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Ibogaine hydrochloride

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Identification
Molecular formula
C20H26ClN3O
CAS number
89257-92-5
IUPAC name
8-methoxy-1,2,3,4,5,6-hexahydroazepino[4,5-b]indol-6-ium;chloride
State
State

In its pure form, ibogaine hydrochloride is a crystalline solid at room temperature. It is usually manipulated in research and therapeutic contexts in its solid state, but it can be dissolved in solution for pharmacological use.

Melting point (Celsius)
282.00
Melting point (Kelvin)
555.00
Boiling point (Celsius)
300.00
Boiling point (Kelvin)
573.00
General information
Molecular weight
356.90g/mol
Molar mass
356.2300g/mol
Density
1.4100g/cm3
Appearence

Ibogaine hydrochloride is typically a white to off-white crystalline powder. It is known for its matte texture, which can appear slightly granular depending on the conditions of crystallization.

Comment on solubility

Solubility Overview of 8-Methoxy-1,2,3,4,5,6-hexahydroazepino[4,5-b]indol-6-ium Chloride

The solubility of 8-methoxy-1,2,3,4,5,6-hexahydroazepino[4,5-b]indol-6-ium chloride in various solvents can provide significant insights into its chemical behavior and potential applications. The presence of the methoxy group and the 6-ium cation in its structure suggests a tendency to interact well with polar solvents, primarily due to ionic and dipole-dipole interactions.

Factors Influencing Solubility

  • Polarity: The ionic nature of the chloride enhances solubility in polar solvents like water and methanol.
  • Hydrogen Bonding: The potential for hydrogen bonding contributes to its solubility, making it likely to dissolve in solvent systems that can donate or accept hydrogen bonds.
  • Temperature: Elevated temperatures may generally improve solubility for many ionic compounds; thus, it is beneficial to consider temperature variations during solubility assessments.

In conclusion, while specific numerical solubility data may vary, it is anticipated that 8-methoxy-1,2,3,4,5,6-hexahydroazepino[4,5-b]indol-6-ium chloride will show appreciable solubility in polar solvents due to its structural characteristics. This solubility can be pivotal for its application in synthesis and medicinal chemistry.

Interesting facts

Interesting Facts about 8-Methoxy-1,2,3,4,5,6-hexahydroazepino[4,5-b]indol-6-ium;chloride

8-Methoxy-1,2,3,4,5,6-hexahydroazepino[4,5-b]indol-6-ium;chloride is an intriguing compound that boasts a unique structure and several fascinating properties. Below are some thought-provoking aspects of this compound:

  • Structural Complexity: The presence of both azepine and indole rings in its structure leads to intriguing chemical behavior and interactions. The fusion of these two ring systems creates a compound that is central in various chemical studies.
  • Potential Applications: Due to its structural features, this compound may have potential applications in medicinal chemistry, particularly in the design of new pharmaceutical agents. Its unique configuration might provide insights into drug development.
  • Electrophilic Behavior: The nitrogen atoms within the azepine moiety can act as nucleophiles, making this compound interesting for organic synthesis. Its reactivity can be explored in pathways leading to more complex molecules.
  • Bioactivity: Research on related compounds has shown that indole derivatives can exhibit various biological activities, including antibacterial and anticancer properties. The bioactive potential of this compound could stimulate further research.
  • Interdisciplinary Interest: This compound attracts attention not only from chemists but also from pharmacologists and material scientists, showcasing the interconnected nature of modern science.

To summarize, 8-Methoxy-1,2,3,4,5,6-hexahydroazepino[4,5-b]indol-6-ium;chloride is a remarkable compound that highlights the intricate relationships between structure, reactivity, and potential applications in science and medicine. As further studies unfold, the true value of this compound may become even more significant.

Synonyms
1,2,3,4,5,6-Hexahydro-8-methoxy-azepino(4,5-b)indole hydrochloride
15918-71-5
AZEPINO(4,5-b)INDOLE, 1,2,3,4,5,6-HEXAHYDRO-8-METHOXY-, MONOHYDROCHLORIDE