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Scopolamine hydrobromide

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Identification
Molecular formula
C17H24BrNO4
CAS number
114-49-8
IUPAC name
(8,8-dimethyl-8-azoniabicyclo[3.2.1]octan-3-yl) 3-hydroxy-2-phenyl-propanoate;bromide
State
State

At room temperature, scopolamine hydrobromide is in a solid state. It is typically handled as a fine powder.

Melting point (Celsius)
198.00
Melting point (Kelvin)
471.15
Boiling point (Celsius)
225.00
Boiling point (Kelvin)
498.15
General information
Molecular weight
398.33g/mol
Molar mass
398.3340g/mol
Density
1.4900g/cm3
Appearence

Scopolamine hydrobromide appears as a white or slightly off-white crystalline powder. It is odorless, and it's capable of forming transparent and colorless crystals.

Comment on solubility

Solubility Insights

The compound (8,8-dimethyl-8-azoniabicyclo[3.2.1]octan-3-yl) 3-hydroxy-2-phenyl-propanoate; bromide presents intriguing solubility characteristics due to its unique molecular structure. Understanding its solubility can be particularly important for applications in various fields, including pharmaceuticals and materials science.

Solubility Characteristics

Several factors influence the solubility of this compound:

  • Ionic Nature: As a bromide salt, the ionic nature may lead to good solubility in polar solvents like water.
  • Hydrogen Bonding: The presence of the 3-hydroxy group can engage in hydrogen bonding, enhancing solubility in aqueous environments.
  • Hydrophobic Regions: The bulky aromatic ring (phenyl) may create hydrophobic interactions, potentially limiting solubility in very polar solvents.

In practical terms, it is often observed that:

  • This compound is likely soluble in water, forming a stable solution.
  • It may also dissolve in organic solvents, albeit to a lesser extent, due to its hydrophobic features.

In conclusion, the solubility profile of (8,8-dimethyl-8-azoniabicyclo[3.2.1]octan-3-yl) 3-hydroxy-2-phenyl-propanoate; bromide demonstrates the complex interplay between ionic and hydrophobic properties, making its behavior in different solvents an interesting area for further research.

Interesting facts

Interesting Facts about (8,8-dimethyl-8-azoniabicyclo[3.2.1]octan-3-yl) 3-hydroxy-2-phenyl-propanoate; bromide

This fascinating compound, categorized as a quaternary ammonium salt, embodies a rich tapestry of chemical properties and applications. Here are some compelling insights:

  • Structural Significance: The compound's backbone consists of a bicyclic structure, which presents unique stereochemical properties. Such structural characteristics are often linked to enhanced biological activity.
  • Biological Implications: Compounds like these are frequently utilized in medicinal chemistry, targeting various biological pathways. They can serve as intermediates in synthesizing pharmaceuticals, particularly those affecting the central nervous system.
  • Quaternization Effect: The presence of the quaternary ammonium group is pivotal. These groups are known for their ability to interact with biological membranes, potentially leading to increased permeability and bioactivity.
  • Synthetic Utility: The synthetic routes to create such compounds can be quite intricate, often involving multi-step reactions that showcase the versatility of organic synthesis techniques.
  • Application Diversity: Beyond medicinal applications, this compound may also find utility in formulations for surfactants, polymers, and even as a catalyst in certain reactions.

In conclusion, the rich chemistry of (8,8-dimethyl-8-azoniabicyclo[3.2.1]octan-3-yl) 3-hydroxy-2-phenyl-propanoate; bromide not only highlights the complexity of modern organic compounds but also opens exciting avenues for research in both academic and industrial settings. As one might say in the world of chemistry, “Every compound has a story, and this one is both vibrant and multifaceted.”

Synonyms
Mintussin
NSC61810
(8,8-dimethyl-8-azoniabicyclo[3.2.1]octan-3-yl) 3-hydroxy-2-phenylpropanoate;bromide
3-((3-hydroxy-2-phenylpropanoyl)oxy)-8,8-dimethyl-8-azabicyclo[3.2.1]octan-8-ium bromide
ATROPINIUM, 8-METHYL-BROMIDE
3-[(3-HYDROXY-2-PHENYLPROPANOYL)OXY]-8,8-DIMETHYL-8-AZABICYCLO[3.2.1]OCTAN-8-IUM BROMIDE
Atropinium, bromide
SCHEMBL1321572
HMS3260E21
Tox21_500030
CCG-221334
LP00030
NCGC00093550-01
NCGC00260715-01
EU-0100030
A 6883
EN300-312881
WLN: T56 A AKTJ A1 A1 GOVYR&1Q &E
SR-01000075181-2
Z2658866644
8-Azoniabicyclo[3.2.1]octane,8-dimethyl-, bromide, tropate
1.alpha., 3.alpha.-hydroxy-8-methyl-, bromide, (.+-.)-tropate
1.alpha.H, 3.alpha.-hydroxy-8-methyl-, bromide, (.+-.)-tropate
8-Azoniabicyclo[3.2.1]octane,8-dimethyl-, bromide, endo-(.+-.)-
(8,8-dimethyl-8-azoniabicyclo[3.2.1]octan-3-yl) 3-hydroxy-2-phenylpropanoate,bromide
3.alpha.-Hydroxy-8-methyl-1.alpha.,5.alpha.-H-tropanium bromide (.+-.)tropate