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Guanosine

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Identification
Molecular formula
C10H13N5O5
CAS number
118-00-3
IUPAC name
9-[4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]-3H-purin-6-one
State
State

At room temperature, guanosine is in a solid state, typically as a crystalline powder. It is stable under normal conditions.

Melting point (Celsius)
239.00
Melting point (Kelvin)
512.00
Boiling point (Celsius)
0.00
Boiling point (Kelvin)
0.00
General information
Molecular weight
283.24g/mol
Molar mass
283.2410g/mol
Density
2.4000g/cm3
Appearence

Guanosine is a white to off-white crystalline powder. It is typically found as a solid and characterized by its purine base guanine linked to a ribose sugar.

Comment on solubility

Solubility of 9-[4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]-3H-purin-6-one

The solubility of the compound 9-[4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]-3H-purin-6-one, with the chemical formula C10H13N5O5, presents several intriguing characteristics. Understanding its solubility profile can provide insights into its behavior in various environments:

  • Polarity: Due to the presence of multiple hydroxyl (-OH) groups and a purine structure, this compound is likely to exhibit a degree of polarity. This makes it more soluble in polar solvents such as water.
  • Hydrogen Bonding: The compound's ability to form hydrogen bonds enhances its solubility in aqueous mediums, allowing it to interact effectively with solvent molecules.
  • Concentration Effects: At higher concentrations, the solubility may be influenced by factors such as temperature and pH, potentially leading to changes in the compound's dissolution rate.

In general, one can expect this compound to have a moderate to high solubility in water, attributed to its functional groups. However, it is essential to conduct empirical testing to determine precise solubility values, as interactions with other molecules in solution can significantly affect solubility behavior.

Quote: "The solubility of a compound is a pivotal property that dictates its utility in pharmaceuticals and biochemical applications."
Thus, knowledge of solubility is essential for practical applications.

Interesting facts

Interesting Facts about 9-[4-Hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]-3H-purin-6-one

This compound, commonly referred to as a type of modified purine, offers a fascinating glimpse into the world of biochemistry and medicinal chemistry. Here are some engaging facts that highlight its significance:

  • Biological Importance: Compounds like this one are closely related to nucleic acids, playing essential roles in the structure and function of DNA and RNA. Purines are fundamental building blocks for cellular components.
  • Therapeutic Potential: Research is ongoing into the application of modified purines in treatments for various diseases, including cancer. Their ability to interfere with nucleic acid synthesis makes them valuable in drug design.
  • Structure-Activity Relationship: The presence of functional groups like the hydroxymethyl and hydroxy groups can significantly influence the compound's biological activity. This opens up pathways for synthetic modifications to enhance efficacy.
  • Nature-Inspired Chemistry: The incorporation of a tetrahydrofuran ring reflects the intricate design that nature uses in its biochemistry. Such structures can lead to unique interactions at the molecular level.
  • Research Focus: This compound is the subject of various studies aimed at understanding its metabolic pathways and mechanisms of action, providing insights that can lead to the development of new therapeutic agents.

As scientists delve deeper into the properties and applications of compounds like 9-[4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]-3H-purin-6-one, the implications for health, disease treatment, and biotechnology are immense. Its structural complexity invites a continued examination of its potential in cutting-edge research.