Skip to main content

Carbamazepine

ADVERTISEMENT
Identification
Molecular formula
C15H13NO
CAS number
298-46-4
IUPAC name
9-[2-(diethylamino)ethyl]-3,4-dihydro-2H-carbazol-1-one
State
State

Carbamazepine is primarily in a solid crystalline state at room temperature. It is utilized in a myriad of pharmaceutical formulations, particularly in its solid form.

Melting point (Celsius)
190.00
Melting point (Kelvin)
463.15
Boiling point (Celsius)
360.00
Boiling point (Kelvin)
633.15
General information
Molecular weight
236.29g/mol
Molar mass
191.2580g/mol
Density
1.1603g/cm3
Appearence

Carbamazepine appears as a white to off-white crystalline powder. It is tasteless and has a slightly bitter taste. The compound has a characteristic odor associated with its class of pharmaceuticals.

Comment on solubility

Solubility of 9-[2-(diethylamino)ethyl]-3,4-dihydro-2H-carbazol-1-one

The solubility of 9-[2-(diethylamino)ethyl]-3,4-dihydro-2H-carbazol-1-one can vary based on several factors, including temperature and the solvent used. Generally, this compound is expected to have moderate solubility in organic solvents, which may include:

  • Dimethyl sulfoxide (DMSO)
  • Methanol
  • Chloroform

However, it tends to be poorly soluble in polar solvents like water due to its relatively large and hydrophobic aromatic structure. This characteristic is often attributed to:

  1. The presence of bulky diethylamino groups, which increase steric hindrance.
  2. The hydrophobic nature of the carbazole ring, which is generally insoluble in water.

In practical applications, when working with this compound, it is crucial to consider these solubility limitations, as they can significantly affect its performance and behavior in various chemical reactions or formulations. It's always recommended to conduct solubility tests under controlled conditions to determine the most effective solvent for specific applications.

Interesting facts

Interesting Facts about 9-[2-(diethylamino)ethyl]-3,4-dihydro-2H-carbazol-1-one

9-[2-(diethylamino)ethyl]-3,4-dihydro-2H-carbazol-1-one, often referred to in the literature as a member of the carbazole family, has captured the attention of chemists for various remarkable reasons:

  • Pharmaceutical Applications: This compound serves as a *pharmacophore* in several medicinal chemistry projects aimed at developing novel therapeutics, exhibiting properties useful in treating conditions like cancer and neurological disorders.
  • Structural Features: The structure of this compound features a unique *carbazole moiety*, which is known for its *planar conjugated system*, making it an interesting target for research in electronic applications, such as organic semiconductors and fluorescence.
  • Role as a Fluorescent Probe: Due to its electronic structure, 9-[2-(diethylamino)ethyl]-3,4-dihydro-2H-carbazol-1-one has potential uses in *fluorescent imaging*, allowing scientists to track biological processes in living cells.
  • Research and Development: Ongoing studies explore derivatives of this compound to enhance *selectivity and potency* in various biological assays, showcasing its significance in the field of *drug discovery*.
  • Synthetic Pathways: The synthesis of this compound involves *multistep reactions* that demonstrate the intricacies of organic chemistry, providing valuable learning opportunities for students and researchers alike.

As noted by many researchers, "The understanding of such compounds drives the innovation in medicinal chemistry and materials science." This compound's versatility makes it a fascinating subject for both theoretical exploration and practical application.

With numerous avenues for research, the study of 9-[2-(diethylamino)ethyl]-3,4-dihydro-2H-carbazol-1-one exemplifies how a single compound can bridge multiple disciplines in science.