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Scopolamine hydrobromide

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Identification
Molecular formula
C17H22NO4 · HBr
CAS number
6533-68-2
IUPAC name
(8-methyl-8-azabicyclo[3.2.1]octan-3-yl) 3-hydroxy-2-phenyl-propanoate;hydrobromide
State
State

At room temperature, scopolamine hydrobromide is typically in a solid state. It is usually supplied as a powder for pharmaceutical uses or in a solution for injections.

Melting point (Celsius)
194.00
Melting point (Kelvin)
467.15
Boiling point (Celsius)
0.00
Boiling point (Kelvin)
0.00
General information
Molecular weight
384.28g/mol
Molar mass
0.0000g/mol
Density
1.5900g/cm3
Appearence

Scopolamine hydrobromide appears as a white or off-white crystalline powder. It is hygroscopic and should be stored in a tightly sealed container to prevent absorption of moisture from the air.

Comment on solubility

Solubility Characteristics of (8-methyl-8-azabicyclo[3.2.1]octan-3-yl) 3-hydroxy-2-phenyl-propanoate; hydrobromide

The solubility of a compound can significantly influence its applications and effectiveness, especially in biological systems. For the compound (8-methyl-8-azabicyclo[3.2.1]octan-3-yl) 3-hydroxy-2-phenyl-propanoate; hydrobromide, several key points regarding its solubility are worth noting:

  • Hydrobromide salt formation: The presence of the hydrobromide indicates that this compound may exhibit enhanced solubility in polar solvents, particularly water. Salts often have improved aqueous solubility compared to their neutral counterparts.
  • Polarity: The functional groups present, such as hydroxy and phenyl groups, contribute to the polarity of the molecule. This can facilitate solubility in various organic solvents, along with water.
  • Temperature dependence: Like many organic compounds, solubility may increase with temperature. Thus, dissolution may be optimized at elevated temperatures.
  • pH Influence: The solubility characteristics may vary with pH, as the ionization state of the hydroxy functional group can change in different pH environments.

In summary, the solubility of (8-methyl-8-azabicyclo[3.2.1]octan-3-yl) 3-hydroxy-2-phenyl-propanoate; hydrobromide is anticipated to be quite favorable in aqueous solutions, though behavior in non-polar or less polar solvents may differ significantly. Understanding these solubility attributes is crucial for its practical usage and formulation in pharmaceutical applications.

Interesting facts

Interesting Facts about (8-methyl-8-azabicyclo[3.2.1]octan-3-yl) 3-hydroxy-2-phenyl-propanoate; hydrobromide

This compound, often used in the pharmaceutical industry, demonstrates the fascinating complexity and diversity of organic chemistry. Known for its unique bicyclic structure, it embodies a variety of interesting attributes:

  • Medicinal Significance: The presence of the bicyclic system allows for potential applications in drug design. Compounds with similar structures are known to exhibit significant biological activity, making them valuable in therapeutics.
  • Synthetic Challenges: The synthesis of such a compound can be quite intricate, often requiring various steps and careful control of reaction conditions. This presents a stimulating challenge for chemists.
  • Structure-Activity Relationship: Understanding how variations in the two moieties impact biological activity can lead to new derivatives with improved efficacy or fewer side effects. This opens avenues for innovative pharmaceutical research.
  • Research Applications: The compound's hydrobromide form may enhance its solubility, potentially broadening its application in various biochemical assays.

As noted by many researchers, "The complexity of these organic molecules not only serves as a testament to the creativity of chemistry but also highlights the potential benefits they can bring to human health."
This compound is a perfect representation of how every atom and bond contributes to the overall functionality and efficacy of a molecule.

In summary, (8-methyl-8-azabicyclo[3.2.1]octan-3-yl) 3-hydroxy-2-phenyl-propanoate; hydrobromide exemplifies the blend of molecular complexity and practical application that characterizes the field of medicinal chemistry.

Synonyms
HYOSCYAMINE HYDROBROMIDE
306-03-6
(8-Methyl-8-azabicyclo[3.2.1]octan-3-yl) (2S)-3-hydroxy-2-phenylpropanoate;hydrobromide
(8-methyl-8-azabicyclo[3.2.1]octan-3-yl) 3-hydroxy-2-phenylpropanoate;hydrobromide
Daturine (hydrobromide)
L-Hyoscyamine (hydrobromide)
Hyoscyaminhydrobromid
()-hyoscyamine hydrobromide
SCHEMBL5025985
DTXSID60982651
H0451
8-Methyl-8-azabicyclo[3.2.1]octan-3-yl 3-hydroxy-2-phenylpropanoate--hydrogen bromide (1/1)