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Testosterone undecanoate

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Identification
Molecular formula
C30H48O3
CAS number
5949-44-0
IUPAC name
[(8R,9S,13S,14S,17S)-3-hydroxy-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-17-yl] undecanoate
State
State

At room temperature, testosterone undecanoate is in a solid crystalline form.

Melting point (Celsius)
60.00
Melting point (Kelvin)
333.20
Boiling point (Celsius)
311.60
Boiling point (Kelvin)
584.80
General information
Molecular weight
456.71g/mol
Molar mass
456.7050g/mol
Density
1.0385g/cm3
Appearence

Testosterone undecanoate appears as a white or sometimes off-white crystalline powder. It is odorless and tasteless, providing ease of use in formulations typically used for medical and therapeutic purposes.

Comment on solubility

Solubility of [(8R,9S,13S,14S,17S)-3-hydroxy-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-17-yl] undecanoate

The solubility of the compound [(8R,9S,13S,14S,17S)-3-hydroxy-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-17-yl] undecanoate is influenced by several key factors, primarily its molecular structure and functional groups. This compound, with its complex steroid-like backbone, exhibits specific solubility properties that can generally be summarized as follows:

  • Polarity: The presence of the hydroxyl (-OH) group contributes to polar characteristics, enhancing solubility in polar solvents like water, albeit limited.

  • Hydrophobic regions: The extensive hydrocarbon tail (undecanoate moiety) facilitates solubility in nonpolar solvents such as hexane or chloroform.

  • Temperature effects: As with many organic compounds, increased temperature can improve solubility by disrupting intermolecular forces.

In general, the compound is expected to exhibit higher solubility in organic solvents than in aqueous solutions due to these attributes. This leads to a solubility profile that can be classified as moderate in polar solvents while being highly soluble in nonpolar solvents. Understanding this solubility behavior is crucial for applications ranging from pharmaceutical formulations to chemical synthesis.

Interesting facts

Interesting Facts about the Compound

The compound with the complex name [(8R,9S,13S,14S,17S)-3-hydroxy-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-17-yl] undecanoate possesses a remarkable structure and is of significant interest in various scientific fields.

Structural Features

This compound is a steroid derivative characterized by a polycyclic framework. It features:

  • Hydroxyl Groups: The presence of a hydroxyl group contributes to its biological activity and solubility properties.
  • Decalin Structure: The decahydrocyclopenta[a]phenanthrene unit gives it a unique three-dimensional shape which can influence its interactions with biological targets.

Biological Relevance

This compound is related to steroids that are critical in biological functions such as

  • Hormone Activity: Compounds of this nature may play roles in influencing various hormonal pathways.
  • Pharmaceutical Applications: Understanding its activity can lead to developments in therapies for conditions linked to steroid hormones.

Potential Uses

Given its structural attributes, the compound may have potential applications in:

  • Drug Design: It could serve as a lead compound in the synthesis of new pharmaceuticals.
  • Research: Essential for studying the mechanisms of steroid action and related diseases.

Chemical Synthesis

The synthesis of such complex molecules poses challenges and opportunities for chemical scientists. Key aspects include:

  • Chirality: The specific stereochemistry must be carefully controlled to ensure the desired biological activity.
  • Multistep Synthesis: Typically involves multiple reactions, requiring strategies for efficiency and yield.

In conclusion, studying this compound offers valuable insights into the world of steroid chemistry and its critical roles in health and disease. As scientists and students continue to explore its potential, we can expect to uncover more about its intriguing properties and applications.

Synonyms
ESTRADIOL UNDECYLATE
3571-53-7
Delestrec
Estradiol 17-undecanoate
Depogin
Primogyn Depot
Estradiol undecylate [INN]
Oestradioli undecylas
Estradiol 17-undecylate
SQ 9993
H3N3A8MFJC
Oestradiol-Retard Theramex
Delestrec (TN)
Estradiol undecylate [USAN:INN]
Estradioli undecylas [INN-Latin]
EINECS 222-677-3
Undecylate d'estradiol [INN-French]
Undecilato de estradiol [INN-Spanish]
SQ-9993
AI3-52642
DTXSID3023003
Estra-1,3,5(10)-triene-3,17-diol (17beta)-, 17-undecanoate
ESTRADIOL UNDECYLATE [USAN]
ESTRADIOL UNDECYLATE [WHO-DD]
Estra-1,3,5(10)-triene-3,17-diol (17.beta.)-, 17-undecanoate
Estradioli undecylas (INN-Latin)
Undecylate d'estradiol (INN-French)
Undecilato de estradiol (INN-Spanish)
DTXCID503003
222-677-3
Undecylate d'estradiol
Undecilato de estradiol
[(8R,9S,13S,14S,17S)-3-hydroxy-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-17-yl] undecanoate
Estradioli undecylas
Estradiolo undecilato
UNII-H3N3A8MFJC
Estradiolo undecilato [DCIT]
SCHEMBL453172
CHEMBL1697794
CHEBI:135719
Estradiol undecylate (USAN/INN)
TXHUMRBWIWWBGW-GVGNIZHQSA-N
(17beta)-3-hydroxyestra-1(10),2,4-trien-17-yl undecanoate
BCP09821
AKOS040751723
NS00029904
D04065
Q5401764
AI3-52642; AI3 52642; AI352642