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Testosterone decanoate

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Identification
Molecular formula
C29H46O3
CAS number
5721-91-5
IUPAC name
[(8R,9S,10R,13S,14S,17S)-13-methyl-3-oxo-2,6,7,8,9,10,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl] decanoate
State
State

At room temperature, testosterone decanoate is typically in a solid state as a crystalline powder.

Melting point (Celsius)
45.00
Melting point (Kelvin)
318.15
Boiling point (Celsius)
542.00
Boiling point (Kelvin)
815.15
General information
Molecular weight
442.68g/mol
Molar mass
442.6780g/mol
Density
1.0360g/cm3
Appearence

Testosterone decanoate appears as a white or off-white crystalline powder. It is not soluble in water, but it dissolves in organic solvents like alcohol, chloroform, and ether. It is commonly provided in its crystalline form for pharmaceutical use.

Comment on solubility

Solubility of [(8R,9S,10R,13S,14S,17S)-13-methyl-3-oxo-2,6,7,8,9,10,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl] decanoate

The solubility of this complex compound in various solvents is influenced by its intricate molecular structure. Understanding its solubility characteristics can provide valuable insights for its potential applications. Here are some important points to consider:

  • Polarity: The presence of both hydrophobic alkane chains and polar functional groups suggests that the compound may have limited water solubility.
  • Solvent Interaction: It is likely to be more soluble in organic solvents such as ethanol, methanol, or chloroform due to favorable interactions between the solvent and the carbon backbone.
  • Temperature Dependence: Solubility can vary significantly with temperature; higher temperatures often increase solubility in organic solvents.
  • Concentration Effects: At higher concentrations, solubility can be affected by the presence of other solutes, potentially leading to precipitation in mixed solutions.

In summary, while specific quantitative values for solubility may vary, it is important to emphasize that the solubility of [(8R,9S,10R,13S,14S,17S)-13-methyl-3-oxo-2,6,7,8,9,10,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl] decanoate is expected to be low in water, but significantly greater in non-polar and moderately polar organic solvents. Further experimental studies are essential to define its solubility profile comprehensively.

Interesting facts

Interesting Facts about 13-Methyl-3-oxo-Dodecahydro-Cyclopenta[a]Phenanthren-17-yl Decanoate

This compound, notable for its intricate structure, is part of the class of organic molecules known as steroids, which are renowned for their significance in both biological and synthetic contexts. Here are some intriguing aspects of this compound:

  • Steroidal Framework: The compound exhibits a multi-fused ring system characteristic of steroids. This framework is crucial for its interaction with biological systems, influencing various physiological processes.
  • Biological Relevance: Compounds of similar structures often act as hormones or precursors in metabolic pathways. Their derivatives are widely studied for their roles in growth, metabolism, and reproduction in living organisms.
  • Potential Applications: Due to its steroidal nature, this compound and its derivatives are investigated for their therapeutic potential, particularly in the fields of medicine and pharmacology. They may serve functions in anti-inflammatory therapies or hormonal treatments.
  • Synthesis Challenges: The complex stereochemistry, as indicated by the specific chiral centers in the compound's name, presents challenges for synthesis. Chemists must utilize precise techniques to achieve the correct stereoisomer, which is vital for biological activity.
  • Analytical Techniques: Understanding the structure requires advanced analytical methods. Techniques such as NMR (Nuclear Magnetic Resonance) and mass spectrometry are crucial for determining the compound's configuration and confirming its identity.

In summary, this compound is more than just a chemical entity; it stands at the intersection of chemistry, biology, and medicine. The exploration of such molecules continues to unveil new frontiers in drug development and biological science, making them a focal point for research and innovation.

Synonyms
NANDROLONE DECANOATE
360-70-3
Retabolil
Retabolyl
Nortestosterone decanoate
Deca-Hybolin
Hybolin decanoate
Norandrostenolone decanoate
naboline
Dimapolan
Palactin
Rougerol
Salistoperm
Superbolan
Ziremilon
Anaboline Depot
Anabolin Depot
ndrolone-D
19-Nortestosterone decanoate
Deca-Durabolin
19-Norandrostenolone decanoate
Nandrolone decanoate ciii
DRG 0264
EINECS 206-639-3
Estr-4-en-3-one, 17-[(1-oxodecyl)oxy]-, (17b)-
BRN 2228051
DTXSID7023352
17-beta-Hydroxyestr-4-en-3-one decanoate
UNII-H45187T098
Nandrolone 17beta-decanoate
(17-beta)-17-((1-Oxodecyl)oxy)estr-4-en-3-one
19-NORTESTOSTERONE 17-DECANOATE
CHEBI:7467
DTXCID203352
[(8R,9S,10R,13S,14S,17S)-13-methyl-3-oxo-2,6,7,8,9,10,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl] decanoate
H45187T098
Nandrobolic L.A.
Nandrolone decanoate [USAN:USP:JAN]
Estr-4-en-3-one, 17-((1-oxodecyl)oxy)-, (17beta)-
NCGC00159403-02
17B-HYDROXYESTR-4-EN-3-ONE DECANOATE.
(8R,9S,10R,13S,14S,17S)-13-Methyl-3-oxo-2,3,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl decanoate
Nandrolone Decanoate (~70%)
Estr-4-en-3-one, 17-[(1-oxodecyl)oxy]-, (17.beta.)-
NANDROLONE DECANOATE (MART.)
NANDROLONE DECANOATE [MART.]
Nandrolone decanoate (USAN:USP:JAN)
(1S,2R,10R,11S,14S,15S)-15-methyl-5-oxotetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadec-6-en-14-yl decanoate
CAS-360-70-3
NANDROLONE DECANOATE (EP IMPURITY)
NANDROLONE DECANOATE [EP IMPURITY]
NANDROLONE DECANOATE (EP MONOGRAPH)
NANDROLONE DECANOATE [EP MONOGRAPH]
NANDROLONE DECANOATE CIII (USP-RS)
NANDROLONE DECANOATE CIII [USP-RS]
NANDROLONE DECANOATE (USP MONOGRAPH)
NANDROLONE DECANOATE [USP MONOGRAPH]
17beta-Hydroxyestr-4-en-3-one decanoate
Deca-Durobolin
ESTR-4-EN-3-ONE, 17-((1-OXODECYL)OXY)-, (17.BETA.)-
17beta-Hydroxyestr-4-en-3-one 17-decanoate
Nandrolone decanoate?
Deca-Durabolin (TN)
NANDROLONEDECANOATE
19-Nortestosteron-decanoat
17 beta Hydroxyestr 4 en 3 one 17 decanoate
17 beta-hydroxyestr-4-en-3-one 17-decanoate
Estr-4-en-3-one, 17-beta-hydroxy-, decanoate
SCHEMBL27975
CHEMBL1200946
Nandrolone decanoate (JAN/USP)
NANDROLONE DECANOATE [MI]
NANDROLONE DECANOATE [JAN]
NANDROLONE DECANOATE [USAN]
NANDROLONE DECANOATE [VANDF]
Tox21_111638
NANDROLONE DECANOATE [WHO-DD]
AKOS025311438
Tox21_111638_1
19-Nortestosterone-17.beta.-decanoate
AC-1484
CS-4613
DB08804
GS-3155
NCGC00159403-04
NCGC00263561-01
FN170079
HY-13698
NANDROLONE DECANOATE [ORANGE BOOK]
(17beta)-3-oxoestr-4-en-17-yl decanoate
NS00009587
C08154
D00955
BRD-K78352627-001-01-8
Q16634231
17.BETA.-HYDROXYESTR-4-EN-3-ONE 17-DECANOATE
Nandrolone decanoate, European Pharmacopoeia (EP) Reference Standard
Nandrolone decanoate; Decadurabolin; 17beta-Nandrolone decanoate
Nandrolone decanoate, United States Pharmacopeia (USP) Reference Standard
Nandrolone decanoate for peak identification, European Pharmacopoeia (EP) Reference Standard
Nandrolone decanoate for system suitability, European Pharmacopoeia (EP) Reference Standard
206-639-3