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8-Fluorooctan-1-amine

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Identification
Molecular formula
C8H18FN
CAS number
459-57-4
IUPAC name
8-fluorooctan-1-amine
State
State

At room temperature, 8-fluorooctan-1-amine is typically a liquid. It flows easily and is not susceptible to immediate evaporation under normal atmospheric conditions, reflecting its medium volatility relative to typical organic amines of similar size.

Melting point (Celsius)
-18.00
Melting point (Kelvin)
255.20
Boiling point (Celsius)
212.50
Boiling point (Kelvin)
485.60
General information
Molecular weight
147.24g/mol
Molar mass
147.2260g/mol
Density
0.9052g/cm3
Appearence

8-Fluorooctan-1-amine is a colorless to pale yellow liquid. It may have a characteristic amine-like odor and can appear clear when purified. In its impure form, it may have a slightly hazy appearance.

Comment on solubility

Solubility of 8-fluorooctan-1-amine

8-fluorooctan-1-amine, with the chemical formula C8H18FN, exhibits interesting solubility characteristics due to its unique structure. Solubility is greatly influenced by the functional groups present and the overall hydrophobic or hydrophilic nature of a compound. In the case of 8-fluorooctan-1-amine:

  • Aromatic Nature: The presence of the fluorine atom adds a degree of polarity, which may enhance solubility in polar solvents.
  • Aliphatic Hydrocarbon Chain: The long hydrophobic octyl group typically makes the compound less soluble in water but more soluble in organic solvents.
  • Amine Group: The amine functional group can form hydrogen bonds, aiding solubility in polar solvents, especially in alcohols.

Overall, you could expect 8-fluorooctan-1-amine to be:

  1. **Slightly soluble in water** due to the amine group capabilities.
  2. **More soluble in organic solvents** like ethanol, acetone, or chloroform.

In summary, the solubility of 8-fluorooctan-1-amine showcases the balance between its hydrophobic and hydrophilic characteristics, leading to its preference for organic solvents while displaying modest solubility in water.

Interesting facts

Interesting Facts about 8-Fluorooctan-1-amine

8-Fluorooctan-1-amine is a fascinating compound with unique properties and significance in various fields. Here are some intriguing insights:

  • Fluorine Substitution: The presence of fluorine in this compound can significantly influence its chemical reactivity and biological activity. Fluorine is known for enhancing lipophilicity, which can aid in the permeability of the compound through biological membranes.
  • Applications in Medicinal Chemistry: Compounds like 8-fluorooctan-1-amine are often explored for their potential in drug development. Fluorinated compounds are frequently found in pharmaceuticals due to their improved metabolic stability and the ability to modulate biological interactions.
  • Role in Agrochemicals: Similar fluorinated compounds are studied for their effects on pest control and agricultural practices. Their unique properties can help in the design of more effective agrochemicals with reduced environmental impact.
  • Industrial Uses: This compound may have potential applications in the synthesis of various materials, including polymers and specialty chemicals. Fluorinated compounds are often utilized in industries seeking stability and performance under diverse conditions.
  • Research Opportunities: The study of 8-fluorooctan-1-amine opens avenues for research into its interactions and efficacy through various chemical pathways. Understanding its behavior in biological systems can contribute greatly to advancements in medicinal chemistry.

In summary, 8-fluorooctan-1-amine exemplifies the significance of fluorinated compounds in scientific innovation. As research continues to unveil the potential of such compounds, they remain a critical focus in chemistry, pharmaceuticals, and beyond.

Synonyms
8-Fluorooctylamine
593-16-8
OCTYLAMINE, 8-FLUORO-
BRN 1735430
DTXSID00208024
4-04-00-00762 (Beilstein Handbook Reference)
DTXCID20130515
8-fluorooctan-1-amine
SCHEMBL2501735
AKOS006364248
EN300-7639100