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Carteolol

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Identification
Molecular formula
C16H24N2O3
CAS number
51781-06-7
IUPAC name
8-hydroxy-5-[1-hydroxy-2-(isopropylamino)butyl]-1H-quinolin-2-one
State
State

Carteolol is typically found in a solid state at room temperature. When formulated as its hydrochloride salt for ophthalmic use, it is often presented in liquid form as eye drops.

Melting point (Celsius)
244.00
Melting point (Kelvin)
517.15
Boiling point (Celsius)
530.60
Boiling point (Kelvin)
803.75
General information
Molecular weight
292.38g/mol
Molar mass
292.3610g/mol
Density
1.1875g/cm3
Appearence

Carteolol appears as a white or off-white crystalline powder. It is odorless and usually used in ophthalmic solutions in its hydrochloride salt form.

Comment on solubility

Solubility of 8-hydroxy-5-[1-hydroxy-2-(isopropylamino)butyl]-1H-quinolin-2-one (C16H24N2O3)

The solubility of 8-hydroxy-5-[1-hydroxy-2-(isopropylamino)butyl]-1H-quinolin-2-one in various solvents can be quite intriguing due to its unique chemical structure. Here are some key points regarding its solubility:

  • Polarity: The presence of hydroxyl groups (-OH) suggests that the compound may exhibit mixed polarity characteristics, potentially making it soluble in both polar and non-polar solvents.
  • Hydrogen Bonding: Its ability to form hydrogen bonds can enhance solubility in polar solvents such as water.
  • Organic Solvents: It is likely to be soluble in organic solvents such as methanol, ethanol, or dichloromethane due to its slightly hydrophobic aromatic ring structure.
  • Practical Applications: Understanding solubility is essential for its application in pharmaceutical formulations, where a balance between solubility and stability is crucial.

Overall, while predicting solubility can be complex, the features of this compound suggest it may present a favorable solubility profile in a range of solvents. As always, experimental verification of solubility in specific solvents is recommended for practical applications.

Interesting facts

Interesting Facts about 8-Hydroxy-5-[1-Hydroxy-2-(isopropylamino)butyl]-1H-quinolin-2-one

8-Hydroxy-5-[1-hydroxy-2-(isopropylamino)butyl]-1H-quinolin-2-one is a fascinating chemical compound with a range of potential applications, particularly in the field of medicinal chemistry. Here are some intriguing aspects of this compound:

  • Quinoline Derivative: This compound is a derivative of quinoline, a class of compounds known for their varied biological activities, including anti-inflammatory and antimicrobial properties.
  • Potential Therapeutic Uses: Compounds with similar structures have been explored for their ability to treat conditions such as cancer, cardiovascular diseases, and neurological disorders.
  • Hydroxyl Group Influence: The presence of hydroxyl groups in its structure enhances its solubility in water and can significantly influence its biological activity by facilitating interactions with enzymes and receptors in the body.
  • Isopropylamino Substituent: The isopropylamino moiety adds steric bulk, which can modify the compound's pharmacokinetics, potentially improving its efficacy and reducing side effects.
  • Research Interest: Ongoing research focuses on the synthesis and modification of similar quinoline derivatives to optimize their therapeutic profiles and explore new applications in drug discovery.

This compound exemplifies the rich potential found within the world of organic chemistry, where slight modifications in molecular structure can lead to vastly different properties and applications. As researchers continue to explore the medicinal capabilities of quinoline derivatives, compounds like this one may pave the way for innovative treatments in the future.

Synonyms
PROCATEROL
60443-17-6
72332-33-3
Pro-Air
8-hydroxy-5-[1-hydroxy-2-(propan-2-ylamino)butyl]-1H-quinolin-2-one
Procaterolo
Meptin
NSC308904
(R*,S*)-(-)-8-Hydroxy-5-(1-hydroxy-2-((1-methylethyl)amino)butyl)-2(1H)-quinolinone
Procaterol (INN)
NSC 308904
NSC-308904
Spectrum2_001550
Spectrum3_001770
2(1H)-Quinolinone, 8-hydroxy-5-(1-hydroxy-2-((1-methylethyl)amino)butyl)-
8-Hydroxy-5-(1-hydroxy-2-((1-methylethyl)amino)butyl)-2(1H)-quinolinone
SCHEMBL4632
BSPBio_003239
SPBio_001400
CHEMBL160519
GTPL3464
CHEBI:91585
KBio3_002739
DTXSID50860939
5-[1-hydroxy-2-(propan-2-ylamino)butyl]quinoline-2,8-diol
XCA33233
BDBM50493310
STK632659
AKOS005564627
AKOS015961460
NCGC00018291-02
NCGC00024381-02
AC-13705
DB-055628
DB-229702
NS00096927
D08424
L023776
BRD-A22684332-003-02-3
BRD-A22684332-003-03-1
Q27088451
5-(1-hydroxy-2-isopropylaminobutyl)-8-hydroxycarbostyril
8-Hydroxy-5-{1-hydroxy-2-[(propan-2-yl)amino]butyl}quinolin-2(1H)-one