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Ripretinib

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Identification
Molecular formula
C24H27N7O2
CAS number
1442472-39-0
IUPAC name
9-isopropyl-N2,N6-bis[(4-methoxyphenyl)methyl]purine-2,6-diamine
State
State

Ripretinib is typically in a solid state at room temperature, usually existing in the form of a crystalline powder.

Melting point (Celsius)
246.50
Melting point (Kelvin)
519.65
Boiling point (Celsius)
545.00
Boiling point (Kelvin)
818.15
General information
Molecular weight
482.53g/mol
Molar mass
482.6060g/mol
Density
1.3500g/cm3
Appearence

Ripretinib is generally characterized as a crystalline solid which may appear off-white to pale yellow in color.

Comment on solubility

Solubility of 9-isopropyl-N2,N6-bis[(4-methoxyphenyl)methyl]purine-2,6-diamine

The solubility of 9-isopropyl-N2,N6-bis[(4-methoxyphenyl)methyl]purine-2,6-diamine (C24H27N7O2) is a crucial factor for its potential applications in various fields, especially in pharmaceuticals. Understanding its solubility provides insights into its behavior in biological systems and chemical reactions.

Key Points to Consider:

  • Polarity: The presence of multiple functional groups, particularly the methoxy groups, influences the polarity of the molecule, potentially enhancing solubility in polar solvents.
  • Solvent Compatibility: The solubility is likely to be higher in organic solvents such as methanol or dimethyl sulfoxide compared to water, due to the hydrophobic nature of the isopropyl and phenyl groups.
  • pH Dependency: Like many purines, the solubility may vary with pH, affected by the ionization of the amine groups.

In summary, exploring the solubility of this compound is essential for its practical use, and it can be described as:

  1. A compound with potential lower solubility in non-polar solvents.
  2. Possibly more soluble in polar solvents due to the presence of polar functional groups.
  3. Its solubility may be affected by environmental factors such as temperature and pH.

Overall, understanding these solubility characteristics is key to predicting the behavior and interaction of C24H27N7O2 in various systems.

Interesting facts

Interesting Facts about 9-isopropyl-N2,N6-bis[(4-methoxyphenyl)methyl]purine-2,6-diamine

This compound, with its intricate structure and fascinating attributes, holds a unique position in the realm of chemical research, particularly in pharmacology and biochemistry. Below are some intriguing aspects of this purine derivative:

  • Versatile Applications: Due to its chemical structure, this compound is often explored for its potential use in medicinal chemistry. Purines are fundamental to biological processes, making derivatives like this one significant for therapeutic developments.
  • Structure-Activity Relationship (SAR): The presence of different functional groups, such as the isopropyl group and methoxyphenyl moieties, highlights the importance of structure in determining biological activity. Scientists frequently study how modifications to the purine core can enhance drug efficacy.
  • Mechanism of Action: Compounds like this can interact with various biological pathways, including those related to nucleic acids. Understanding how this specific compound behaves in cellular environments offers insights into potential pathways for drug action.
  • Research Potential: The unique substituents in this compound present avenues for further research. Investigating its role as an enzyme inhibitor or a signaling molecule may yield significant findings in the context of disease mechanisms.
  • Chemical Diversity: This compound exemplifies the richness of organic synthesis, showcasing how slight changes in molecular architecture can lead to diverse pharmacological profiles. The exploration of such compounds enhances our understanding of chemical functionality.

As scientists continue to delve into the properties and applications of this compound, it remains an exciting area of study, prompting questions about its potential as a therapeutic agent and its role in advancing chemical research.

Synonyms
myoseverin
267402-71-1
9-Isopropyl-N2,N6-bis(4-methoxybenzyl)-9H-purine-2,6-diamine
2-N,6-N-bis[(4-methoxyphenyl)methyl]-9-propan-2-ylpurine-2,6-diamine
9H-Purine-2,6-diamine, N,N'-bis((4-methoxyphenyl)methyl)-9-(1-methylethyl)-
MFCD02683596
9-Isopropyl-N2,N6-bis-(4-methoxybenzyl)-9H-purine-2,6-diamine
9-Isopropyl-2,6-bis(4-methoxybenzylamino)purine
CHEMBL141689
SCHEMBL13325947
HMS2043N15
BDBM50473494
HSCI1_000041
AKOS027326433
CS-W009672
HY-W008956
SMP2_000092
NCGC00165829-01
AS-56244
DA-75827
M2373
A12366
9-Isopropyl-N*2*,N*6*-bis-(4-methoxy-benzyl)-9H-purine-2,6-diamine
9-ISOPROPYL-N2,N6-BIS[(4-METHOXYPHENYL)METHYL]PURINE-2,6-DIAMINE