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Tadalafil

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Identification
Molecular formula
C22H19N3O4
CAS number
171596-29-5
IUPAC name
9-[2-(diethylamino)ethyl]-2-methyl-3,4-dihydro-2H-carbazol-1-one
State
State

At room temperature, Tadalafil is in a solid state.

Melting point (Celsius)
301.60
Melting point (Kelvin)
574.80
Boiling point (Celsius)
744.50
Boiling point (Kelvin)
1 017.70
General information
Molecular weight
389.40g/mol
Molar mass
389.4040g/mol
Density
1.5123g/cm3
Appearence

Tadalafil is typically a white to off-white crystalline powder.

Comment on solubility

Solubility of 9-[2-(diethylamino)ethyl]-2-methyl-3,4-dihydro-2H-carbazol-1-one

The solubility of 9-[2-(diethylamino)ethyl]-2-methyl-3,4-dihydro-2H-carbazol-1-one can be quite intriguing due to its unique structure and the presence of functional groups. Understanding its solubility profile is essential for applications in various fields, such as pharmaceuticals and materials science. Here are some key points regarding its solubility:

  • Solvent Compatibility: The compound is likely to exhibit greater solubility in organic solvents like ethanol, dimethyl sulfoxide (DMSO), and chloroform due to the hydrophobic carbazole moiety and the electron-donating properties of the diethylamino group.
  • Aqueous Solubility: Aqueous solubility may be limited because of its relatively large and non-polar structure, leading to a decreased affinity for polar solvents such as water.
  • Influence of Temperature: Increased temperature generally enhances solubility for many organic compounds; hence, this compound may dissolve more readily at elevated temperatures.
  • Role of pH: The solubility may also be affected by pH levels, especially if any ionizable groups are present, which can influence ionization and subsequent solubility.

Overall, the solubility of 9-[2-(diethylamino)ethyl]-2-methyl-3,4-dihydro-2H-carbazol-1-one can be summarized as being moderately soluble in organic solvents, with potential limitations in polar environments. Understanding these factors is crucial for harnessing its properties effectively.

Interesting facts

Interesting Facts about 9-[2-(Diethylamino)ethyl]-2-methyl-3,4-dihydro-2H-carbazol-1-one

This intriguing compound, commonly known as a derivative of carbazole, belongs to a class of organic molecules known for their unique structural features and biological properties. Let's delve into what makes this compound particularly noteworthy:

  • Biological Role: Compounds similar to this have been widely studied for their potential pharmacological properties, including antidepressant and anticancer activities, drawing interest in medical and pharmaceutical research.
  • Unique Structure: The structure houses a diethylamino group, which enhances its solubility and bioactivity, allowing it to interact effectively in biological systems. This modification often leads to improved pharmacokinetic properties compared to simpler structures.
  • Fluorescent Properties: Certain carbazole derivatives exhibit fluorescence, making them valuable in materials science—for example, in organic light-emitting diodes (OLEDs) and as fluorescent probes in bioconjugation and imaging studies.
  • Environmental Impact: Carbazole and its derivatives are of interest in the study of environmental chemistry because they can be found as products of combustion and may have implications in pollution. Understanding their behavior in the environment is critical for assessing their ecological impact.
  • Self-Assembly: Some derivatives are known to participate in self-assembly processes, forming unique supramolecular structures. This property opens avenues for developing new materials with tailored functionalities.

In conclusion, the compound 9-[2-(diethylamino)ethyl]-2-methyl-3,4-dihydro-2H-carbazol-1-one exemplifies the intricate connections between chemical structure and biological function. Whether in pharmaceuticals or material sciences, the study of such compounds continues to reveal their profound relevance and applicability.