benzothiazepine has certain solubility trends in different solvents, its overall hydrophobic nature poses challenges in aqueous solutions, making it necessary to consider specific conditions for optimal dissolution.