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Testosterone pentanoate

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Identification
Molecular formula
C24H36O3
CAS number
315-37-7
IUPAC name
[(8R,9S,13S,14S,17S)-3-hydroxy-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-17-yl] pentanoate
State
State

At room temperature, testosterone pentanoate is generally in a solid crystalline state. It may appear as a fine powder and can sometimes form larger crystals depending on its purity and preparation method.

Melting point (Celsius)
48.00
Melting point (Kelvin)
321.15
Boiling point (Celsius)
460.97
Boiling point (Kelvin)
734.12
General information
Molecular weight
386.57g/mol
Molar mass
386.5670g/mol
Density
1.0600g/cm3
Appearence

Testosterone pentanoate is typically found as a white or almost white crystalline powder. It may appear somewhat oily upon closer inspection due to the ester functional group attached to the testosterone core structure.

Comment on solubility

Solubility of the Compound

The solubility of the compound [(8R,9S,13S,14S,17S)-3-hydroxy-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-17-yl] pentanoate can be assessed with consideration to various factors:

  • Hydrophilicity vs. Hydrophobicity: The presence of the hydroxyl (-OH) group may impart some hydrophilic characteristics. However, the large hydrophobic hydrocarbon backbone likely dominates, suggesting low water solubility.
  • Solvents: This compound may show greater solubility in organic solvents such as ethanol, chloroform, or dimethyl sulfoxide (DMSO), rather than in polar solvents like water.
  • Temperature Effects: Solubility can also be temperature-dependent; higher temperatures may enhance solubility in organic solvents.
  • Potential Applications: Poor water solubility can limit bioavailability in pharmacological contexts, making formulation strategies critical.

In summary, the solubility profile of this compound is expected to be low in aqueous environments due to its structural characteristics. It is always recommended to conduct empirical solubility tests for accurate data.

Interesting facts

Interesting Facts about [(8R,9S,13S,14S,17S)-3-hydroxy-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-17-yl] pentanoate

This compound is part of a fascinating class of molecules that play a crucial role in various biological processes and medicinal applications. Often known for its structural complexity, it presents a unique combination of features that make it of interest to chemists and biologists alike.

Key Characteristics

  • Structural Diversity: Its intricate multi-ring structure provides a range of reactive sites, making it a target for synthesis and modification in medicinal chemistry.
  • Biological Significance: Compounds like these are often involved in hormonal activity and can exhibit anabolic properties, influencing muscle growth and development.
  • Natural Variants: This particular compound can be found in various natural sources, where it may contribute to physiological functions.

Understanding compounds like this one can offer insight into:

  • Drug Development: Studying similar structures aids in the design of new pharmaceuticals and understanding their potential therapeutic effects.
  • Endocrinology: Their interaction with hormonal pathways makes them vital in researching hormonal therapies and disorders.

As noted by some researchers, "the complexity and the biological relevance of such structures can yield significant insights into both organic synthesis and pharmacology." The exploration of this compound and its relatives showcases the continuous interplay between structure and function in chemistry, inviting ongoing study and discovery.

Synonyms
estradiol valerate
979-32-8
Estradiol 17-valerate
Estradiol valerianate
Estraval
Neofollin
Femogex
Oestradiol valerate
Atladiol
Climaval
Deladiol
Duratrad
Estate
Dura-estradiol
Exten strone
Depo estro med
Repo-Estra
Delestrogen 4X
Estraval PA
Estraval 2X
Estroval-10
Pelanin
Depo-Estro-Med
Cyclocur
Femogen-L.A.
Gynokadin
Merimono
Postoval
Primogyna
Nuvelle
Ronfase
Estradiol Depot
Primogyn-Depot
ESTRADIOL, 17-VALERATE
Estradiol 17beta-valerate
beta-Estradiol 17-valerate
NSC-17590
CCRIS 5571
EINECS 213-559-2
NSC 17590
UNII-OKG364O896
Estradioli valeras [INN-Latin]
DTXSID8023004
OKG364O896
Valerate d'estradiol [INN-French]
Valerato de estradiol [INN-Spanish]
3-Hydroxy-17beta-valeroyloxyestra-1,3,5(10)-triene
DTXCID903004
NSC17590
Estradiol valerate [USP:INN:BAN:JAN]
Estra-1,3,5(10)-triene-3,17-diol(17beta)-, 17-pentanoate
Estra-1,3,5(10)-triene-3,17-diol (17-beta)-, 17-pentanoate
DITATE-DS COMPONENT ESTRADIOL VALERATE
Estradioli valeras (INN-Latin)
ESTRADIOL VALERATE (MART.)
ESTRADIOL VALERATE [MART.]
Valerate d'estradiol (INN-French)
ESTRADIOL VALERATE (USP-RS)
ESTRADIOL VALERATE [USP-RS]
Valerato de estradiol (INN-Spanish)
Estradiol valerate (USP:INN:BAN:JAN)
ESTRADIOL VALERATE (EP MONOGRAPH)
ESTRADIOL VALERATE [EP MONOGRAPH]
estradiol valeriante
ESTRADIOL VALERATE (USP MONOGRAPH)
ESTRADIOL VALERATE [USP MONOGRAPH]
ESTRADIOL VALERATE COMPONENT OF DITATE-DS
Estra-1,3,5(10)-triene-3,17beta-diol 17-petanoate
213-559-2
Delestrogen
Progynova
Progynon-Depot
Altadiol
Gynogen L.A. 20
Gynogen L.A. 40
Valerate d'estradiol
Valerato de estradiol
Deladumone
component of Ditate
17-BETA-ESTRADIOL 17-VALERATE
3-Hydroxy-17beta-valeroyloxyestra-1,3,5(10)-trien
B-Estradiol 17-valerate
MFCD00056541
component of Deluteval 2X
Estradiol 17.beta.-valerate
component of Mal-O-Fem L.A
Estradiol valerate (Standard)
.beta.-estradiol 17-valerate
MLS000028449
CHEBI:31561
[(8R,9S,13S,14S,17S)-3-hydroxy-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-17-yl] pentanoate
SMR000058346
17-pentanoyl-estra-1,3,5(10)-triene-3,17beta-diol
Gynogen L.A. 10
(17beta)-3-hydroxyestra-1,3,5(10)-trien-17-yl valerate
Valergen
Estradiol valerate (VAN)
Estradioli valeras
Oestradiol-17b-valerate
Pelanin depot
estradiol-valerate
Gynogen LA
Deladumone (TN)
NCGC00094673-01
Gynogen L.A.10
ST075188
Estradiol valerate ICRS
Opera_ID_444
-Estradiol 17-valerate
1,3,5(10)-Estratriene-3,17beta-diol 17-pentanote
17-alpha-Estradiol valerate
CHEMBL1511
SCHEMBL40563
MLS001146931
GTPL7655
ESTRADIOL VALERATE [INN]
ESTRADIOL VALERATE [JAN]
HY-B0672R
ESTRADIOL VALERATE [VANDF]
HMS2232L17
HMS3259C12
HMS3715B21
(8R,9S,13S,14S,17S)-3-hydroxy-13-methyl-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthren-17-yl pentanoate
[(13S,17S)-3-hydroxy-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-17-yl] pentanoate
BCP11918
Estradiol valerate (JAN/USP/INN)
ESTRADIOL VALERATE [WHO-DD]
HY-B0672
ESTRADIOL 17-VALERATE [MI]
Tox21_111312
Estra-1,3,5(10)-triene-3,17-diol (17.beta.)-, 17-pentanoate
LMST02010039
s3149
AKOS005267158
Estradiol-17-valerate; 1,3,5(10)-Estratriene-3,17b-diol 17-pentanote
CCG-221130
DB13956
ESTRADIOL VALERATE [GREEN BOOK]
FD12049
FE22827
KS-5213
NC00560
ESTRADIOL VALERATE [ORANGE BOOK]
Estradiol valerate for system suitability
NCGC00018166-02
NCGC00018166-14
(1S,11S,14S,15S,10R)-5-hydroxy-15-methyltetracyclo[8.7.0.0<2,7>.0<11,15>]hepta deca-2,4,6-trien-14-yl pentanoate
CAS-979-32-8
CPD000058346
CS-0694761
E0876
D01413
AB00382980_15
EN300-23841039
SR-01000003061
3-Hydroxy-17|A-valeroyloxyestra-1,3,5(10)-trien
Q5401768
SR-01000003061-3
BRD-K66766661-001-19-2
(17.beta.)-Estra-1,3,5(10)-triene-3,17-diol 17-valerate
(17beta)-3-hydroxyestra-1(10),2,4-trien-17-yl pentanoate
Estra-1,5(10)-triene-3,17-diol (17.beta.)-, 17-pentanoate
ESTRA-1,3,5(10)-TRIENE-3,17-DIOL(17.BETA.)-, 17-PENTANOATE
(17?)-Estra-1,3,5(10)-triene-3,17-diol 17-pentanoate;Estradiol valerate
(1S,3aS,3bR,9bS,11aS)-7-hydroxy-11a-methyl-1H,2H,3H,3aH,3bH,4H,5H,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-1-yl pentanoate