Skip to main content

Sildenafil

ADVERTISEMENT
Identification
Molecular formula
C22H30N6O4S
CAS number
171599-83-0
IUPAC name
9-methoxy-6-methyl-1,2,3,4,5,6-hexahydroazepino[4,5-b]indol-6-ium;chloride
State
State

At room temperature, sildenafil is typically found in its solid form.

Melting point (Celsius)
187.00
Melting point (Kelvin)
460.15
Boiling point (Celsius)
583.30
Boiling point (Kelvin)
856.45
General information
Molecular weight
474.58g/mol
Molar mass
474.5760g/mol
Density
1.2709g/cm3
Appearence

Sildenafil generally appears as a white to off-white crystalline powder.

Comment on solubility

Solubility of 9-methoxy-6-methyl-1,2,3,4,5,6-hexahydroazepino[4,5-b]indol-6-ium;chloride

The solubility of a compound can be a crucial factor in determining its utility in various applications, especially in pharmaceuticals and organic chemistry. In the case of 9-methoxy-6-methyl-1,2,3,4,5,6-hexahydroazepino[4,5-b]indol-6-ium;chloride, it exhibits specific solubility characteristics that deserve attention:

  • Solvent Dependence: This compound's solubility is likely influenced by the polarity of the solvent used. Water, as a polar solvent, may dissolve ionic components of the molecule, while non-polar solvents may not be as effective.
  • Ionization: The chloride ion in this compound suggests that it is soluble in aqueous solutions because ionic compounds generally dissociate in water, leading to increased solubility.
  • Structural Factors: The presence of the methoxy group may enhance the solubility in organic solvents, making it more adaptable in non-aqueous environments.
  • Temperature Effects: Like many compounds, solubility may increase with temperature. Heating the solvent could facilitate better dissolution, though care must be taken to avoid decomposition.

Overall, the solubility landscape for 9-methoxy-6-methyl-1,2,3,4,5,6-hexahydroazepino[4,5-b]indol-6-ium;chloride can be summarized with the statement: “solute-solvent interactions are key to understanding the solubility behavior of this complex compound.”

Interesting facts

Interesting Facts about 9-methoxy-6-methyl-1,2,3,4,5,6-hexahydroazepino[4,5-b]indol-6-ium;chloride

The compound 9-methoxy-6-methyl-1,2,3,4,5,6-hexahydroazepino[4,5-b]indol-6-ium;chloride represents a fascinating intersection of organic chemistry and medicinal research. Here are some engaging insights:

  • Unique Structure: This compound features a complex polycyclic structure that incorporates both indole and azepine frameworks, making it intriguing for studies related to medicinal chemistry.
  • Potential Biological Activity: Compounds like this one are often investigated for their potential pharmacological properties. They may exhibit varied biological effects, including antimicrobial, anticonvulsant, or psychoactive properties.
  • Method of Synthesis: The synthesis of such compounds typically involves multistep organic reactions, which may include cyclization and functional group transformations. This skill set is crucial for chemists engaged in drug design.
  • Ionization: The presence of the chloride ion suggests that this compound is a salt, which can influence its solubility and reactivity. Understanding ionization is essential for scientists when considering the behavior of compounds in biological systems.
  • Chemical Versatility: The presence of a methoxy group contributes to the compound's molecular versatility, which can affect its interaction with various biological targets.
  • Historical Significance: Compounds with similar structures have been the basis for numerous pharmaceutical developments over the decades, highlighting the enduring relevance of chemical exploration.
  • Research Applications: Ongoing research in the field may unveil new therapeutic uses, making this compound a potential candidate for future studies.

In summary, 9-methoxy-6-methyl-1,2,3,4,5,6-hexahydroazepino[4,5-b]indol-6-ium;chloride exemplifies the complexity and potential of modern organic compounds in drug discovery, illustrating the importance of thorough chemical understanding and exploration.

Synonyms
15918-70-4
1,2,3,4,5,6-Hexahydro-9-methoxy-6-methyl-azepino(4,5-b)indole hydrochloride
Azepino(4,5-b)indole, 1,2,3,4,5,6-hexahydro-9-methoxy-6-methyl-, monohydrochloride