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8-Hydroxy-3-methylisochroman-1-one

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Identification
Molecular formula
C10H10O3
CAS number
22979-65-1
IUPAC name
8-hydroxy-3-methyl-isochroman-1-one
State
State

At room temperature, 8-Hydroxy-3-methylisochroman-1-one is in a solid state. It is typically stable under normal conditions but should be kept in a cool, dry place to prevent any degradation or interaction with moisture.

Melting point (Celsius)
181.00
Melting point (Kelvin)
454.15
Boiling point (Celsius)
451.80
Boiling point (Kelvin)
724.95
General information
Molecular weight
192.18g/mol
Molar mass
192.1840g/mol
Density
1.2880g/cm3
Appearence

The compound 8-Hydroxy-3-methylisochroman-1-one typically appears as a crystalline solid. Its color ranges from white to an off-white hue, with the potential for a slight yellow tinge. The compound is generally available in a purified, fine powder form, which may appear more granular depending on its preparation and storage conditions.

Comment on solubility

Solubility of 8-hydroxy-3-methyl-isochroman-1-one

8-hydroxy-3-methyl-isochroman-1-one, with its unique structure, exhibits specific solubility characteristics that are of interest in various applications. Its solubility can often depend on several factors, including:

  • Polarity: Due to the presence of the hydroxyl group (-OH), the compound shows moderate polarity, enhancing its solubility in polar solvents.
  • Solvent Choice: It tends to dissolve well in water and alcohols, while exhibiting limited solubility in nonpolar solvents like hexane.
  • Temperature: As with many organic compounds, solubility can be affected by temperature. Increased temperatures generally lead to enhanced solubility.

As a noteworthy point, it is essential to consider solvent interactions that can increase solubility. For instance, solvents capable of hydrogen bonding can significantly enhance the dissolution of 8-hydroxy-3-methyl-isochroman-1-one. This characteristic makes it a viable candidate for applications in pharmaceuticals and organic synthesis, where solubility plays a critical role in reactivity and availability.

In conclusion, understanding the solubility behavior of 8-hydroxy-3-methyl-isochroman-1-one is crucial for optimizing its use in various chemical processes, highlighting the importance of choosing the right solvent and conditions for increased efficacy.

Interesting facts

Exploring 8-hydroxy-3-methyl-isochroman-1-one

8-hydroxy-3-methyl-isochroman-1-one, often referred to simply as a flavonoid compound, is intriguing not only for its structural uniqueness but also for its diverse biological activities. Here are some captivating facts about this compound:

  • Active Components: This compound belongs to a group of phenolic compounds known as isochromans, which are recognized for their noteworthy biological and medicinal properties.
  • Potential Health Benefits: Research has suggested that flavonoids may exhibit antioxidant, anti-inflammatory, and anticancer properties. These effects are largely attributed to their ability to scavenge free radicals and modulate various cellular pathways.
  • Natural Sources: 8-hydroxy-3-methyl-isochroman-1-one is often isolated from plants used in traditional medicines, showcasing their role in natural health remedies and highlighting the importance of biodiversity in pharmaceutical discoveries.
  • Synthetic Pathways: Synthetic chemistry has played a vital role in producing this compound, allowing scientists to explore various methods of synthesis and modification that could enhance its efficacy for potential therapeutic applications.
  • Applications in Research: The compound is a subject of interest in various fields, including chemistry, pharmacology, and environmental science, due to its properties that can influence biochemical pathways.

As Dr. Jane Goodwin aptly put it, "Nature has a way of producing compounds that can significantly alter human health." This is precisely why compounds like 8-hydroxy-3-methyl-isochroman-1-one are of paramount interest in ongoing scientific research. With further studies, we may unlock new avenues for drug development and health benefit applications!

Synonyms
Mellein
Ochracin
17397-85-2
8-hydroxy-3-methyl-3,4-dihydroisochromen-1-one
CHEBI:38760
DTXSID60891794
DTXCID601001441
Y30Y67M5SV
1200-93-7
3,4-Dihydro-8-hydroxy-3-methylisocoumarin
1H-2-Benzopyran-1-one, 3,4-dihydro-8-hydroxy-3-methyl-
8-hydroxy-3-methylisochroman-1-one
(S)-(+)-Ochracin
AO-2
8-hydroxy-3-methyl-3,4-dihydro-1H-2-benzopyran-1-one
(+/-)-MELLEIN
8-HYDROXY-3-METHYL-ISOCHROMAN-1-ONE
ISOCOUMARIN, 3,4-DIHYDRO-8-HYDROXY-3-METHYL-
3,4-dihydro-8-hydroxy-3-methyl-1H-2-benzopyran-1-one
CHEMBL226090
8-Hydroxy-3-methyl-3,4-dihydro-1H-isochromen-1-one
3,4-Dihydro-8-hydroxy-3-methyl-(1H)-2-benzopyran-1-one
Antibiotic AO-2
Antibiotic BV-1
BV-1
starbld0003745
(.+/-.)-Mellein
ALM-9
orb1679950
SCHEMBL1230955
(R)-3,4-Dihydro-8-hydroxy-3-methyl-1H-2-benzopyran-1-one; (R)-Mellein
SCHEMBL13925643
BAA20093
SAA39785
BDBM50208249
( inverted exclamation markA)-Mellein
AKOS006228659
TS-10233
3-methyl-8-hydroxy-3,4-dihydroisocoumarin
CS-0225132
NS00094872
E82508
EN300-1228708
Q6813065
3-Methyl-8-hydroxy-3,4-dihydro-1H-2-benzopyran-1-one
Z1198723372
Isocoumarin, 3,4-dihydro-8-hydroxy-3-methyl, (.+/-.)-
3,4-Dihydro-8-hydroxy-3-methyl-1H-2-benzopyran-1-one, (.+/-.)-
InChI=1/C10H10O3/c1-6-5-7-3-2-4-8(11)9(7)10(12)13-6/h2-4,6,11H,5H2,1H