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Identification
Molecular formula
C19H11NO8
CAS number
19992-70-6
IUPAC name
8-methoxy-6-nitro-naphtho[2,1-g][1,3]benzodioxole-5-carboxylic acid
State
State

At room temperature, this compound is a solid.

Melting point (Celsius)
210.00
Melting point (Kelvin)
483.15
Boiling point (Celsius)
556.00
Boiling point (Kelvin)
829.15
General information
Molecular weight
387.29g/mol
Molar mass
387.2890g/mol
Density
1.6718g/cm3
Appearence

The compound typically appears as a crystalline solid. It may be encountered as a colorless or pale yellow solid depending on purity and form.

Comment on solubility

Solubility of 8-Methoxy-6-nitro-naphtho[2,1-g][1,3]benzodioxole-5-carboxylic Acid

The solubility of 8-methoxy-6-nitro-naphtho[2,1-g][1,3]benzodioxole-5-carboxylic acid (C19H11NO8) can be fascinating due to its complex structure. This compound is likely to exhibit varying solubility characteristics depending on the solvent used. Key points to consider include:

  • Polarity: The presence of multiple functional groups, including a carboxylic acid, suggests that the compound may be more soluble in polar solvents such as water or methanol.
  • Hydrogen Bonding: The carboxylic acid group can engage in hydrogen bonding, further enhancing its solubility in polar environments.
  • Aromatic Nature: The extensive aromatic character can lead to lower solubility in non-polar solvents due to π-π stacking interactions.
  • pH Dependence: The solubility may also vary with pH, influenced by the ionization of the carboxylic acid group.

Overall, the solubility of this compound is characterized by the competition between its hydrophobic aromatic sections and its hydrophilic functional groups. As one expert noted, “solubility is the dance between structure and solvent,” highlighting the intricate relationship between a compound's architecture and its interaction with potential solvents.

In conclusion, understanding the solubility of 8-methoxy-6-nitro-naphtho[2,1-g][1,3]benzodioxole-5-carboxylic acid requires consideration of multiple factors including polarity, hydrogen bonding, and the influence of solvent choice.

Interesting facts

Interesting Facts about 8-methoxy-6-nitro-naphtho[2,1-g][1,3]benzodioxole-5-carboxylic acid

The intriguing compound 8-methoxy-6-nitro-naphtho[2,1-g][1,3]benzodioxole-5-carboxylic acid, known for its complex structure, belongs to a family of compounds that has shown significant promise in various fields, particularly in medicinal chemistry. Here are some fascinating insights:

  • Structural Complexity: This compound features a hybrid structure combining elements of naphthalene and benzodioxole, leading to its distinctive chemical behavior and reactivity.
  • Pharmacological Potential: Many derivatives of compounds similar to this one have exhibited anti-inflammatory and anticancer activities, highlighting the potential of this class of compounds in therapeutic applications.
  • Introduction of Functional Groups: The presence of both methoxy and nitro groups enhances the compound's ability to participate in various chemical reactions, making it a versatile candidate for further research and development.
  • Unique Reactivity: Its aromatic system allows for electrophilic aromatic substitutions, enabling it to undergo transformations that could yield new derivatives with tailored properties.
  • Applications in Materials Science: Compounds like this one are explored for their potential to be integrated into organic semiconductors or as part of novel polymer materials due to their electronic properties.

As scientists delve deeper into the study of such compounds, it is essential to explore their synthesis, reactivity, and potential applications. Research in this area could lead to breakthroughs in drug discovery and material sciences, paving the way for innovative solutions to prevalent challenges.

"The beauty of chemistry lies in the diverse functionalities of compounds that can lead to unexpected discoveries."

Synonyms
Aristolochic acid
Aristolochic acid A
313-67-7
Aristolochic acid I
Tardolyt
Aristolochin
Aristolochic acid-I
Birthwort
ARISTOLOCHINE
TR 1736
Aristolochiazaeure
NSC-50413
Aristolochic acid 1
8-Methoxy-6-nitrophenanthro[3,4-d][1,3]dioxole-5-carboxylic acid
CCRIS 1544
NSC11926
EINECS 206-238-3
3,4-Methylenedioxy-8-methoxy-10-nitro-1-phenanthrenecarboxylic acid
NSC 11926
NSC 50413
UNII-94218WFP5T
BRN 0345159
CHEBI:2825
ARISTOLOCHIA A
8-Methoxy-6-nitrophenanthol (3,4-d) 1,3-dioxole-5-carboxylic acid
94218WFP5T
NSC50413
MFCD00004996
NSC-11926
8-Methoxy-3,4-methylenedioxy-10-nitrophenanthrene-1-carboxylic acid
8-methoxy-6-nitronaphtho[2,1-g][1,3]benzodioxole-5-carboxylic acid
Phenanthro(3,4-d)-1,3-dioxole-5-carboxylic acid, 8-methoxy-6-nitro-
CHEMBL93353
MLS002702976
Aristolochic acid I;TR 1736
DTXSID0040969
8-Methoxy-3,4-methylendioxxy-10-nitro-1-phenanthrencarbonsaeure
8-methoxy-6-nitrophenanthro(3,4-d)-1,3-dioxole-5-carboxylic acid
Phenanthro[3,4-d]-1,3-dioxole-5-carboxylic acid, 8-methoxy-6-nitro-
TR-1736
2-Naphthyl Pyrovalerone-d8 Hydrochloride
1246815-48-4
ARISTOLOCHIC ACID (IARC)
ARISTOLOCHIC ACID [IARC]
C17H11NO7
8-methoxy-6-nitro-naphtho[1,2-e][1,3]benzodioxole-5-carboxylic acid
SMR001562128
SR-05000002369
ARISTOLOCHIC ACID, PLANTS CONTAINING (IARC)
ARISTOLOCHIC ACID, PLANTS CONTAINING [IARC]
Aristolochia
Phenanthro[3,3-dioxole-5-carboxylic acid, 8-methoxy-6-nitro-
8-methoxy-6-nitrophenanthro(3,4-d)(1,3)dioxole-5-carboxylic acid
AristolochicacidA
aris-tolochic acid
1-(Naphthalen-2-yl)-2-(pyrrolidin-1-yl-d8)pentan-1-one Hydrochloride; 1-(2-Naphthalenyl)-2-(1-pyrrolidinyl-d8)-1-pentanone-d8 Hydrochloride; Naphyrone-d8 Hydrochloride
GOQ
Aristolochic-acid-A
Spectrum_001156
SpecPlus_000448
Spectrum2_000822
Spectrum3_001114
Spectrum4_001952
Spectrum5_000729
Aristolochic acid A,(S)
NCIMech_000812
Aristolochic acid I, powder
BSPBio_001440
BSPBio_002848
KBioGR_000160
KBioGR_002387
KBioSS_000160
KBioSS_001636
MLS002695974
DivK1c_006544
SCHEMBL166284
SPECTRUM1502233
SPBio_000743
ARISTOLOCHIC ACID [MI]
Aristolochic acid A (Standard)
DTXCID8020969
GTPL12438
HY-N0510R
KBio1_001488
KBio2_000160
KBio2_001636
KBio2_002728
KBio2_004204
KBio2_005296
KBio2_006772
KBio3_000319
KBio3_000320
KBio3_002068
Bio1_000418
Bio1_000907
Bio1_001396
Bio2_000160
Bio2_000640
HMS1361H22
HMS1791H22
HMS1989H22
HMS3402H22
ARISTOLOCHIC ACID [WHO-DD]
HY-N0510
TNP00273
8-methoxy-6-nitro-naphtho[2,1-g][1,3]benzodioxole-5-carboxylic acid
BDBM50306855
CCG-35796
CCG-36162
NSC787054
s9193
Mixture of Aristolochic Acid A and B
AKOS015896751
FA17982
NSC-787054
IDI1_033910
NCGC00017334-01
NCGC00017334-02
NCGC00017334-03
NCGC00017334-04
NCGC00017334-05
NCGC00017334-06
NCGC00017334-07
NCGC00095981-01
NCGC00095981-02
NCGC00095981-03
NCGC00095981-04
NCGC00095981-05
1ST40180
AC-34489
Aristolochic acid - Mixture of I and II
BS-16911
NCI60_000460
XA167153
DB-048017
CS-0009050
NS00003942
C08469
AA-504/21001015
SR-05000002369-2
SR-05000002369-3
Q21099362
Aristolochia, European Pharmacopoeia (EP) Reference Standard
8-Methoxy-6-nitro-phenanthro[3,4-d][1,3]dioxole-5-carboxylic acid
Aristolochic acid I, European Pharmacopoeia (EP) Reference Standard
8-Methoxy-6-nitrophenanthro[3,4-d][1,3]dioxole-5-carboxylic acid #
Phenanthro[3,4-d]-1,3-dioxole-5-carbocylic acid, 8-methoxy-6-nitro-
206-238-3
8-Methoxy-6-nitro-phenanthro[3,4-d]-1,3-dioxole-5-carboxylic acid;Aristolochine;Aristolochia A