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Mitomycin C

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Identification
Molecular formula
C15H18N4O5
CAS number
50-07-7
IUPAC name
8,12,14-trihydroxy-5-methyl-11,13-bis(methylamino)-2,4,9-trioxatricyclo[8.4.0.03,8]tetradecan-7-one
State
State

At room temperature, Mitomycin C is a solid with a crystalline structure. It is usually supplied as a powder for pharmaceutical uses.

Melting point (Celsius)
360.00
Melting point (Kelvin)
633.15
Boiling point (Celsius)
0.00
Boiling point (Kelvin)
0.00
General information
Molecular weight
334.33g/mol
Molar mass
334.3340g/mol
Density
1.3000g/cm3
Appearence

Mitomycin C is a pale blue or purple crystalline solid. It may also appear as a bluish-purple powder. This appearance is characteristic of many mitomycin antibiotics, and its distinct coloration can help with identification.

Comment on solubility

Solubility of 8,12,14-Trihydroxy-5-methyl-11,13-bis(methylamino)-2,4,9-trioxatricyclo[8.4.0.03,8]tetradecan-7-one (C15H18N4O5)

The solubility of the compound 8,12,14-trihydroxy-5-methyl-11,13-bis(methylamino)-2,4,9-trioxatricyclo[8.4.0.03,8]tetradecan-7-one is influenced by its complex molecular structure. As a polyhydroxylated compound, it exhibits several intriguing solubility characteristics:

  • Hydrophilicity: Due to the presence of multiple hydroxyl groups (-OH), the compound is likely to exhibit a substantial degree of hydrophilicity, enhancing its solubility in polar solvents such as water.
  • Amine Groups: The bis(methylamino) substitution suggests potential interactions with organic solvents, which may improve solubility in less polar media compared to purely hydrophilic substances.
  • Hydration Capacity: The formation of hydrogen bonds with solvents can significantly increase the compound's solubility, especially in biologically relevant environments.

However, the overall solubility will also depend on factors such as:

  • Temperature: Increased temperature may boost solubility by providing energy to overcome solute-solvent interactions.
  • pH Levels: The ionization state of amine groups can vary with pH, greatly affecting solubility, particularly in aqueous solutions.
  • Concentration of Solvent: The presence of other solutes in a mixture can either inhibit or enhance the solubility through competitive interactions.

In summary, while the theoretical expectation indicates a relatively high solubility for C15H18N4O5 in polar solvents due to its hydroxyl and amine groups, experimental determination is essential for precise characterization. Therefore, evaluating solubility across various conditions is critical for understanding its practical applications.

Interesting facts

Interesting Facts about 8,12,14-Trihydroxy-5-methyl-11,13-bis(methylamino)-2,4,9-trioxatricyclo[8.4.0.03,8]tetradecan-7-one

The compound 8,12,14-trihydroxy-5-methyl-11,13-bis(methylamino)-2,4,9-trioxatricyclo[8.4.0.03,8]tetradecan-7-one is a fascinating example of a complex organic molecule that showcases the rich diversity found within chemical structures. Here are some interesting aspects to consider:

  • Unique Structure: This compound features a tricyclic framework, which is not commonly found in many organic compounds. It exhibits multiple hydroxyl (–OH) groups, making it a polyhydroxy compound that can potentially engage in various hydrogen bonding interactions.
  • Biological Activity: Compounds with multiple hydroxyl and amino groups often possess interesting biological properties. They may act as potential pharmaceuticals or bioactive molecules, impacting metabolic pathways or serving as enzyme inhibitors.
  • Synthetic Intricacy: The synthesis of such a compound poses a significant challenge for organic chemists due to the multiple functional groups and interconnected rings. This complexity not only makes it a candidate for extensive study in synthetic organic chemistry but also highlights the ingenuity required in forming such structures.
  • Research Potential: Compounds with this level of structural sophistication are often the focus of research in drug design and materials science. Their properties may lead to discoveries in medicinal chemistry or serve as precursors for creating new materials with desirable characteristics.

In the words of a well-known chemist, “The beauty of chemistry lies in its complexity. Each compound tells a story, and the more intricate the structure, the more we can learn from it.” This compound exemplifies that sentiment, inviting further exploration into its potential and applications.

As research continues to evolve, the impact of such unique compounds could be substantial, paving the way for innovations in various fields, including pharmaceuticals, materials science, and beyond.

Synonyms
Spectinomicina
8,12,14-trihydroxy-5-methyl-11,13-bis(methylamino)-2,4,9-trioxatricyclo[8.4.0.03,8]tetradecan-7-one
4a,7,9-Trihydroxy-2-methyl-6,8-bis(methylamino)decahydro-4H-pyrano[2,3-b][1,4]benzodioxin-4-one
Actinospectocin
8,12,14-trihydroxy-5-methyl-11,13-bis(methylamino)-2,4,9-trioxatricyclo(8.4.0.03,8)tetradecan-7-one
MLS006011873
SCHEMBL8053238
CHEMBL2009700
DTXSID60859672
UNFWWIHTNXNPBV-UHFFFAOYSA-N
4H-Pyrano[2,3-b][1,4]benzodioxin-4-one, decahydro-4a,7,9-trihydroxy-2-methyl-6,8-bis(methylamino)-, [2R-(2.alpha.,4a.beta.,5a.beta.,6.beta.,7.beta.,8.beta.,9.alpha.,9a.alpha.,10a.beta.)]-
STL018678
AKOS005657254
NCI60_001984
SMR003316686
NS00001800
4a,7,9-Trihydroxy-2-methyl-6,8-bis(methylamino)decahydro-4H-pyrano[2,3-b][1,4]benzodioxin-4-one, [2R-(2.alpha.,4a.beta.,5a.beta.,6.beta.,7.beta.,8.beta.,9.alpha.,9a.alpha.,10a.beta.)]- #