Testosterone heptanoate | Solubility of Things

Identification

Molecular formula

C₂₆H₄₀O₃

CAS number

315-37-7

IUPAC name

[(8R,9S,13S,14S,17S)-3-hydroxy-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-17-yl] heptanoate

State

At room temperature, testosterone heptanoate is in a solid state. It is most commonly used in the preparation of solutions or suspensions for intramuscular injection due to its role in hormone replacement therapies.

Melting point (Celsius)

47.00

Melting point (Kelvin)

320.15

Boiling point (Celsius)

440.00

Boiling point (Kelvin)

713.15

General information

Molecular weight

400.61g/mol

Molar mass

400.6030g/mol

Density

1.0500g/cm³

Appearence

Testosterone heptanoate typically appears as a white or cream-colored crystalline powder. It may also be found in a microcrystalline form, depending on its specific processing for pharmaceutical uses. Its crystalline nature can give it a somewhat glossy appearance under light.

Comment on solubility

Solubility of [(8R,9S,13S,14S,17S)-3-hydroxy-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-17-yl] heptanoate

The solubility of complex organic compounds like [(8R,9S,13S,14S,17S)-3-hydroxy-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-17-yl] heptanoate can be quite intriguing due to various factors influencing their behavior in different solvents. Generally, the solubility depends on:

Polarity: Organic compounds typically exhibit solubility in non-polar or slightly polar solvents. The presence of hydroxy groups, such as in this compound, may enhance some degree of solubility in polar solvents.
Hydrophobic vs. Hydrophilic Balance: The hydrophilic (water-attracting) groups compete with the hydrophobic (water-repelling) portions of the molecule. This compound's bulky structure suggests it may be more lipophilic, potentially rendering it less soluble in water.
Temperature: Solubility often increases with temperature for many organic compounds, which means that higher temperatures might improve the solubility of this compound in suitable solvents.
Concentration of the Solvent: The specific interactions of the solute with solvents are critical; the compound may have varying solubility in different concentrations of solvents.

In summary, the solubility of [(8R,9S,13S,14S,17S)-3-hydroxy-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-17-yl] heptanoate is influenced by its molecular structure, with considerations on polarity, temperature, and the specific interactions with solvent environments playing crucial roles. It is essential for researchers to conduct solubility tests for precise applications.

Interesting facts

Interesting Facts about Heptanoate Derivative

The compound [(8R,9S,13S,14S,17S)-3-hydroxy-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopentaphenanthren-17-yl] heptanoate is a fascinating addition to the realm of organic chemistry, particularly due to its complex structure and potential biological significance.

Key Features

Stereochemistry: This compound features multiple chiral centers, which contributes to its unique stereochemical properties. Understanding these configurations is crucial as they can significantly influence the biological activity and interaction of the compound with enzymes or receptors.
Hydroxyl Group: The presence of the hydroxyl (–OH) group suggests potential for hydrogen bonding, which may enhance its solubility in biological systems and affect its reactivity.
Cyclopenta[a]phenanthrene Framework: The structure boasts a multi-fused polycyclic ring system. This framework is often observed in steroidal compounds and may play a role in mimicking endogenous hormones.

Biological Implications

Compounds like this one have demonstrated significant importance in pharmacology. Here are some potential implications:

Drug Design: Due to its structural similarities to steroid hormones, this compound may serve as a valuable scaffold in drug development for conditions related to hormonal imbalances.
Research Models: Given its distinctive characteristics, it may also be used in medicinal chemistry as a model to study receptor interactions and molecular mechanisms.

Conclusion

In summary, the unique stereochemistry and functional groups of this heptanoate derivative make it a compound of interest not only for its chemical properties but also for its potential applications in the medical field. Researchers continue to explore the myriad ways that such compounds can influence health and disease, paving the way for novel therapeutic agents.

Estradiol 17-heptanoate

Estradiol enanthate [USAN]