Interesting Facts about (8R,9S,10R,13S,14S,17S)-17-hydroxy-13-methyl-2,6,7,8,9,10,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-one
The compound known as (8R,9S,10R,13S,14S,17S)-17-hydroxy-13-methyl-2,6,7,8,9,10,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-one is a fascinating example of a steroidal structure with significant biological implications.
Biological Importance
- Active Metabolites: This compound is known to function as an important metabolite in various biological systems, influencing hormonal activity.
- Potential Therapeutic Applications: Its structural characteristics lend themselves to possible uses in therapies related to hormonal imbalances, particularly in conditions affecting steroid hormone levels.
- Research in Anti-Cancer Properties: Due to its steroid-like structure, there has been growing interest in studying its effects on cancer cells and exploring its potential as an anti-cancer agent.
Structural Features
The stereochemistry of this compound is particularly interesting, showcasing multiple chiral centers. This contributes to its unique biological activity and interactions with various receptors in the body. The specific configuration is essential in determining how the compound will interact at the molecular level, influencing its pharmacological properties.
Scientific Relevance
In the world of organic chemistry and medicinal chemistry, compounds like this one underscore the importance of chirality and structure-activity relationships (SAR). Understanding how small changes in molecular structure can lead to significant differences in biological activity is a cornerstone of modern drug design.
As a student or researcher, contemplating the implications of such compounds emphasizes the need for detailed exploration of their pharmacodynamics and pharmacokinetics. Engaging with these topics not only enhances our comprehension of the underlying principles of chemistry but also inspires innovative approaches in the pursuit of medical advancements.
Solubility of (8R,9S,10R,13S,14S,17S)-17-hydroxy-13-methyl-2,6,7,8,9,10,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-one
The solubility of the compound (8R,9S,10R,13S,14S,17S)-17-hydroxy-13-methyl-2,6,7,8,9,10,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-one in various solvents can be influenced by several factors, including molecular structure and the presence of functional groups. Here are some key points regarding its solubility characteristics:
In conclusion, while the compound may have good solubility in organic solvents, its hydrophilic interactions remain weak in aqueous environments. Understanding these solubility traits is crucial for applications in pharmaceuticals, where solvent choice can significantly affect drug formulation.