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Carbamazepine

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Identification
Molecular formula
C15H21N3O5
CAS number
298-46-4
IUPAC name
9-[2-(dimethylamino)ethyl]-6-methoxy-3,4-dihydro-2H-carbazol-1-one
State
State

Carbamazepine is typically found in a solid state under room temperature conditions. It is usually stored in its crystalline form and does not have volatility under normal circumstances.

Melting point (Celsius)
189.00
Melting point (Kelvin)
462.15
Boiling point (Celsius)
469.75
Boiling point (Kelvin)
742.90
General information
Molecular weight
236.28g/mol
Molar mass
236.2750g/mol
Density
1.2900g/cm3
Appearence

Carbamazepine appears as a white to off-white crystalline powder. It is odorless and tasteless. The compound is stable under normal temperatures and pressures, though it is recommended to store it away from light and moisture.

Comment on solubility

Solubility of 9-[2-(dimethylamino)ethyl]-6-methoxy-3,4-dihydro-2H-carbazol-1-one

The solubility of 9-[2-(dimethylamino)ethyl]-6-methoxy-3,4-dihydro-2H-carbazol-1-one can be described with the following key points:

  • Polar vs Nonpolar Characteristics: This compound contains both polar and nonpolar functional groups, which can significantly influence its solubility in various solvents.
  • Solvent Preferences: Typically, compounds that have polar functional groups like the dimethylamino group may exhibit increased solubility in polar solvents, such as:
    • Water
    • Methanol
    • Ethanol
    • Dimethyl sulfoxide (DMSO)
  • Conversely, due to its hydrophobic components, this compound may show limited solubility in nonpolar solvents like:
    • Hexane
    • Chloroform
    • Benzene
  • Temperature Effects: Generally, solubility increases with temperature. Therefore, carefully adjusting temperature during dissolution can be beneficial.

In conclusion, understanding the solubility profile of 9-[2-(dimethylamino)ethyl]-6-methoxy-3,4-dihydro-2H-carbazol-1-one is essential for various applications, particularly in pharmaceutical formulations where solubility can directly impact drug efficacy. It is always useful to carry out solubility tests in different solvents to determine the most suitable conditions for this compound.

Interesting facts

Interesting Facts about 9-[2-(dimethylamino)ethyl]-6-methoxy-3,4-dihydro-2H-carbazol-1-one

This intriguing compound features a complex structure and presents a rich area for exploration in the field of organic chemistry. The unique framework of carbazole derivatives has drawn attention for their potential applications in various domains:

  • Pharmacological Significance: This compound is linked to numerous biological activities, making it a subject of interest in medicinal chemistry. It's studied for its possible roles in treating disorders associated with the central nervous system.
  • Synthetic Versatility: The synthesis of this compound often involves multi-step reactions, which serves as a great practical example for chemistry students studying reaction mechanisms and functional group transformations.
  • Fluorescent Properties: Like many carbazole derivatives, this compound may exhibit interesting optical properties, which could make it useful in developing fluorescent probes or materials in optoelectronic applications.
  • Structure-Activity Relationship (SAR): The presence of the dimethylamino and methoxy groups can heavily influence its reactivity and interaction with biological targets, providing a valuable case study for SAR analyses.

As noted by chemists, "The beauty of complexity can unlock the doors to innovative therapies." Understanding this compound not only enhances our knowledge of chemical interactions but also inspires future research into novel applications.

Overall, 9-[2-(dimethylamino)ethyl]-6-methoxy-3,4-dihydro-2H-carbazol-1-one stands as a testament to the fascinating interplay between structure and function in organic chemistry.