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Ganciclovir

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Identification
Molecular formula
C9H13N5O4
CAS number
82410-32-0
IUPAC name
9-[5-(hydroxymethyl)tetrahydrofuran-2-yl]-3H-purin-6-one
State
State

Ganciclovir is a solid at room temperature and is primarily found in crystalline form. It is stable under normal conditions, though it should be stored in a cool, dry place to maintain its efficacy.

Melting point (Celsius)
250.00
Melting point (Kelvin)
523.15
Boiling point (Celsius)
624.20
Boiling point (Kelvin)
897.35
General information
Molecular weight
255.23g/mol
Molar mass
255.2310g/mol
Density
1.6963g/cm3
Appearence

Ganciclovir typically appears as a white to off-white crystalline powder. It is an antiviral medication used to treat cytomegalovirus (CMV) infections. Due to its molecular structure, it should be handled carefully to avoid contact.

Comment on solubility

Solubility of 9-[5-(hydroxymethyl)tetrahydrofuran-2-yl]-3H-purin-6-one

The solubility of the compound 9-[5-(hydroxymethyl)tetrahydrofuran-2-yl]-3H-purin-6-one (C9H13N5O4) can be influenced by several factors including its molecular structure and the presence of functional groups. Here are some key points regarding its solubility:

  • Polarity: The presence of hydroxymethyl and purine groups increases polarity, potentially enhancing solubility in polar solvents such as water.
  • Hydrogen bonding: The ability of the hydroxymethyl group to form hydrogen bonds can significantly improve interactions with water, suggesting relatively good solubility.
  • Solvent compatibility: This compound is expected to be more soluble in organic solvents than in non-polar solvents due to its functional groups.
  • pH dependence: Solubility can also change with pH; the ionization of the amine groups may increase solubility in more basic solutions.

In conclusion, while specific solubility data may vary, the structural characteristics of C9H13N5O4 imply that it is likely more soluble in polar environments. As a general trend, compounds with similar functional groups exhibit enhanced solubility in aqueous conditions, making them more bioavailable and reactive.

Interesting facts

Interesting Facts about 9-[5-(hydroxymethyl)tetrahydrofuran-2-yl]-3H-purin-6-one

The compound known as 9-[5-(hydroxymethyl)tetrahydrofuran-2-yl]-3H-purin-6-one is a fascinating member of the purine family. This compound not only embodies the structural complexity typical of purines but also showcases interesting biochemical activities that intrigue both scientists and students alike.

Key Highlights:

  • Structure & Function: This compound features a purine base linked to a tetrahydrofuran moiety, placing it in a unique chemical category that can interact with biological systems in specific ways.
  • Biological Significance: Purines, including this compound, are essential in various biological processes. They play a crucial role in cellular signaling, energy transfer (as seen in ATP), and are fundamental components of nucleic acids.
  • Potential Applications: Due to its structural similarities to nucleobases, there is ongoing research into how modifications like hydroxymethyl groups can enhance pharmacological profiles, paving the way for novel therapeutic agents.
  • Research Interest: This compound is of particular interest in medicinal chemistry, where studies focus on its interactions with enzymes and receptors, potentially leading to breakthroughs in treating diseases such as cancer and viral infections.
  • Challenging Synthesis: The synthesis of such complex molecules is a testimony to the creativity and skill required in organic chemistry, involving a series of selective reactions that can be both challenging and rewarding.

Scientists often quote, “Chemistry is not just about formulas; it’s about understanding the world at a molecular level.” With compounds like 9-[5-(hydroxymethyl)tetrahydrofuran-2-yl]-3H-purin-6-one, we delve deeper into fascinating interactions that define life itself. Its exploration can lead to a better understanding of biochemical pathways and inspire the design of innovative drugs.

As we continue to unlock the secrets of substances like this one, the potential for new discoveries remains vast, highlighting the importance of continued research in the field of chemistry.