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9-Aminoacridin-2-ol

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Identification
Molecular formula
C13H10N2O
CAS number
1516-81-4
IUPAC name
9-aminoacridin-2-ol
State
State

At room temperature, 9-Aminoacridin-2-ol is usually in a solid state. Its crystalline form is stable under normal conditions, and it needs to be handled with care due to potential chemical reactivity.

Melting point (Celsius)
225.00
Melting point (Kelvin)
498.15
Boiling point (Celsius)
403.00
Boiling point (Kelvin)
676.15
General information
Molecular weight
226.26g/mol
Molar mass
226.2570g/mol
Density
1.3030g/cm3
Appearence

9-Aminoacridin-2-ol typically appears as a yellow crystalline powder. Due to its structure, it can exhibit fluorescence when exposed to UV light, which is a common characteristic of acridine derivatives. Its yellow hue is due to the conjugated aromatic ring system which can absorb certain wavelengths of light.

Comment on solubility

Solubility of 9-aminoacridin-2-ol

9-aminoacridin-2-ol, with its complex structure, exhibits some interesting solubility characteristics. This compound's solubility can be influenced by several factors, making it a fascinating study in the field of chemistry. Here are some key points:

  • Polar and Non-polar Solvents: 9-aminoacridin-2-ol exhibits solubility in both polar and certain non-polar solvents, although it is more soluble in polar solvents such as water and ethanol.
  • pH Influence: The solubility of this compound can be significantly affected by the pH of the solution. It tends to be more soluble in acidic conditions where the amino group can become protonated.
  • Temperature Effects: Like many compounds, increased temperature generally leads to enhanced solubility in liquids, allowing for better dissolution of 9-aminoacridin-2-ol.
  • Complex Formation: This compound can form complexes with various ions or other molecules, potentially affecting its overall solubility profile.

In exploring the solubility of 9-aminoacridin-2-ol, one may conclude that this compound showcases versatile behavior in solution, reflecting its unique structural properties and the chemical environment it encounters. Understanding these solubility dynamics is crucial for its applications in biochemical and pharmaceutical contexts.

Interesting facts

Interesting Facts about 9-Aminoacridin-2-ol

9-Aminoacridin-2-ol, a fascinating compound belonging to the acridine family, possesses a variety of intriguing attributes and applications. Here are some noteworthy points:

  • Fluorescent Properties: This compound exhibits noteworthy fluorescent characteristics, making it an excellent candidate for use in biological imaging techniques.
  • Antimicrobial Activity: Research has shown that 9-aminoacridin-2-ol has potential antimicrobial properties, which could be crucial in the development of new antibiotics.
  • DNA Binding: The ability of this compound to intercalate with DNA highlights its importance in studies related to genetics and molecular biology. It can be used to probe the structure and dynamics of DNA.
  • Role in Phototherapy: Due to its photophysical properties, 9-aminoacridin-2-ol is being studied for potential applications in photodynamic therapy for cancer treatment.
  • Chemical Versatility: As a member of the acridine derivatives, this compound can undergo various chemical modifications, providing a gateway for synthesizing new compounds with diverse functionalities.

This compound not only presents challenges for synthetic chemists but also offers vast opportunities in fields such as pharmacology and bioengineering. As we continue to explore its properties, 9-aminoacridin-2-ol stands out as a promising subject in chemical research.

Synonyms
9-Amino-2-hydroxyacridine
7132-67-4
CCRIS 7631
2-ACRIDINOL, 9-AMINO-
5-Amino-3-hydroxyacridine (European)
BRN 0173183
DTXSID70221508
4-21-00-06203 (Beilstein Handbook Reference)
2-hydroxy-9-AA
DTXCID30143999
9-aminoacridin-2-ol
acridine, 9-amino-2-hydroxy-
SCHEMBL3366302