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Testosterone

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Identification
Molecular formula
C19H28O2
CAS number
58-22-0
IUPAC name
(8R,9S,10R,13S,14S,17R)-17-hydroxy-10,13-dimethyl-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-one
State
State
At room temperature, testosterone is typically found in a solid state as a crystalline powder.
Melting point (Celsius)
155.00
Melting point (Kelvin)
428.15
Boiling point (Celsius)
383.00
Boiling point (Kelvin)
656.15
General information
Molecular weight
288.42g/mol
Molar mass
288.4240g/mol
Density
1.1200g/cm3
Appearence

Testosterone appears as a white or off-white crystalline powder. It is practically insoluble in water but freely soluble in alcohol.

Comment on solubility

Solubility of (8R,9S,10R,13S,14S,17R)-17-hydroxy-10,13-dimethyl-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-one

The solubility of organic compounds, such as (8R,9S,10R,13S,14S,17R)-17-hydroxy-10,13-dimethyl-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-one, can significantly impact their practical applications and behavior in various environments. Understanding its solubility characteristics is crucial for determining how it interacts with solvents and other substances.

This particular compound is a polycyclic structure, which traditionally influences solubility in the following ways:

  • Polarity: The presence of multiple hydroxyl groups typically enhances solubility in polar solvents like water, due to hydrogen bonding. However, the overall structure suggests a complex balance between polar and non-polar regions.
  • Steric factors: The bulky nature of the compound can impede solvation, particularly in smaller solvents, resulting in lower solubility levels.
  • Temperature dependence: Like many organic compounds, solubility may increase with temperature, permitting greater interaction with solvents.

In summary, while this compound may exhibit some solubility in organic solvents and potentially moderate solubility in polar solvents, factors such as molecular structure, sterics, and temperature interplay to dictate its solubility behavior. Understanding these aspects is essential for successful application in chemical processes and the formulation of solutions.

Interesting facts

Interesting Facts about 17-Hydroxy-10,13-dimethyl-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-one

This compound, commonly known in the field of organic chemistry, fundamentally showcases the intricacies of stereochemistry and molecular structure. Here are some fascinating aspects to consider:

  • Stereoisomerism: The complex configuration signified by the multiple chiral centers in its structure enhances the study of stereoisomerism. Notably, the specific arrangement of atoms can lead to diverse biological activities.
  • Biological Importance: This compound may have implications in the pharmaceutical industry due to its potential biological effects. Compounds with similar structures are often researched for their roles as hormones or therapeutic agents.
  • Natural Occurrence: It is insightful to note that compounds like this can be derived from natural sources. Many steroid-like compounds have biological origins, which adds a layer of significance to studies of this nature.
  • Mechanism of Action: Understanding the active sites and interactions within biological systems can provide crucial insight into how compounds like this influence physiological processes, particularly in hormonal pathways.
  • Research Applications: The detailed study of its molecular interactions can aid in designing analogs that might target specific pathways in diseases such as cancer or endocrine disorders. This aligns with the current trend in medicinal chemistry focusing on tailored therapeutic agents.

The complex nature of 17-hydroxy-10,13-dimethyl-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-one epitomizes the beauty of organic chemistry, making it a compound rich in potential for scientific exploration and discovery.

Synonyms
Epitestosterone
Isotestosterone
481-30-1
cis-Testosterone
17-Epitestosterone
epi-Testosterone
17-alpha-Testosterone
17alpha-Hydroxyandrost-4-en-3-one
17alpha-Testosterone
17.alpha.-Testosterone
NSC 26499
17alpha-cis-Testosterone
Testosterone, cis-
17-alpha-Hydroxyandrost-4-en-3-one
(17-alpha)-17-Hydroxyandrost-4-en-3-one
17.alpha.-Hydroxyandrost-4-en-3-one
BRN 1915396
17a-cis-Testosterone
DTXSID8022329
CHEBI:42534
UNII-48L726977Z
NSC-26499
(8R,9S,10R,13S,14S,17R)-17-hydroxy-10,13-dimethyl-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-one
Androst-4-en-3-one, 17-hydroxy-, (17alpha)-
EPITESTOSTERONE [MI]
Androst-4-en-3-one, 17alpha-hydroxy-
Androst-4-en-3-one, 17.alpha.-hydroxy-
DTXCID002329
48L726977Z
ANDROST-4-EN-3-ONE, 17-alpha-HYDROXY-
4-Androsten-17.alpha.-ol-3-one
17.ALPHA.-CIS-TESTOSTERONE
Androst-4-en-3-one, 17-hydroxy-, (17-alpha)-
Androst-4-en-3-one, 17-hydroxy-, (17.alpha.)-
4-ANDROSTENE-17.ALPHA.-OL-3-ONE
ANDROST-4-EN-17.ALPHA.-OL-3-ONE
TESTOSTERONE IMPURITY C [EP IMPURITY]
17-Hydroxyandrost-4-en-3-one, (17.alpha.)-
TESTOSTERONE IMPURITY C (EP IMPURITY)
17 alpha Testosterone
(8R,9S,10R,13S,14S,17R)-17-hydroxy-10,13-dimethyl-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta(a)phenanthren-3-one
4-Androsten-17alpha-ol-3-one
4-ANDROSTENE-17ALPHA-OL-3-ONE
ANDROST-4-EN-17ALPHA-OL-3-ONE
17-Hydroxyandrost-4-en-3-one, (17alpha)-
Androst-4-en-3-one, 17alpha-hydroxy-(8CI)
mumggozamzwbjj-jzjkzlicsa-n
mumggozamzwbjj-kzyorjdksa-n
17-epi-Testosterone
alpha epitestosterone
(17alpha)-17-hydroxyandrost-4-en-3-one
(10alpha,13alpha,14beta,17alpha)-17-Hydroxyandrost-4-En-3-One
17alpha-Hydroxyandrost-4-en-3-one (Epitestosterone)
NCGC00091018-01
BIDD:ER0485
SCHEMBL334193
CHEMBL196228
NSC26499
Tox21_111058
BDBM50410492
LMST02020051
MSK2266-100A
DB07768
FE22743
Androst-4-en-3-one, (17.alpha.)-
SMP2_000253
NCGC00091018-02
CAS-481-30-1
Epitestosterone 1.0 mg/ml in Acetonitrile
DB-222500
NS00008414
Q416852
Epitestosterone Solution in Acetonitrile, 100ug/mL
BRD-K25836724-001-01-6
(8R,10R,13S,17R)-17-Hydroxy-10,13-dimethyl-1,2,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-cyclopenta[a]phenanthren-3-one