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Estrone sulfate

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Identification
Molecular formula
C18H22O5S
CAS number
438-67-5
IUPAC name
[(8R,9S,13S)-13-methyl-17-oxo-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-3-yl] hydrogen sulfate
State
State

At room temperature, estrone sulfate is typically in a solid state. It is used primarily in research and therapeutic applications as a precursor in the biosynthesis of estrogens.

Melting point (Celsius)
243.00
Melting point (Kelvin)
516.15
Boiling point (Celsius)
740.80
Boiling point (Kelvin)
1 013.95
General information
Molecular weight
350.47g/mol
Molar mass
350.4660g/mol
Density
1.3400g/cm3
Appearence

Estrone sulfate appears as a white to off-white crystalline powder. It is practically odorless and is generally found as a component of estrogens used for therapeutic purposes.

Interesting facts

Interesting Facts about [(8R,9S,13S)-13-methyl-17-oxo-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-3-yl] Hydrogen Sulfate

This compound, often referred to in scientific literature, showcases the fascinating interplay between complex organic structures and functional groups. Here are some intriguing insights about this chemical:

  • Steroid Backbone: The structure of this compound indicates a steroid-like framework, typical of many biologically active substances. Steroids are integral in various physiological processes and often serve as hormones.
  • Functional Group Importance: The presence of the hydrogen sulfate group often influences the reactivity and solubility of a compound, making it a candidate for various chemical reactions, including esterification and nucleophilic substitutions.
  • Potential Biological Activity: Many compounds with similar sterol structures have exhibited pharmacological properties, suggesting that this compound may also have interesting therapeutic potentials worth exploring.
  • Origination and Synthesis: The synthesis of compounds like this can often involve complex organic reactions. Understanding the methodologies used to create such compounds can deepen our appreciation for the art of organic chemistry.
  • Chirality and Stereochemistry: With noted chiral centers in its structure, studying this compound affords a fascinating look into stereochemistry and how the spatial arrangement of atoms affects the properties and behavior of molecules.

As articulated by some prominent chemists, "The beauty of organic compounds lies within their complexity and the diversity of their transformations." This compound is a prime example of that beauty, inviting both students and seasoned scientists into the engaging world of organic chemistry.

Such compounds not only deepen our understanding of chemical interactions but also pave the way for innovations in fields ranging from pharmaceuticals to materials science.