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Tropicamide

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Identification
Molecular formula
C17H20BrN4O2
CAS number
1508-75-4
IUPAC name
[8-methyl-8-[(4-phenylphenyl)methyl]-8-azoniabicyclo[3.2.1]octan-3-yl] 3-hydroxy-2-phenyl-propanoate
State
State

At room temperature, tropicamide is typically found in a solid state as a crystalline powder. When used in pharmaceutical preparations, it is commonly found in liquid form as an ophthalmic solution.

Melting point (Celsius)
95.00
Melting point (Kelvin)
368.15
Boiling point (Celsius)
225.00
Boiling point (Kelvin)
498.15
General information
Molecular weight
384.51g/mol
Molar mass
384.5140g/mol
Density
1.0203g/cm3
Appearence

Tropicamide appears as a white to off-white crystalline powder. It is odorless and has a bitter taste. The compound is often used in a solution form for ophthalmic applications where clarity and consistency are important.

Comment on solubility

Solubility of 8-methyl-8-[(4-phenylphenyl)methyl]-8-azoniabicyclo[3.2.1]octan-3-yl 3-hydroxy-2-phenyl-propanoate

The solubility of complex organic compounds like 8-methyl-8-[(4-phenylphenyl)methyl]-8-azoniabicyclo[3.2.1]octan-3-yl 3-hydroxy-2-phenyl-propanoate can be quite variable and depends on several factors:

  • Polarity: This compound demonstrates notable structural complexity with hydrophobic phenyl groups that can hinder solubility in polar solvents. Conversely, the azoniabicyclo structure may impart some interaction with polar media.
  • Temperature: Like most organic compounds, solubility can increase with temperature. As temperature rises, molecular motion increases, improving the solvation of this compound in various solvents.
  • Solvent Choice: The choice of solvent plays a crucial role. It is likely to be more soluble in organic solvents like ethanol or chloroform than in water due to its hydrocarbon content.
  • Concentration: Increased concentration can lead to saturation, beyond which no further dissolution occurs, forming a precipitate.

In summary, understanding the solubility of this compound requires careful consideration of its unique chemical structure and the nature of the solvent used. Although solubility may be limited in aqueous environments, exploring various organic solvents could unveil its potential for use in numerous applications.

Interesting facts

Interesting Facts about 8-methyl-8-[(4-phenylphenyl)methyl]-8-azoniabicyclo[3.2.1]octan-3-yl 3-hydroxy-2-phenyl-propanoate

This compound is a fascinating example of complex organic chemistry, showcasing the intricate relationship between structure and function in chemical compounds. Here are some interesting insights:

  • Unique Structure: The presence of a bicyclic structure enhances its stability and reactivity, allowing it to participate in a variety of chemical reactions.
  • Medical Potential: Compounds with quaternary ammonium structures, like this one, have been investigated for use as pharmaceuticals. They may exhibit properties beneficial for *antimicrobial* and *antifungal* applications.
  • Chirality: The compound's molecular architecture allows for potential chiral centers, making it an interesting subject for studies in asymmetric synthesis and stereochemistry.
  • Applications in Materials Science: Its unique features may be valuable in the development of novel materials, especially in the fields of sensors and drug delivery systems.
  • Interdisciplinary Connections: The exploration of such complex compounds highlights the interplay between organic chemistry, medicinal chemistry, and materials science, making it a rich topic for research and discussion.

As you dive deeper into the study of this compound, remember the words of renowned chemist Linus Pauling: "The best way to have a good idea is to have a lot of ideas." This compound exemplifies the creativity and complexity inherent in chemical research.
Embrace the challenge of understanding its synthesis, reactivity, and potential applications!

Synonyms
4-Biphenylmethyl-(tropyl-alpha-tropinium)
DTXSID80862082
38971-12-9
8-[([1,1'-Biphenyl]-4-yl)methyl]-3-[(3-hydroxy-2-phenylpropanoyl)oxy]-8-methyl-8-azabicyclo[3.2.1]octan-8-ium