Skip to main content

Ethinylestradiol

ADVERTISEMENT
Identification
Molecular formula
C20H24O2
CAS number
57-63-6
IUPAC name
(8R,9S,13S,14S,17R)-17-ethynyl-3-methoxy-13-methyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-ol;hydrogen carbonate
State
State

At room temperature, ethinylestradiol is found in a solid state, generally as a powder.

Melting point (Celsius)
182.00
Melting point (Kelvin)
455.15
Boiling point (Celsius)
370.00
Boiling point (Kelvin)
643.15
General information
Molecular weight
296.40g/mol
Molar mass
296.4030g/mol
Density
1.2800g/cm3
Appearence

Ethinylestradiol is typically a white to creamy white, odourless, crystalline powder. It is sensitive to light and should be stored in a well-closed container at room temperature, protected from light.

Comment on solubility

Solubility of (8R,9S,13S,14S,17R)-17-ethynyl-3-methoxy-13-methyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-ol; hydrogen carbonate

The solubility of the compound (8R,9S,13S,14S,17R)-17-ethynyl-3-methoxy-13-methyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-ol in hydrogen carbonate can be influenced by several factors, making it interesting to analyze:

  • Polarity: The presence of polar functional groups, such as the methoxy group in this compound, suggests potential solubility in polar solvents.
  • Hydrogen Bonding: The -OH group might engage in hydrogen bonding, enhancing its solubility in solvents like water compared to non-polar solvents.
  • Hydrophobic Regions: The numerous aliphatic and aromatic structures contribute to hydrophobic characteristics, which might limit its solubility in highly polar solvents.

In general, the solubility of this compound can be summarized as follows:

  1. **Good solubility** in polar, protic solvents (e.g., alcohols).
  2. **Limited solubility** in apolar solvents (e.g., hexane).
  3. **Variable** solubility in mixed solvents, depending on the proportion of polar and non-polar components.

As a result, it is crucial to consider the solvent's nature when attempting to dissolve this compound, as "like dissolves like" is a fundamental principle in solubility.

Interesting facts

Interesting Facts About (8R,9S,13S,14S,17R)-17-ethynyl-3-methoxy-13-methyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-ol; hydrogen carbonate

This compound, often referred to in biochemical studies, has garnered attention due to its unique structural characteristics and potential applications. Here are some noteworthy points:

  • Steroidal Framework: The compound possesses a cyclopenta[a]phenanthrene backbone, which is a type of steroid structure. This lends to its biological activity and makes it a subject of interest in pharmacology.
  • Ethynyl Group: The presence of the ethynyl group (–C≡C–) contributes to the compound's chemical reactivity and can enhance its ability to interact with biological systems. Organisms often metabolize such groups, making it pertinent for studies in drug design.
  • Significance in Hormonal Studies: Compounds with similar structures are often explored for their roles in hormone regulation and signaling, particularly estrogenic activity. This makes the compound significant in understanding various physiological processes.
  • Functional Groups: The compound contains a methoxy (-OCH3) group, which has an electronegative oxygen atom that influences its reactivity and solubility. Methoxy groups are also known to affect the compound's biological activity.
  • Applications in Research: Owing to its complex structure, this compound is often utilized in advanced synthetic methodologies and medicinal chemistry research. The structural intricacies may lead to discoveries of novel therapeutic agents.

In conclusion, the exploration of this compound provides a promising endeavor for scientists seeking new insights into the mechanisms of action of complex molecules within biological systems. As research continues, we may uncover even more remarkable properties of (8R,9S,13S,14S,17R)-17-ethynyl-3-methoxy-13-methyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-ol; hydrogen carbonate.