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Estradiol

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Identification
Molecular formula
C18H24O2
CAS number
50-28-2
IUPAC name
(8S,17S)-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthrene-3,17-diol
State
State

At room temperature, estradiol is a solid compound.

Melting point (Celsius)
173.00
Melting point (Kelvin)
446.00
Boiling point (Celsius)
445.80
Boiling point (Kelvin)
718.80
General information
Molecular weight
272.38g/mol
Molar mass
272.3820g/mol
Density
1.1699g/cm3
Appearence

Estradiol appears as a white to almost white crystalline powder.

Comment on solubility

Solubility of (8S,17S)-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthrene-3,17-diol

The solubility of (8S,17S)-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthrene-3,17-diol is an intriguing topic due to its unique structure and functionality. Here are some key aspects to consider:

  • Polarity: The presence of hydroxyl groups (-OH) in its structure suggests that the compound may exhibit some degree of polarity. This polarity can influence its solubility in various solvents.
  • Solvent Compatibility: It is likely to be more soluble in polar solvents such as methanol and ethanol, while showing limited solubility in nonpolar solvents like hexane.
  • Hydrogen Bonding: The hydroxyl groups may engage in hydrogen bonding, enhancing solubility in water but complicating solubility in nonpolar environments.
  • Temperature Dependency: Generally, solubility can also be influenced by temperature, with increased temperatures often leading to higher solubility for many organic compounds.

In summary, while the specific solubility characteristics of (8S,17S)-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthrene-3,17-diol are less defined in the literature, its structure suggests a tendency towards higher solubility in polar environments. Understanding these solubility dynamics is crucial for various applications, including pharmaceuticals and chemical synthesis.

Interesting facts

Interesting Facts about (8S,17S)-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthrene-3,17-diol

(8S,17S)-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthrene-3,17-diol is a fascinating compound primarily recognized for its structural complexity and potential biological activities. Here are some intriguing aspects:

  • Stereochemistry: This compound exhibits specific stereochemical configurations, notably at the 8th and 17th carbon positions, denoting its potential for interacting with biological systems in a highly selective manner.
  • Bioactive Properties: Compounds with similar structures often show a range of biological activities, including hormonal and anti-inflammatory effects, making them of great interest in pharmaceutical research.
  • Natural Occurrence: Many polycyclic compounds like this one can be derived from natural sources, including plants and marine organisms, which could suggest ecological significance and avenues for drug discovery.
  • Research Applications: The complexity of its structure makes it a good candidate for synthetic organic chemistry research, allowing scientists to explore synthesis techniques and new reaction mechanisms.

As the field of chemistry continues to evolve, compounds like (8S,17S)-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthrene-3,17-diol remind us of the intricate tapestry of molecules that underpin life and health. Understanding such compounds may unlock future innovations in drug development or material sciences.

Synonyms
DTXSID00965968
Estra-1(10),2,4-triene-3,17-diol