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Ambroxol

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Identification
Molecular formula
C13H18Br2N2O
CAS number
18683-91-5
IUPAC name
(9R,10S)-10-aminotricyclo[9.4.0.03,8]pentadeca-1(15),3,5,7,11,13-hexaen-9-ol
State
State

At room temperature, Ambroxol is in a solid state, specifically as a crystalline powder. It is usually stable under standard conditions of temperature and pressure.

Melting point (Celsius)
233.00
Melting point (Kelvin)
506.15
Boiling point (Celsius)
390.00
Boiling point (Kelvin)
663.15
General information
Molecular weight
376.37g/mol
Molar mass
376.3740g/mol
Density
1.0050g/cm3
Appearence

Ambroxol is typically an off-white to pale yellow crystalline powder. It may vary slightly in color depending on the purity and specific conditions of preparation.

Comment on solubility

Solubility of (9R,10S)-10-aminotricyclo[9.4.0.03,8]pentadeca-1(15),3,5,7,11,13-hexaen-9-ol

The solubility of (9R,10S)-10-aminotricyclo[9.4.0.03,8]pentadeca-1(15),3,5,7,11,13-hexaen-9-ol can be understood through several important factors:

  • Polar Nature: This compound contains a hydroxyl group (-OH) which generally increases solubility in polar solvents, particularly water.
  • Structural Complexity: The tricyclic structure of the compound contributes to its overall solubility behavior. Compounds with complex ring structures may have varying solubility depending on their conformational flexibility.
  • Non-Polar Interactions: Despite its polar -OH group, the presence of multiple double bonds and cycloalkane rings may result in some hydrophobic character, possibly limiting solubility in non-polar solvents.

In summary, while (9R,10S)-10-aminotricyclo[9.4.0.03,8]pentadeca-1(15),3,5,7,11,13-hexaen-9-ol is likely to exhibit good solubility in polar solvents due to its hydroxyl group, the intricate ring structure and hydrophobic portions can hinder its solubility in non-polar environments. As stated, “Solubility is influenced by both the functional groups present and the overall molecular architecture.” This compound serves as a prime example of how various physical and chemical factors intersect to determine solubility dynamics.

Interesting facts

Interesting Facts about (9R,10S)-10-aminotricyclo[9.4.0.03,8]pentadeca-1(15),3,5,7,11,13-hexaen-9-ol

(9R,10S)-10-aminotricyclo[9.4.0.03,8]pentadeca-1(15),3,5,7,11,13-hexaen-9-ol is a fascinating compound that showcases unique structural features and potential applications in various fields.

Unique Structural Characteristics

One of the intriguing aspects of this compound is its complex tricyclic framework. Here are some key points:

  • Tricyclic Structure: The arrangement of three fused rings contributes to its stability and reactivity.
  • Stereochemistry: The presence of chiral centers at 9R and 10S gives rise to distinct stereoisomers, each potentially exhibiting different biological activities.
  • Functional Groups: The amino group and hydroxyl group are critical for its reactivity, influencing how the compound interacts with other molecules.

Potential Applications

This compound attracts interest in several research areas:

  • Medicinal Chemistry: Due to its unique structure, it may serve as a lead compound for drug development, particularly in targeting specific diseases or conditions.
  • Material Science: The unusual bonding and electronic properties could lead to advancements in materials, such as organic semiconductors.
  • Biological Research: Understanding its mechanisms could unveil new pathways for biochemical processes.

Scientific Significance

In the words of chemist, "Nature has a way of creating intricate molecules that challenge our understanding and inspire innovation." This compound exemplifies that notion, inviting chemists to explore its properties and unlock its potential.

Overall, (9R,10S)-10-aminotricyclo[9.4.0.03,8]pentadeca-1(15),3,5,7,11,13-hexaen-9-ol represents a captivating subject for scientific inquiry, blending a complex molecular architecture with significant implications for future studies.

Synonyms
5H-DIBENZO(a,d)CYCLOHEPTEN-10-OL, 10,11-DIHYDRO-11-AMINO-, (Z)-
cis-10-Amino-10,11-dihydro-5H-dibenzo(a,d)cyclohepten-11-ol
DTXSID50167152
16144-79-9
DTXCID5089643