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Norethisterone enanthate

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Identification
Molecular formula
C27H38O3
CAS number
3836-23-5
IUPAC name
[(9S,10R,13S,14S,17R)-17-ethynyl-13-methyl-3-oxo-1,2,6,7,8,9,10,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-17-yl] heptanoate
State
State

Norethisterone enanthate is typically in a solid state at room temperature. It is often used in pharmaceutical formulations, requiring proper storage conditions to maintain its stability.

Melting point (Celsius)
61.00
Melting point (Kelvin)
334.15
Boiling point (Celsius)
285.00
Boiling point (Kelvin)
558.15
General information
Molecular weight
430.63g/mol
Molar mass
430.6340g/mol
Density
1.0800g/cm3
Appearence

Norethisterone enanthate is usually a white or creamy white crystalline powder. It is practically insoluble in water, slightly soluble in ethanol, and sparingly soluble in octanol.

Comment on solubility

Solubility of [(9S,10R,13S,14S,17R)-17-ethynyl-13-methyl-3-oxo-1,2,6,7,8,9,10,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-17-yl] heptanoate

The solubility characteristics of the compound [(9S,10R,13S,14S,17R)-17-ethynyl-13-methyl-3-oxo-1,2,6,7,8,9,10,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-17-yl] heptanoate can be complex due to its intricate molecular structure. Here are several important factors about its solubility:

  • Polarity: The solubility largely depends on the presence of polar and nonpolar functional groups in the compound. Such a structure often leads to limited solubility in water.
  • Solvent Interaction: Being an organic compound, it may display significant solubility in organic solvents such as ethanol, methanol, and dichloromethane.
  • Temperature Effects: Like many organic compounds, the solubility may increase with temperature, suggesting that higher temperatures could enhance dissolution in appropriate solvents.

In summary, while [(9S,10R,13S,14S,17R)-17-ethynyl-13-methyl-3-oxo-1,2,6,7,8,9,10,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-17-yl] heptanoate is likely to exhibit poor solubility in polar solvents such as water, it is expected to be more soluble in nonpolar or moderately polar organic solvents. This characteristic can significantly influence its applications and behaviors in various chemical contexts.

Interesting facts

Interesting Facts about 17-Ethynyl-13-methyl-3-oxo-Dodecahydrocyclopenta[a]phenanthrene-17-yl Heptanoate

This compound, with its intricate structure and intriguing functional groups, is a fascinating subject of study within the realm of organic chemistry. Here are some key points that highlight its significance:

  • Steroidal Structure: The compound is classified as a steroid due to its characteristic multi-ring structure, which plays a crucial role in biological processes.
  • Ethynyl Group: The presence of the ethynyl (-C≡CH) moiety enhances the compound's reactivity and can contribute to its unique pharmacological properties.
  • Pharmacological Potential: Compounds of this type may have applications in hormone replacement therapy and might exhibit similar mechanisms to well-known steroids.
  • Biological Relevance: Understanding its interactions with hormone receptors can provide insights into its potential uses in medicine, particularly in treatments related to reproductive health.
  • Mechanistic Studies: Chemists often investigate compounds like this through complex synthesis and mechanistic studies, which can reveal new pathways for interaction and transformation.
  • Stereochemistry: The specified stereochemical configuration indicates that this compound may exhibit specific biological activity due to its chiral centers, thus emphasizing the importance of stereochemistry in pharmacology.

In conclusion, the study of (9S,10R,13S,14S,17R)-17-ethynyl-13-methyl-3-oxo-dodecahydrocyclopenta[a]phenanthren-17-yl heptanoate is not only an exercise in organic synthesis and analytical chemistry but also holds potential for real-world applications in medicine. The complexity of its structure coupled with the vast landscape of its possible interactions presents an exciting avenue for ongoing research.

Synonyms
NCGC00182712-01
SCHEMBL372672