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9-allyl-3-[o-tolyl(phenyl)methoxy]-9-azabicyclo[3.3.1]nonane

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Identification
Molecular formula
C27H33NO
CAS number
18105-78-3
IUPAC name
9-allyl-3-[o-tolyl(phenyl)methoxy]-9-azabicyclo[3.3.1]nonane
State
State

At room temperature, this compound is typically found as a solid.

Melting point (Celsius)
135.00
Melting point (Kelvin)
408.15
Boiling point (Celsius)
345.00
Boiling point (Kelvin)
618.15
General information
Molecular weight
375.54g/mol
Molar mass
375.5440g/mol
Density
1.1200g/cm3
Appearence

The compound appears as a colorless crystalline solid.

Comment on solubility

Solubility of 9-allyl-3-[o-tolyl(phenyl)methoxy]-9-azabicyclo[3.3.1]nonane

The solubility of organic compounds, such as 9-allyl-3-[o-tolyl(phenyl)methoxy]-9-azabicyclo[3.3.1]nonane, often depends on factors like molecular structure, polarity, and the presence of functional groups. In general, the solubility behavior of this compound can be characterized by the following:

  • Molecular Structure: The bicyclic structure contributes a unique arrangement of hydrophobic and hydrophilic regions.
  • Functional Groups: The presence of alkyl and aromatic groups generally enhances non-polar interactions, which may affect overall solubility in water.
  • Polarity: The balance between polar and non-polar elements in the molecular structure will dictate the compound's ability to dissolve in polar solvents (like water) versus non-polar solvents (like hexane).

Given these considerations, it can be expected that:

  • Moderate Solubility in Organic Solvents: Compounds with such structural features generally exhibit better solubility in organic solvents such as ethanol or dichloromethane.
  • Limited Solubility in Water: Due to its complex structure and the presence of large hydrophobic moieties, water solubility may be significantly low.

To wrap up, the solubility of 9-allyl-3-[o-tolyl(phenyl)methoxy]-9-azabicyclo[3.3.1]nonane reflects an interplay of numerous factors that predominantly favor solubility in non-polar environments.

Interesting facts

Interesting Facts about 9-allyl-3-[o-tolyl(phenyl)methoxy]-9-azabicyclo[3.3.1]nonane

The compound 9-allyl-3-[o-tolyl(phenyl)methoxy]-9-azabicyclo[3.3.1]nonane is a fascinating example of a bicyclic structure that exhibits unique chemical properties due to its complex molecular framework. This compound belongs to a family of N-substituted bicyclic amines, which are often studied for their potential applications in various fields. Here are some key points that highlight its significance:

  • Complex Structure: The bicyclic nature of this compound provides a unique scaffold that can influence both its reactivity and biological activity. The interconnected rings create steric hindrance and electronic effects that are crucial for its interactions.
  • Synthetic Challenges: The synthesis of this compound can be quite intricate, often requiring multi-step processes to build and modify the bicyclic system while ensuring correct stereochemistry. Chemists use various strategies to achieve the desired structure without unwanted side reactions.
  • Potential Biological Activity: Compounds with bicyclic amine structures are often evaluated for their pharmacological activity. It's interesting to note that they can act as ligands in neurotransmitter systems and might have therapeutic applications in treating neurological disorders.
  • Research Applications: With ongoing research into similar compounds, there’s a growing interest in their use in drug design and development, particularly in the fields of medicinal chemistry and neuropharmacology.
  • Structure-Activity Relationship (SAR): Understanding how modifications to the bicyclic framework impact biological activity is an essential area of study. This can lead to the optimization of lead compounds in drug discovery.

As remarked by chemists in the field, "The world of bicyclic compounds is a treasure trove for discoveries waiting to be made." The study of 9-allyl-3-[o-tolyl(phenyl)methoxy]-9-azabicyclo[3.3.1]nonane holds promise for uncovering new insights into its functionality and applications in medicinal sciences.

Synonyms
KSD 2444
6606-00-4
N-Allyl-norgranatanol-3-alpha-(2-methylbenzhydryl)aether [German]
9-Allyl-3-alpha-(o-methyldiphenylmethoxy)-9-azabicyclo(3.3.1)nonane
9-AZABICYCLO(3.3.1)NONANE, 9-ALLYL-3-alpha-(o-METHYLDIPHENYLMETHOXY)-
9-Azabicyclo(3.3.1)nonane, 3-alpha-(o-methyldiphenylmethoxy)-9-(2-propen-1-yl)-
N-Allyl-norgranatanol-3-alpha-(2-methylbenzhydryl)aether
DTXSID20984530
3-[(2-METHYLPHENYL)(PHENYL)METHOXY]-9-(PROP-2-EN-1-YL)-9-AZABICYCLO[3.3.1]NONANE