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9,9-Dimethyl-10-[3-(4-pyrrolidin-1-yl-1-piperidyl)propyl]acridine

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Identification
Molecular formula
C26H32N3
CAS number
165189-51-3
IUPAC name
9,9-dimethyl-10-[3-(4-pyrrolidin-1-yl-1-piperidyl)propyl]acridine
State
State

At room temperature, the compound is in a solid state. It maintains stability as a solid under standard conditions and does not dissolve easily in water, but it may dissolve in organic solvents.

Melting point (Celsius)
117.50
Melting point (Kelvin)
390.65
Boiling point (Celsius)
440.00
Boiling point (Kelvin)
713.15
General information
Molecular weight
386.58g/mol
Molar mass
386.5760g/mol
Density
1.1200g/cm3
Appearence

This compound appears as a crystalline solid. It typically forms white or off-white crystals and is known for its reflective surfaces indicative of solid acridine derivatives.

Comment on solubility

Solubility of 9,9-dimethyl-10-[3-(4-pyrrolidin-1-yl-1-piperidyl)propyl]acridine

The solubility of 9,9-dimethyl-10-[3-(4-pyrrolidin-1-yl-1-piperidyl)propyl]acridine in various solvents can vary significantly based on its structural composition. Generally, compounds with considerable **hydrophobic** character, like this one, tend to exhibit low solubility in **polar solvents** such as water. However, they may be more soluble in **non-polar** or **less polar organic solvents**. Here are some important points regarding its solubility:

  • Polar Solvents: Due to its hydrophobic regions, this compound likely has limited solubility in water.
  • Organic Solvents: It may dissolve better in solvents like chloroform, methylene chloride, or dimethyl sulfoxide (DMSO), which can interact effectively with its large aromatic structure.
  • pH Sensitivity: The solubility could also be influenced by the pH of the solution, particularly if any acidic/basic functional groups are present.
  • Temperature Dependence: An increase in temperature might enhance solubility in organic solvents, consistent with many organic compounds.

In conclusion, the solubility of this compound is a critical consideration for its practical applications. As stated, “Understanding solubility is key to maximizing the efficacy of any compound in pharmacological settings.” Therefore, appropriate solvent choices and conditions must be explored when working with 9,9-dimethyl-10-[3-(4-pyrrolidin-1-yl-1-piperidyl)propyl]acridine.

Interesting facts

Interesting Facts about 9,9-Dimethyl-10-[3-(4-pyrrolidin-1-yl-1-piperidyl)propyl]acridine

This compound, known for its complex structure, is a fascinating subject in the field of medicinal chemistry. Its unique molecular arrangement serves as an intriguing template for exploring potential pharmaceutical applications. Here are some noteworthy aspects:

  • Versatile Structure: The compound contains an acridine core, which is a common scaffold in various bioactive molecules. This core is often linked to diverse functional groups that enhance its therapeutic profiles.
  • Pharmacological Interest: Compounds with piperidine and pyrrolidine moieties are frequently studied for their activity as neuroprotective agents, making this compound a potential candidate for research in neuropharmacology.
  • Research Potential: The introduction of dimethyl and branched alkyl chains into the acridine framework can influence the compound's biological interactions, thus opening avenues for drug design and optimization.
  • Diversity in Functionality: The presence of the piperidyl and pyrrolidinyl substituents suggests that this compound may interact with several receptor systems, possibly leading to varied effects in biological assays.

As highlighted by chemists, "The beauty of synthetic chemistry is in the creation of new possibilities through structural variations." This compound exemplifies that philosophy, as modifications to its structure could potentially lead to groundbreaking discoveries in the realm of therapeutics.

Overall, the exploration of 9,9-dimethyl-10-[3-(4-pyrrolidin-1-yl-1-piperidyl)propyl]acridine not only expands our understanding of acridine derivatives but also emphasizes the importance of innovative approaches in drug development.