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Galantamine

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Identification
Molecular formula
C17H21NO3
CAS number
357-70-0
IUPAC name
9-(2,3,4,6,7,8,9,9a-octahydro-1H-quinolizin-1-ylmethyl)-6-methyl-3,4-dihydro-2H-carbazol-1-one
State
State

Galantamine is typically in a solid state at room temperature.

Melting point (Celsius)
126.50
Melting point (Kelvin)
399.65
Boiling point (Celsius)
542.30
Boiling point (Kelvin)
815.45
General information
Molecular weight
287.37g/mol
Molar mass
287.3720g/mol
Density
1.4000g/cm3
Appearence

Galantamine is typically found in the form of crystalline powder. It is a white or almost white substance, which may also appear as off-white depending on purity and conditions.

Comment on solubility

Solubility Profile

The solubility of 9-(2,3,4,6,7,8,9,9a-octahydro-1H-quinolizin-1-ylmethyl)-6-methyl-3,4-dihydro-2H-carbazol-1-one can be quite complex due to its intricate molecular structure. Understanding its solubility characteristics is crucial for applications in pharmaceuticals and material science.

Factors Affecting Solubility

  • Molecular Structure: The extensive ring systems and functional groups in the compound can influence its interaction with solvents.
  • Polarity: The balance between polar and non-polar groups within the molecule plays a significant role in its solubility in various solvents.
  • Temperature: Generally, an increase in temperature can enhance solubility, but this can vary based on the unique properties of the compound.
  • pH of the solution: For compounds with acidic or basic groups, the pH can substantially impact solubility.

General Observations

It is often observed that compounds similar to this one, with a significant presence of hydrophobic regions, may demonstrate limited solubility in water, leading to a preference for organic solvents. As quoted by many researchers, "Like dissolves like," indicating that non-polar solvents may provide a more suitable medium for dissolution.

In conclusion, while specific solubility data for this compound may be sparse, careful consideration of its molecular characteristics can guide predictions of its behavior in various solvent systems.

Interesting facts

Interesting Facts about 9-(2,3,4,6,7,8,9,9a-octahydro-1H-quinolizin-1-ylmethyl)-6-methyl-3,4-dihydro-2H-carbazol-1-one

This compound, with a complex structure, showcases the fascinating world of heterocyclic chemistry. It belongs to a class of molecules that are of significant interest in pharmaceutical research due to their potential biological activities. Here are some points that make this compound particularly noteworthy:

  • Unique Structure: The octahydro-1H-quinolizin moiety offers interesting stereochemical features that may influence the compound's biological properties.
  • Pharmacological Potential: Compounds like this one are often evaluated for their anti-inflammatory, antifungal, and anticancer activities, making them important in the drug discovery process.
  • Chemical Versatility: The presence of multiple functional groups within its structure allows for possible modifications, enabling the design of derivatives that can enhance efficacy or reduce toxicity.
  • Research Interest: As a chemist or student of chemistry, exploring the synthesis and reactivity of such compounds can lead to innovative methodologies in organic synthesis.

Exploring compounds with intricate structures like this one reveals the beauty of chemistry in nature and its crucial role in developing new therapeutic agents. As we delve deeper into such compounds, we unravel not just their potential uses but also the sophisticated synthetic routes required to create them.

"In every molecule, there is a story waiting to be told."