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Corticosterone

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Identification
Molecular formula
C21H30O4
CAS number
50-22-6
IUPAC name
(9S,17S)-17-hydroxy-7,13,17-trimethyl-1,2,6,7,8,9,10,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-3-one
State
State

At room temperature, corticosterone typically exists as a solid.

Melting point (Celsius)
182.00
Melting point (Kelvin)
455.15
Boiling point (Celsius)
537.70
Boiling point (Kelvin)
810.90
General information
Molecular weight
346.47g/mol
Molar mass
346.4690g/mol
Density
1.1700g/cm3
Appearence

Corticosterone is a white or off-white crystalline powder. It has a characteristic odor and is often used in laboratory settings for research purposes.

Comment on solubility

Solubility of (9S,17S)-17-hydroxy-7,13,17-trimethyl-1,2,6,7,8,9,10,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-3-one

The solubility of the compound (9S,17S)-17-hydroxy-7,13,17-trimethyl-1,2,6,7,8,9,10,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-3-one can be quite intricate due to its complex structure and high molecular weight. Generally, the solubility of organic compounds depends on several key factors:

  • Polarity: This compound is likely to exhibit low polarity due to its large hydrophobic (non-polar) regions, affecting its solubility in polar solvents like water.
  • Solvent Compatibility: It may be more soluble in non-polar solvents such as hexane or chloroform rather than in polar solvents, suggesting a preference for organic solvent systems.
  • Hydroxyl Group: The presence of the hydroxyl group (-OH) introduces potential for hydrogen bonding, which can enhance solubility in certain polar solvents to an extent, making it **sparingly soluble**.
  • Molecular Weight: Higher molecular weights can often correlate with lower solubility in water due to decreased molecular motion.

Thus, while predictions can be made about this compound's solubility, specific experimental data would be necessary to fully understand its behavior in various solvent systems. It is essential to **test solubility** under different conditions to ascertain the most suitable solvents for applications.

Interesting facts

Interesting Facts About (9S,17S)-17-hydroxy-7,13,17-trimethyl-1,2,6,7,8,9,10,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-3-one

The compound (9S,17S)-17-hydroxy-7,13,17-trimethyl-1,2,6,7,8,9,10,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-3-one belongs to the class of steroid compounds, which are critical in various biochemical processes. Particularly known for their *hormonal activities*, steroids play significant roles in regulating a myriad of bodily functions.

Key Features

  • Structural Complexity: This compound has a unique bicyclic structure that incorporates intricate cyclic and acyclic components, making it an interesting subject of study in organic chemistry.
  • Biological Significance: Steroid compounds like this one are often precursors to hormones and serve functions in processes such as metabolism and immune responses. They can have profound impacts on **human health**.
  • Potential Applications: Researchers explore its analogs in pharmaceuticals, particularly in the development of drugs targeting hormonal balance and various endocrine-related conditions.
  • Research and Investigation: Its structural attributes could make it a valuable intermediate in synthetic chemistry or as a lead compound for new therapeutic agents.

As a student of chemistry, one can appreciate the *interdisciplinary nature* of this compound's study, as it borders organic chemistry, biochemistry, and medicinal chemistry. One might find it brings together concepts of molecular design and functionality, which are key in the advancement of medical science.

In the words of renowned chemist, "Understanding the structure of molecules opens the door to unraveling their function."
This compound exemplifies that truth in its intricate arrangement and biological importance.