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9-(2-Chloroethyl)carbazole

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Identification
Molecular formula
C14H12ClN
CAS number
33327-35-4
IUPAC name
9-(2-chloroethyl)carbazole
State
State

At room temperature, 9-(2-Chloroethyl)carbazole is in a solid state. The stability of the compound as a solid makes it suitable for storage and handling under standard laboratory conditions. It should be kept in a dry and cool environment to maintain its integrity.

Melting point (Celsius)
70.00
Melting point (Kelvin)
343.15
Boiling point (Celsius)
374.00
Boiling point (Kelvin)
647.15
General information
Molecular weight
227.71g/mol
Molar mass
227.7120g/mol
Density
1.2390g/cm3
Appearence

9-(2-Chloroethyl)carbazole is typically a pale yellow to off-white crystalline solid. It may also be encountered as a powder. The compound's appearance can change slightly depending on its purity and the presence of any impurities or solvents.

Comment on solubility

Solubility of 9-(2-chloroethyl)carbazole

9-(2-chloroethyl)carbazole exhibits unique solubility behavior due to its structural characteristics. Its solubility can be influenced by several factors, making it pertinent for various applications:

  • Solvent Dependence: This compound is generally soluble in organic solvents, such as ethanol, methanol, and acetone. However, it has limited solubility in polar solvents like water.
  • Temperature Effects: The solubility of 9-(2-chloroethyl)carbazole may increase with temperature, which is a common behavior among many organic compounds.
  • Crystallization: Its crystalline nature can lead to lower solubility in some cases, which can complicate processes where high solubility is desired.

In summary, when considering the solubility of 9-(2-chloroethyl)carbazole, one should prioritize organic solvents and take into account temperature variations that can affect its dissolution characteristics. The potential limits in aqueous solubility are a critical factor when integrating this compound into various chemical processes.

Interesting facts

Interesting Facts about 9-(2-Chloroethyl)carbazole

9-(2-Chloroethyl)carbazole is an intriguing compound with a variety of potential applications, particularly in the field of medicinal chemistry and material science. Here are some fascinating insights:

  • Pharmaceutical Applications: This compound is often explored for its anticancer properties. The chloroethyl group is known to participate in alkylation reactions, which are pivotal in the development of certain chemotherapeutic agents.
  • Structural Importance: The carbazole backbone itself is significant in the realm of organic electronics, showing promise in the development of OLEDs (Organic Light Emitting Diodes) and solar cells.
  • Reactivity: The presence of the chloroethyl substituent renders the compound reactive, allowing it to interact with biological macromolecules such as DNA, which could lead to further exploration in cancer drug development.
  • Toxicology Studies: As with many compounds that exhibit biological activity, understanding the toxicity profile of 9-(2-chloroethyl)carbazole is crucial. Studies can provide insight into both therapeutic potential and safety concerns.

As a scientist studying this compound, one can appreciate how structure dictates function. The strategic incorporation of halogen atoms in organic molecules opens a doorway to numerous synthetic pathways. Therefore, understanding compounds like 9-(2-chloroethyl)carbazole is vital for both academic research and practical applications in drug development and advanced materials.

In the words of a famous chemist, "Chemistry is not about atoms. It’s about the interactions between atoms." This compound exemplifies that notion, highlighting the delicate balance between chemical structure and biological impact.

Synonyms
9-(2-Chloroethyl)carbazole
1140-35-8
USAF uctl-188
9-(2-chloroethyl)-9H-carbazole
N-(2-Chloroethyl)carbazole
CARBAZOLE, 9-(2-CHLOROETHYL)-
9H-Carbazole, 9-(2-chloroethyl)-
N-(beta-Chloroethyl)carbazole
9-(beta-Chloroethyl)carbazole
NSC 39039
BRN 0165176
NSC39039
5-20-08-00017 (Beilstein Handbook Reference)
SCHEMBL1478604
DTXSID2074459
9-(.beta.-Chloroethyl)carbazole
NSC-39039
STK927743
AKOS002242683
9-(2-CHLORO-ETHYL)-9H-CARBAZOLE
AH-034/32471036