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Fluocinolone acetonide

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Identification
Molecular formula
C24H30F2O6
CAS number
67-73-2
IUPAC name
(8S,9R,10S,11S,13S)-9-fluoro-11-hydroxy-10,13-dimethyl-1,2,6,7,8,11,12,14,15,16-decahydrocyclopenta[a]phenanthrene-3,17-dione
State
State

At room temperature, this compound is in a solid state.

Melting point (Celsius)
272.00
Melting point (Kelvin)
545.15
Boiling point (Celsius)
500.00
Boiling point (Kelvin)
773.15
General information
Molecular weight
452.50g/mol
Molar mass
452.4980g/mol
Density
1.3000g/cm3
Appearence

This compound appears as a white to creamy white crystalline powder.

Comment on solubility

Solubility of (8S,9R,10S,11S,13S)-9-fluoro-11-hydroxy-10,13-dimethyl-1,2,6,7,8,11,12,14,15,16-decahydrocyclopenta[a]phenanthrene-3,17-dione

The solubility of this complex compound is a critical factor that influences its chemical behavior and potential applications. Understanding solubility can help predict its interaction with solvents as well as its overall stability. Here are some key points regarding the solubility of this compound:

  • Solvent Type: The solubility of organic compounds often depends on the polarity of the solvent. This compound, with its multiple functional groups, is likely to exhibit varied solubility in polar versus non-polar solvents.
  • Temperature Influence: Generally, increasing temperature can enhance solubility. It’s important to consider how temperature changes might affect this specific compound’s solubility.
  • pH Sensitivity: Compounds with acidic or basic functional groups may change solubility with pH variations. Evaluating the pH stability of the functional groups in this compound is essential.
  • Structural Characteristics: The presence of hydroxyl and fluorine groups may contribute to solubility in polar solvents. As a result, one might expect this compound to be more soluble in water than in hydrocarbons.

As we explore further, it's essential to conduct systematic solubility tests under different conditions to fully understand the solubility dynamics of this intriguing compound. Conducting experiments will provide both qualitative and quantitative insights, paving the way for more effective utilization in various applications.

Interesting facts

Interesting Facts about (8S,9R,10S,11S,13S)-9-fluoro-11-hydroxy-10,13-dimethyl-1,2,6,7,8,11,12,14,15,16-decahydrocyclopenta[a]phenanthrene-3,17-dione

This compound is a unique member of the class known as tricyclic compounds, characterized by its complex polycyclic structure. Here are some fascinating insights into this fascinating chemical:

  • Stereochemistry: The designation of stereocenters in its name (8S, 9R, 10S, 11S, 13S) indicates that this compound exhibits chiral properties. Stereochemistry plays a crucial role in determining the biological activity of compounds, often influencing how drugs interact with biological systems.
  • Biological Importance: Compounds similar to this one have been studied extensively for their potential therapeutic applications, particularly in the field of pharmacology. The presence of the hydroxy and fluoro groups can significantly affect the compound's reactivity and bioactivity, which may lead to various medicinal benefits.
  • Structural Complexity: Its highly intricate structure brings challenges for synthesis and characterization in the laboratory. The need for advanced synthetic techniques makes studying such compounds exhilarating, offering students and researchers hands-on experience in solving complex chemical problems.
  • Applications in Research: This compound may pave the way for exploring new realms in medicinal chemistry. Due to the unique features of its structure, it can serve as a scaffold for designing new drugs that can target specific biological pathways.

In summary, the study of (8S,9R,10S,11S,13S)-9-fluoro-11-hydroxy-10,13-dimethyl-1,2,6,7,8,11,12,14,15,16-decahydrocyclopenta[a]phenanthrene-3,17-dione not only highlights essential concepts in stereochemistry and structural complexity but also opens avenues for significant scientific inquiries in therapeutics and materials science.

Synonyms
9-fluoro-11-hydroxyandrost-4-ene-3,17-dione
(8S,9R,10S,11S,13S)-9-fluoro-11-hydroxy-10,13-dimethyl-1,2,6,7,8,11,12,14,15,16-decahydrocyclopenta[a]phenanthrene-3,17-dione
DTXSID30957098