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Acetohydrazide

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Identification
Molecular formula
C2H6N2O
CAS number
1068-57-1
IUPAC name
acetohydrazide
State
State
Acetohydrazide is typically a solid at room temperature.
Melting point (Celsius)
63.00
Melting point (Kelvin)
336.00
Boiling point (Celsius)
209.00
Boiling point (Kelvin)
482.00
General information
Molecular weight
74.08g/mol
Molar mass
74.0820g/mol
Density
1.1700g/cm3
Appearence

Acetohydrazide appears as a white to off-white crystalline solid. It is typically found as a powder with fine particles. The compound is known for its moderate solubility in water, making it easy to handle in various applications.

Comment on solubility

Solubility of Acetohydrazide

Acetohydrazide, with the chemical formula C2H6N2O, exhibits interesting solubility characteristics that are worth noting:

  • Solvent Compatibility: Acetohydrazide is known to be soluble in water, which is a significant property for many applications, especially in organic synthesis.
  • Temperature Influence: Its solubility can increase with temperature, a common trait for many organic compounds.
  • Polar Nature: The presence of both hydrophilic (amino groups) and hydrophobic elements enhances its overall solubility profile. Specifically, the amino (-NH2) group contributes positively to solubility in polar solvents.

As a general rule, compounds with greater polarity tend to be more soluble in water, and acetohydrazide aligns well with this principle. It demonstrates that:

“The more polar a compound, the better it usually dissolves in polar solvents.”

Understanding the solubility of acetohydrazide is crucial for its practical applications in various fields, including pharmaceuticals and agrochemicals, where dissolving capabilities in specific solvents play a key role in efficacy and application.

Interesting facts

Interesting Facts about Acetohydrazide

Acetohydrazide is a fascinating compound that embodies the rich interplay between organic chemistry and pharmacological applications. Here are some intriguing aspects of this unique molecule:

  • Chemical Structure: Acetohydrazide contains a functional hydrazine group, which is known for its reactivity, making it a versatile building block in organic synthesis.
  • Pharmaceutical Potential: This compound has garnered interest in the field of medicinal chemistry due to its potential applications as an anti-tubercular agent. The presence of hydrazine moieties can be pivotal in the synthesis of various pharmaceuticals.
  • Research Significance: Many studies have explored its role in the development of new drugs, showcasing how modifications to the hydrazide structure can lead to enhanced biological activity.
  • Synthesis Methods: Acetohydrazide can be synthesized from the reaction of hydrazine with acetyl compounds, highlighting the significance of understanding reactivity patterns in synthetic organic chemistry.

In summary, acetohydrazide's intriguing chemical properties and potential applications make it a worthwhile compound for further study in both academic and industrial settings. As researchers continue to uncover its capabilities, the impact of this compound within the scientific community is likely to expand.

Synonyms
Acethydrazide
Acetohydrazide
1068-57-1
Acetylhydrazine
Acetic hydrazide
Monoacetylhydrazine
Acetyl hydrazide
N-Acetylhydrazine
Ethanehydrazonic acid
ACETIC ACID, HYDRAZIDE
Hydrazine, acetyl-
Acetyl hydrazine
acetohydrazine
acethydrazine
ENT-61241
Hydrazid kyseliny octove
NSC 53155
NSC 2271
CCRIS 4791
Hydrazid kyseliny octove [Czech]
EINECS 213-948-7
CHEBI:2422
SK0DPC9098
AI3-61241
NSC-2271
NSC-53155
OFLXLNCGODUUOT-UHFFFAOYSA-
acetylhydrazide
213-948-7
inchi=1/c2h6n2o/c1-2(5)4-3/h3h2,1h3,(h,4,5)
Acetic acid hydrazide
Monoacetyl hydrazine
MFCD00007610
WLN: ZMV1
UNII-SK0DPC9098
ethanoic hydrazide
AcN2 deriv
acetohydrazonic acid
acetic acid hydrazone
Acethydrazide, 90%
ethanoic acid hydrazide
methane, hydrazinocarbonyl-
CHEMBL3091859
DTXSID9020900
CHEBI:48978
NSC2271
Ald3-H_000034
CS-D1403
NSC53155
Ald3.1-H_000314
Ald3.1-H_000633
Ald3.1-H_000952
AB6005
BBL018600
STL194154
AKOS000104423
AB00888
GS-3116
BP-30010
Acetyl Hydrazine Contains~10% acetic acid
DB-029410
A0789
Acethydrazide (moist with methylene chloride)
NS00021483
EN300-18497
C07447
Q4678005
Z58981787