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Ibogaine

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Identification
Molecular formula
C20H26N2O
CAS number
83-74-9
IUPAC name
9-methoxy-3,6-dimethyl-1,2,4,5-tetrahydroazepino[4,5-b]indole
State
State

At room temperature, ibogaine is typically in a solid state. Its crystalline form makes it easy to identify through visual and physical inspection.

Melting point (Celsius)
153.00
Melting point (Kelvin)
426.00
Boiling point (Celsius)
330.00
Boiling point (Kelvin)
603.00
General information
Molecular weight
310.45g/mol
Molar mass
310.4020g/mol
Density
1.4500g/cm3
Appearence

Ibogaine typically appears as a crystalline solid. It can range in color from white to a light cream. The appearance of the compound may vary slightly depending on its purity and the form in which it is prepared.

Comment on solubility

Solubility of 9-methoxy-3,6-dimethyl-1,2,4,5-tetrahydroazepino[4,5-b]indole

The solubility of 9-methoxy-3,6-dimethyl-1,2,4,5-tetrahydroazepino[4,5-b]indole can be complex due to its unique molecular structure. Understanding its solubility in various solvents is crucial for applications in pharmaceuticals and chemical synthesis.

Key points regarding the solubility of this compound include:

  • Polarity: The presence of the methoxy group enhances solubility in polar solvents such as ethanol and methanol.
  • Solvent Compatibility: It is generally less soluble in non-polar solvents due to its relatively large aromatic system.
  • Temperature Effects: Increased temperature usually enhances solubility for most organic compounds, including this tetrahydroazepino derivative.
  • pH Dependence: The solubility can vary with changes in pH, particularly if the compound has ionizable protons.

As a result, solubility testing in multiple environments is recommended:

  1. Conduct tests in water for base-line solubility.
  2. Evaluate polar organic solvents to assess solubility range.
  3. Experiment with non-polar solvents for comparative analysis.

In summary, understanding the solubility of 9-methoxy-3,6-dimethyl-1,2,4,5-tetrahydroazepino[4,5-b]indole is fundamental for its effective application in various fields, offering insights into its behavior in biological and chemical settings.

Interesting facts

Interesting Facts about 9-methoxy-3,6-dimethyl-1,2,4,5-tetrahydroazepino[4,5-b]indole

The compound 9-methoxy-3,6-dimethyl-1,2,4,5-tetrahydroazepino[4,5-b]indole is a fascinating molecule that belongs to a larger class of compounds known as indole derivatives. These compounds are renowned for their diverse biological activities, making them significant in multiple fields, including pharmacology and organic synthesis.

Noteworthy Characteristics

  • Structural Complexity: The intricate structure of this compound features a fused ring system, specifically an azepine and indole framework. This complexity often correlates with interesting chemical properties and biological activities.
  • Biological Significance: Many indole derivatives are known to exhibit a range of pharmacological effects, including anti-inflammatory, anti-cancer, and neuroprotective activities. The biological relevance of this compound makes it a subject of ongoing research.
  • Potential Applications: Researchers are exploring the potential of 9-methoxy-3,6-dimethyl-1,2,4,5-tetrahydroazepino[4,5-b]indole in drug development, particularly in treating psychiatric disorders due to its structural resemblance to neurotransmitters.
  • Synthesis Challenges: The synthesis of this compound may involve multi-step organic reactions, showcasing the importance of advanced synthetic techniques in modern chemistry. Chemists often seek new methodologies to efficiently create complex molecules like this one.

As a student or researcher delving into the world of organic chemistry, understanding such compounds can open doors to innovative research and applications. The quote by Linus Pauling resonantly underscores the essence of chemical research: "The best way to have a good idea is to have a lot of ideas." Exploring diverse compounds like 9-methoxy-3,6-dimethyl-1,2,4,5-tetrahydroazepino[4,5-b]indole can lead to groundbreaking discoveries in the future.