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Aminacrine

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Identification
Molecular formula
C13H10N2O
CAS number
90-45-9
IUPAC name
9-aminoacridin-4-ol
State
State

Aminacrine is typically a solid at room temperature.

Melting point (Celsius)
243.00
Melting point (Kelvin)
516.20
Boiling point (Celsius)
527.30
Boiling point (Kelvin)
800.40
General information
Molecular weight
210.24g/mol
Molar mass
210.2420g/mol
Density
1.3389g/cm3
Appearence

Aminacrine appears as yellow to brownish-yellow crystalline powder. It is known for its intense color and is often used as a dye or in fluorescent microscopy due to its bright luminescence under ultraviolet light.

Comment on solubility

Solubility of 9-aminoacridin-4-ol

9-aminoacridin-4-ol, a compound known for its various applications, exhibits moderate solubility in water. Solubility can significantly impact its usability and effectiveness in different environments. Here are some key points regarding the solubility of this compound:

  • Water Solubility: 9-aminoacridin-4-ol dissolves in water to a certain extent, allowing for its use in aqueous solutions.
  • Solvent Compatibility: This compound is also soluble in organic solvents, making it versatile for various chemical reactions.
  • pH Dependency: The solubility may alter with changes in pH, showcasing greater dissolution in acidic environments due to protonation of the amino group.
  • Effect of Temperature: Increasing temperature can enhance solubility, a common behavior for many organic compounds.

As with many chemical substances, it is essential to consider the context of solubility, as it directly affects reactivity, stability, and interactions with other compounds. Understanding the solubility characteristics can provide valuable insights for practical applications in laboratory settings and industry.

Interesting facts

Interesting Facts about 9-aminoacridin-4-ol

9-aminoacridin-4-ol is a fascinating compound that has garnered attention in both chemical and biological research due to its unique properties and diverse applications. Here are some noteworthy facts:

  • Structure and Function: This compound belongs to the acridine family, which is known for its aromatic and planar structure. The presence of an amino group enhances its ability to interact with various biological targets.
  • Antimicrobial Properties: Research indicates that 9-aminoacridin-4-ol exhibits antibacterial and antifungal activities, making it a candidate for developing antimicrobial agents. Certain studies have shown it to be effective against specific pathogens, showcasing its potential as a therapeutic compound.
  • DNA Binding: A prominent characteristic of 9-aminoacridin-4-ol is its ability to bind to DNA. This interaction can lead to intercalation, which may influence DNA replication and transcription processes. Such mechanisms are valuable for understanding drug design and genetic regulation.
  • Fluorescent Properties: This compound can display fluorescence due to its aromatic structure. This property has made it useful in biological imaging and tracking studies in cellular environments.
  • Historical Significance: Compounds like 9-aminoacridin-4-ol have been explored as potential antimalarial agents. Their development marks a point in history where chemistry, pharmacology, and medicine intersect.

In summary, 9-aminoacridin-4-ol is not just an ordinary compound; it serves as a crucial link among various scientific fields. Its unique properties make it a remarkable subject of study, highlighting the continuous avenues of research and innovation within the realm of chemistry.

Synonyms
4-ACRIDINOL, 9-AMINO-
23045-33-2
BRN 0173338
5-Amino-1-hydroxyacridine (European)
DTXSID50177610
5-22-12-00249 (Beilstein Handbook Reference)
RefChem:289678
DTXCID10100101
9-aminoacridin-4-ol
Prestwick0_000448
Prestwick1_000448
Prestwick2_000448
SPBio_002435
acridine, 9-amino-4-hydroxy-
CHEMBL1741616
NCGC00016975-01