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Dantrolene

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Identification
Molecular formula
C14H10N4O3
CAS number
7261-97-4
IUPAC name
8-methyl-1,3-diazaspiro[4.5]decane-2,4-dione
State
State

Solid at room temperature.

Melting point (Celsius)
258.00
Melting point (Kelvin)
531.15
Boiling point (Celsius)
325.00
Boiling point (Kelvin)
598.15
General information
Molecular weight
314.23g/mol
Molar mass
314.2280g/mol
Density
1.3000g/cm3
Appearence

Dantrolene sodium appears as an orange to yellow crystalline powder.

Comment on solubility

Solubility of 8-methyl-1,3-diazaspiro[4.5]decane-2,4-dione

The solubility of 8-methyl-1,3-diazaspiro[4.5]decane-2,4-dione presents an intriguing profile due to its unique molecular structure. This compound contains multiple functional groups and heteroatoms that can influence solubility in various solvents.

Generally, the solubility can be assessed based on some key factors:

  • Polarity: Molecules with polar functional groups tend to be more soluble in polar solvents such as water.
  • Hydrogen Bonding: The presence of nitrogen and carbonyl groups can facilitate hydrogen bonding, enhancing solubility in appropriate solvents.
  • Molecular Size: Larger molecules often exhibit lower solubility in solvent systems due to steric hindrance.

Moreover, it has been observed that:

  • Solubility in Water: The specific combination of nitrogen atoms and the dione functional groups can lead to moderate solubility in water.
  • Organic Solvents: This compound may also exhibit good solubility in organic solvents like ethanol or acetone, where interactions are more favorable.

As a rule of thumb, it’s essential to conduct empirical tests to confirm solubility, as theoretical predictions can sometimes diverge from experimental results.

In summary, the solubility behavior of 8-methyl-1,3-diazaspiro[4.5]decane-2,4-dione is influenced by its molecular properties and the medium of dissolution. Empirical evaluations are essential to accurately define its solubility capabilities.

Interesting facts

Interesting Facts about 8-methyl-1,3-diazaspiro[4.5]decane-2,4-dione

The compound 8-methyl-1,3-diazaspiro[4.5]decane-2,4-dione is a fascinating example of a spirocyclic compound, which boasts unique structural characteristics and potential applications in various fields of research. Here are some interesting insights:

  • Spiro Compounds: This compound belongs to a class of compounds known as spiro compounds. These compounds are defined by having two or more rings that share a single atom, leading to unique geometries and properties.
  • Diversity in Chemistry: The presence of both diazine (two nitrogen atoms in a six-membered ring) and dione (two carbonyl groups) functionalities presents opportunities for diverse chemical reactivity. This can lead to the synthesis of novel derivatives and analogs.
  • Potential Applications: Compounds like 8-methyl-1,3-diazaspiro[4.5]decane-2,4-dione may potentially contribute to drug development due to their structural complexity. Their unique nitrogen-containing framework might exhibit interesting biological activity.
  • Research Interest: The study of spirocyclic compounds and their derivatives is an active area of research, particularly in the context of designing new materials and therapeutic agents. This compound could be of interest to researchers focused on synthetic organic chemistry and medicinal chemistry.
  • Quote from a Chemist: "The beauty of spiro compounds lies in their intricate structures that promise both challenge and opportunity. Each new compound opens a door to the unexplored!"

In summary, 8-methyl-1,3-diazaspiro[4.5]decane-2,4-dione stands at the crossroads of structural elegance and potential utility, embodying the intricate connection between structure and reactivity and capturing the interest of chemists across various disciplines.

Synonyms
8-methyl-1,3-diazaspiro[4.5]decane-2,4-dione
8-Methyl-1,3-diazaspiro(4.5)decane-2,4-dione
969-188-8
707-17-5
MFCD01731592
1,3-DIAZASPIRO(4.5)DECANE-2,4-DIONE, 8-METHYL-
NSC 19565
3-Methylcyclohexanespiro-5'-hydantoin
NSC19565
1,4-dione, 8-methyl-
SCHEMBL7884532
SCHEMBL14609564
SCHEMBL16976708
DTXSID20220965
AAA70717
NSC-19565
AKOS000270798
BS-3995
SY083947
CS-0236367
EN300-17052
G31703
Z56877858
F1909-0047