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Mycalamide A

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Identification
Molecular formula
C28H41NO9
CAS number
123334-00-1
IUPAC name
9-[4-[(2S,3R,4R,5S)-3,4-dihydroxy-5-[[(2S,3S)-3-[(1S,2S)-2-hydroxy-1-methyl-propyl]oxiran-2-yl]methyl]tetrahydropyran-2-yl]-3-methyl-but-2-enoyl]oxynonanoic acid
State
State

At room temperature, Mycalamide A is typically found in a solid state. It is stable under ordinary conditions but should be handled carefully due to its biological activity and potential chemical instability upon exposure to extreme conditions like high temperatures or moisture.

Melting point (Celsius)
179.00
Melting point (Kelvin)
452.00
Boiling point (Celsius)
314.00
Boiling point (Kelvin)
587.00
General information
Molecular weight
529.62g/mol
Molar mass
529.6240g/mol
Density
1.3000g/cm3
Appearence

Mycalamide A appears as a crystalline solid. It is colorless or may appear as white crystalline powder depending on its purity and other physical conditions. Its appearance is typical for many natural marine compounds and is used frequently in research settings.

Comment on solubility

Solubility of 9-[4-[(2S,3R,4R,5S)-3,4-dihydroxy-5-[[(2S,3S)-3-[(1S,2S)-2-hydroxy-1-methyl-propyl]oxiran-2-yl]methyl]tetrahydropyran-2-yl]-3-methyl-but-2-enoyl]oxynonanoic acid

The solubility of the complex compound C28H41NO9 can be described as follows:

  • General Behavior: Due to its large size and intricate structure, this compound exhibits limited solubility in water.
  • Solvent Compatibility: It may dissolve better in organic solvents like ethanol, methanol, or dimethyl sulfoxide (DMSO) rather than in polar solvents.
  • pH Dependence: The presence of multiple hydroxyl groups and the carboxylic acid functional group can alter solubility with changes in pH.
  • Hydrophobic Interactions: The long hydrocarbon chain suggests that hydrophobic interactions might influence solubility favorably in non-polar solvents.

In summary, the solubility of this compound is significantly affected by solvent choice, pH, and temperature, making it unique within the realm of chemical compounds. Always consider conducting specific solubility tests for precise applications.

Interesting facts

Interesting Facts about 9-[4-[(2S,3R,4R,5S)-3,4-dihydroxy-5-[[(2S,3S)-3-[(1S,2S)-2-hydroxy-1-methyl-propyl]oxiran-2-yl]methyl]tetrahydropyran-2-yl]-3-methyl-but-2-enoyl]oxynonanoic acid

This remarkable compound is recognized for its intricate molecular structure and diverse biological activities. Here are some noteworthy aspects:

  • Biological Relevance: This compound resembles natural product scaffolds that have been identified in various biological systems, highlighting its significance in pharmaceutical research.
  • Synthesis Challenges: The synthesis of this compound is a testament to modern organic chemistry, as its multi-step synthesis involves carefully controlled conditions to ensure the fidelity of each stereocenter.
  • Potential Applications: Given its complex structure, this compound may serve as a lead molecule in drug discovery, particularly targeting diseases associated with metabolic disorders or infections.
  • Chirality: Its multiple chiral centers contribute to its specificity in biological interactions, making chirality an essential consideration during synthesis and formulation.

As a student of chemistry, one might find it fascinating to explore how the modification of specific functional groups can lead to significant changes in biological activity and stability. The presence of hydroxyl (-OH) groups, for instance, often enhances solubility and bioactivity. As the famous chemist Linus Pauling once said, "The best way to have a good idea is to have lots of ideas," and this compound surely inspires a wealth of creative research possibilities.

In conclusion, 9-[4-[(2S,3R,4R,5S)-3,4-dihydroxy-5-[[(2S,3S)-3-[(1S,2S)-2-hydroxy-1-methyl-propyl]oxiran-2-yl]methyl]tetrahydropyran-2-yl]-3-methyl-but-2-enoyl]oxynonanoic acid not only exemplifies the complexity of organic compounds but also highlights the ongoing relationship between chemical research and medicinal applications.

Synonyms
SCHEMBL1027618
9-[4-[(2S,3R,4R,5S)-3,4-dihydroxy-5-[[(2S,3S)-3-[(2S,3S)-3-hydroxybutan-2-yl]-2-oxiranyl]methyl]-2-oxanyl]-3-methyl-1-oxobut-2-enoxy]nonanoic acid
Q27166367