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9-Fluoro-1,2,3,4,5,6-hexahydroazepino[4,5-b]indole

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Identification
Molecular formula
C14H15FN2
CAS number
Not available
IUPAC name
9-fluoro-1,2,3,4,5,6-hexahydroazepino[4,5-b]indole
State
State

At room temperature, 9-Fluoro-1,2,3,4,5,6-hexahydroazepino[4,5-b]indole is generally a solid. This is typical of organic compounds with several rings and the presence of functional groups like indole and azepine derivatives.

Melting point (Celsius)
126.00
Melting point (Kelvin)
399.15
Boiling point (Celsius)
366.00
Boiling point (Kelvin)
639.15
General information
Molecular weight
221.27g/mol
Molar mass
221.2690g/mol
Density
1.3000g/cm3
Appearence

9-Fluoro-1,2,3,4,5,6-hexahydroazepino[4,5-b]indole typically appears as a white to off-white crystalline solid, indicative of many organic compounds containing a fluorine atom.

Comment on solubility

Solubility of 9-fluoro-1,2,3,4,5,6-hexahydroazepino[4,5-b]indole

The solubility of 9-fluoro-1,2,3,4,5,6-hexahydroazepino[4,5-b]indole in various solvents plays a crucial role in its applications and behavior in chemical processes. Understanding its solubility can enhance its utility in fields such as pharmaceuticals and organic synthesis.

  • Solvent Interaction: The solubility of this compound typically varies based on the polarity of the solvent. It tends to show better solubility in:
    • Polar solvents like water and methanol, due to the presence of polar functional groups.
    • Non-polar solvents can significantly reduce its solubility.
  • Temperature Effects: The solubility can also be influenced by temperature. Generally, increasing the temperature:
    • Tends to improve solubility for most organic compounds due to enhanced molecular motion.
    • Should be experimentally determined, as some compounds may exhibit exceptions.
  • pH Sensitivity: There may be pH-dependent solubility characteristics owing to the specific functional groups present, leading to:
    • Enhanced solubility in acidic or basic environments.
    • Specific forms of the compound being more soluble at different pH levels.

To summarize, *9-fluoro-1,2,3,4,5,6-hexahydroazepino[4,5-b]indole* demonstrates solubility characteristics influenced by solvent polarity, temperature, and pH. These factors must be significantly considered when utilizing this compound in practical applications.

Interesting facts

Interesting Facts about 9-Fluoro-1,2,3,4,5,6-hexahydroazepino[4,5-b]indole

The compound 9-Fluoro-1,2,3,4,5,6-hexahydroazepino[4,5-b]indole is a fascinating member of the indole family that captures the attention of many scientists and researchers. Its unique structure and potential biological activities make it a topic of interest in various fields, particularly medicinal chemistry.

Chemical Structure and Properties

This compound features a complex fused ring system, which arises from the indole structure and the added hexahydroazepine. These rings contribute to its intriguing characteristics:

  • Fluorine Substitution: The presence of the fluorine atom significantly alters the compound's reactivity and biological interactions, as fluorine is known for its electronegativity.
  • Rigidity: The fused ring system enhances the rigidity of the molecule, which can be beneficial for binding to biological targets.

Biological Significance

Compounds similar to 9-fluoro-1,2,3,4,5,6-hexahydroazepino[4,5-b]indole have shown promise in various therapeutic applications:

  • Antidepressants: Due to structural similarities with known antidepressant agents, this compound might have potential pharmacological effects.
  • Antitumor Activity: Investigating compounds with indole moieties can often lead to the discovery of new anticancer drugs.
  • Neuroprotective Properties: Research is ongoing to explore how such compounds may protect central nervous system neurons.

Research and Development

Interest in this compound is bolstered by the ongoing research into:

  • Synthesis Methods: Various approaches for synthesizing this compound are being explored to enable easier access for researchers.
  • Activity Evaluation: Studies are focused on evaluating its activity against several biological targets to elucidate its full potential.

In conclusion, 9-Fluoro-1,2,3,4,5,6-hexahydroazepino[4,5-b]indole is not just a chemical curiosity but a compound with significant implications in drug development and therapeutic applications. As research progresses, it may reveal even more about its capabilities and how it can contribute to medicine and pharmaceuticals.

Synonyms
15918-85-1
9-fluoro-1,2,3,4,5,6-hexahydroazepino[4,5-b]indole
AZEPINO(4,5-b)INDOLE, 9-FLUORO-1,2,3,4,5,6-HEXAHYDRO-
BRN 0912813
9-Fluoro-1,2,3,4,5,6-hexahydro-azepino(4,5-b)indole
Azepino(4,5-b)indole, 1,2,3,4,5,6-hexahydro-9-fluoro-
5-23-07-00378 (Beilstein Handbook Reference)
DTXSID90166604