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Testosterone cypionate

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Identification
Molecular formula
C27H40O3
CAS number
58-20-8
IUPAC name
[(8R,9S,13S,14S,17S)-3-hydroxy-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-17-yl] 3-cyclopentylpropanoate
State
State

At room temperature, testosterone cypionate is typically in a crystalline solid state, which is then dissolved in a suitable oil for injection purposes.

Melting point (Celsius)
98.50
Melting point (Kelvin)
371.65
Boiling point (Celsius)
545.80
Boiling point (Kelvin)
818.95
General information
Molecular weight
412.61g/mol
Molar mass
412.6110g/mol
Density
1.0670g/cm3
Appearence

Testosterone cypionate typically appears as a white or creamy white crystalline powder. It is often provided as a solution for intramuscular injection in a base oil. The solution, when prepared, is usually clear and oily.

Comment on solubility

Solubility of [(8R,9S,13S,14S,17S)-3-hydroxy-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-17-yl] 3-cyclopentylpropanoate

The solubility characteristics of this intricate compound can be quite interesting yet challenging to summarize. Here's a closer look:

  • Polarity: The presence of hydroxyl groups generally increases solubility in polar solvents.
  • Hydrophobic Regions: The large cyclopentyl substituent suggests that the compound also possesses hydrophobic characteristics, potentially limiting its overall solubility in water.
  • Aromatic Systems: The fused ring system could introduce complex interactions with other organic solvents, enhancing solubility in non-polar media.
  • Temperature Effects: Increasing temperature often leads to increased solubility for many organic compounds, which could apply here.

It is essential to consider these factors together. While this compound may exhibit reasonable solubility in organic solvents such as ethanol or dimethyl sulfoxide (DMSO), one might encounter challenges in aqueous solutions. Quotes by researchers often remind us that:

“Solubility is not merely the property of a substance; it’s the key to understanding its potential applications.”

In summary, the solubility of this compound is dictated by a balance between its polar and non-polar functional groups, temperature, and the solvent type in question.

Interesting facts

Interesting Facts about [(8R,9S,13S,14S,17S)-3-hydroxy-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-17-yl] 3-cyclopentylpropanoate

This compound, with its complex structure, represents a fascinating intersection of organic chemistry and potential pharmaceutical applications. Its unique stereochemistry is denoted by the detailed R/S configuration, indicating that the spatial arrangement of atoms is crucial for its biological activity.

Key Features:

  • Biological Significance: Compounds with similar structures have been explored for their hormonal activities and therapeutic potential, especially as steroid analogs.
  • Structural Complexity: The layered cyclic structure showcases the intricate nature of organic molecules, often challenging for synthetic chemists to replicate.
  • Applications: It may have implications in fields such as pharmacology and biochemistry, where understanding the interaction of related compounds with biological systems is key.

One notable aspect of this compound is how it may influence various biochemical pathways, thanks to the hydroxyl group attached in its structure, which can facilitate interactions within biological systems. Additionally, the presence of a cyclopentyl group adds to the molecule's lipophilicity, potentially affecting its interaction with cellular membranes.

In summary, studying compounds like this not only enhances our understanding of molecular function but also provides insight into the development of new therapeutic agents. As we innovate in drug design, the detailed geometry and functionality of such compounds will continue to inspire scientific inquiry and discovery.

Synonyms
estradiol cypionate
313-06-4
Depofemin
Depoestradiol
Depo-Estradiol
Depoestra
Estradep
Estrapo
Estro-Depo
Dep-Estro
Femogen CYP
Depoestradiol cypionate
Estradiol 17-cypionate
beta-Estradiol 17-cypionate
depGynogen
Pertradiol
Estradiol cyclopentylpropionate
Estradiol (cypionate)
E. Ionate P.A.
Neoginon Depositum
Estradiol 17beta-cypionate
Estradiol 17-cyclopentylpropionate
Depo-estradiol cyclopentylpropionate
Estradiol cipionate
NSC 3354
Cyclopentanepropionic acid, 17-ester with estradiol
NSC-3354
EINECS 206-237-8
Estradiol, 17-cyclopentanepropionate
Estradiol 17beta-cylopentylpropionate
UNII-7E1DV054LO
Estradiol 17beta-cyclopentanepropionate
BRN 3171075
7E1DV054LO
DTXSID4022999
17beta-Estradiol 17-cyclopentylpropionate
NSC3354
MFCD00056558
Estradiol cypionate (USP)
Estradiol cypionate [USP]
17.beta.-Estradiol cypionate
Estradiol 17.beta.-cypionate
DTXCID302999
CHEBI:34745
4-09-00-00047 (Beilstein Handbook Reference)
Estradiol 17beta-cyclopentylpropionate
17.beta.-Estradiol cyclopentylpropionate
Estradiol 17.beta.-cyclopentylpropionate
17.beta.-Estradiol cyclopentanepropionate
Estradiol 17.beta.-cyclopentanepropanoate
Estradiol 17.beta.-cyclopentanepropionate
ESTRADIOL-17-CYCLOPENTANEPROPIONATE
LUNELLE COMPONENT ESTRADIOL CYPIONATE
17.beta.-Estradiol 17-cyclopentylpropionate
Cyclopentanepropionic acid, 3-hydroxyestra-1,3,5(10)-trien-17beta-yl ester
Estra-1,3,5(10)-triene-3,17-diol, (17beta)-, 17-cyclopentanepropanoate
DEPO-TESTADIOL COMPONENT ESTRADIOL CYPIONATE
ESTRADIOL CIPIONATE (MART.)
ESTRADIOL CIPIONATE [MART.]
ESTRADIOL CYPIONATE (USP-RS)
ESTRADIOL CYPIONATE [USP-RS]
ECP (VAN)
CAS-313-06-4
SMR000058700
ESTRADIOL CYPIONATE (USP MONOGRAPH)
ESTRADIOL CYPIONATE [USP MONOGRAPH]
Estradiol 17-cyclopentanepropionate
Depestro
Estra-1,3,5(10)-triene-3,17-diol (17.beta.)-, 17-cyclopentanepropanoate
estradiol-cypionate
NCGC00166134-01
Depo-estradiol (TN)
Estradiol Cypionate salt
ESTRADIOLI CYPIONAS
SCHEMBL41551
MLS000069763
MLS001074891
Estradiol cypionate (Standard)
CHEMBL1200973
HY-B1100R
HMS2234K11
ESTRADIOL CYPIONATE [VANDF]
BCP11930
HY-B1100
Tox21_110003
Tox21_112331
Tox21_301818
Estra-1,3,5(10)-triene-3,17beta-diol 17-(cyclopentanepropionate)
ESTRADIOL CIPIONATE [WHO-DD]
ESTRADIOLI CYPIONAS [WHO-IP]
s4046
|A-Estradiol 17-Cyclopentylpropionate
AKOS015895730
Estra-1,3,5(10)-triene-3,17-diol (17beta)-, 17-cyclopentanepropanoate
Tox21_112331_1
.BETA.-ESTRADIOL 17-CYPIONATE
beta-Estradiol 17-Cyclopentylpropionate
CCG-268613
CS-4691
DB13954
FE61563
KS-5296
Estradiol 17.beta.-cylopentylpropionate
|A- Estradiol-17-cyclopentyl propionate
ESTRADIOL CYPIONATE [ORANGE BOOK]
NCGC00013034-01
NCGC00166134-02
NCGC00166134-03
NCGC00255333-01
(1S,11S,14S,15S,10R)-5-hydroxy-15-methyltetracyclo[8.7.0.0<2,7>.0<11,15>]hepta deca-2,4,6-trien-14-yl 3-cyclopentylpropanoate
[(8R,9S,13S,14S,17S)-3-hydroxy-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-17-yl] 3-cyclopentylpropanoate
NCI60_002938
E0875
ESTRADIOL 17beta-CYCLOPENTANEPROPANOATE
NS00022039
D04063
ESTRADIOL CYPIONATE COMPONENT OF LUNELLE
EN300-19734590
Q5401760
ESTRADIOL 17.BETA.-CYCLOPENTANEPROPANOATE [MI]
ESTRADIOL CYPIONATE COMPONENT OF DEPO-TESTADIOL
1,3,5(10)-Estratriene-3,17beta-diol 17-cyclopentylpropionate
3,17beta-Hydroxy-1,3,5(10)-estratriene 17-cyclopentylpropionate
(17beta)-3-hydroxyestra-1(10),2,4-trien-17-yl 3-cyclopentylpropanoate
17.beta.-[(3-Cyclopentylpropanoyl)oxy]estra-1,3,5(10)-trien-3-ol
Estra-1,5(10)-triene-3,17-diol (17.beta.)-, 17-cyclopentanepropanoate
Estra-1,5(10)-triene-3,17-diol, (17.beta.)-, 17-cyclopentanepropanoate
Estradiol cypionate, United States Pharmacopeia (USP) Reference Standard
(17.beta.)-Estra-1,3,5(10)-triene-3,17-diol 17.beta.-cyclopentanepropanoate
Cyclopentanepropionic acid, 3-hydroxyestra-1,3,5(10)-trien-17.beta.-yl ester
Estra-1,3,5(10)-triene-3,17-diol, (17.beta.)-, 17-cyclopentanepropanoate
(1S,3aS,3bR,9bS,11aS)-7-hydroxy-11a-methyl-1H,2H,3H,3aH,3bH,4H,5H,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-1-yl 3-cyclopentylpropanoate
(8R,9S,13S,14S,17S)-3-hydroxy-13-methyl-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthren-17-yl 3-cyclopentylpropanoate
206-237-8