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Codeine methyl ether acetate

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Identification
Molecular formula
C21H25NO4
CAS number
125-28-0
IUPAC name
(9-methoxy-3-methyl-2,4,4a,5,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinolin-7-yl) acetate
State
State
This compound is a solid at room temperature.

It typically presents in a crystalline form and is stable under normal conditions.

Melting point (Celsius)
98.00
Melting point (Kelvin)
371.15
Boiling point (Celsius)
387.40
Boiling point (Kelvin)
660.50
General information
Molecular weight
371.44g/mol
Molar mass
371.4440g/mol
Density
1.2000g/cm3
Appearence

The compound is typically a white or off-white crystalline solid. It may appear as a fine powder, and is often odorless or may have a faint odor.

Comment on solubility

Solubility of (9-methoxy-3-methyl-2,4,4a,5,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinolin-7-yl) acetate

The solubility of (9-methoxy-3-methyl-2,4,4a,5,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinolin-7-yl) acetate can be quite nuanced due to its complex structure. Understanding the solubility of this compound involves several key points:

  • Solvent Interaction: The solubility is highly dependent on the polarity of the solvent. Polar solvents, such as water, may struggle to dissolve this compound, while non-polar solvents, such as organic solvents (e.g., ethanol or chloroform), may be more effective.
  • Hydrophobic Nature: The presence of hydrophobic regions in the molecular structure suggests that the compound may have limited solubility in aqueous solutions. This is typical for many large, complex organic compounds.
  • Temperature Effects: Temperature can also influence solubility; higher temperatures often increase solubility in organic solvents, so evaluating the solubility at various temperatures can yield different results.

In summary, while the precise solubility characteristics of this compound require empirical evaluation, it's reasonable to conclude that it may exhibit higher solubility in non-polar or moderately polar solvents compared to highly polar aqueous environments. As with many organic structures, careful experimentation and analysis is necessary to determine the conditions favoring its solubility.

Interesting facts

Interesting Facts about (9-Methoxy-3-methyl-2,4,4a,5,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinolin-7-yl) Acetate

This compound belongs to a class of chemicals that are of significant interest to both medicinal and organic chemists. Its complex structure and unique functional groups present numerous avenues for research and application.

Key Characteristics

  • Structural Diversity: The intricate molecular structure includes multiple rings and functional groups, making it a fascinating subject of study in organic synthesis.
  • Potential Biological Activity: Compounds similar to this one have been investigated for their pharmacological properties, including anti-cancer and anti-inflammatory effects.
  • Importance in Drug Design: The structure can serve as a scaffold for the development of novel therapeutic agents due to its ability to engage in significant molecular interactions.

Noteworthy Applications

  • The compound may hold promise in the field of pharmacology, particularly in the search for alternatives to traditional medications.
  • It's often explored in studies focusing on neuroscience, where compounds influencing the nervous system are of great interest.
  • Researchers are investigating its potential in natural product synthesis, highlighting its versatility and the role it may play in developing other compounds.

As a fascinating chemical, (9-methoxy-3-methyl-2,4,4a,5,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinolin-7-yl) acetate exemplifies the intricate relationship between chemical structure and biological function. Exploring this compound offers valuable insights into both fundamental chemistry and its applications in various scientific domains.

Synonyms
Thebaine, acetate
3-methoxy-17-methyl-6,7-didehydro-4,5-epoxymorphinan-6-yl acetate
Thebaine, acetate (ester)
Demethyldihydrothebanine acetate
SCHEMBL1649199
CHEMBL4743744
DTXSID00861956
NSC117860
NSC404373
NSC-404373
NS00005004
Morphinan-6-ol,7-didehydro-4,5.alpha.-epoxy-3-methoxy-17-methyl-, acetate
WLN: T B6566 B6/CO 4ABBC R BX HO PN EU GHT&&TTJ FOV1 JO1 P1
Morphinan-6-ol,7-didehydro-4,5-epoxy-3-methoxy-17-methyl-, acetate (ester), (5.alpha.)-
Morphinan-6-ol,7-didehydro-4,5.alpha.-epoxy-3-methoxy-17-methyl-, acetate (ester)